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Items: 1 to 20 of 255

1.

eNOS protects from atherosclerosis despite relevant superoxide production by the enzyme in apoE mice.

Ponnuswamy P, Schröttle A, Ostermeier E, Grüner S, Huang PL, Ertl G, Hoffmann U, Nieswandt B, Kuhlencordt PJ.

PLoS One. 2012;7(1):e30193. doi: 10.1371/journal.pone.0030193. Epub 2012 Jan 23.

2.

Antiatherosclerotic effects of small-molecular-weight compounds enhancing endothelial nitric-oxide synthase (eNOS) expression and preventing eNOS uncoupling.

Wohlfart P, Xu H, Endlich A, Habermeier A, Closs EI, Hübschle T, Mang C, Strobel H, Suzuki T, Kleinert H, Förstermann U, Ruetten H, Li H.

J Pharmacol Exp Ther. 2008 May;325(2):370-9. doi: 10.1124/jpet.107.128009. Epub 2008 Feb 5.

3.

A specific role for eNOS-derived reactive oxygen species in atherosclerosis progression.

Takaya T, Hirata K, Yamashita T, Shinohara M, Sasaki N, Inoue N, Yada T, Goto M, Fukatsu A, Hayashi T, Alp NJ, Channon KM, Yokoyama M, Kawashima S.

Arterioscler Thromb Vasc Biol. 2007 Jul;27(7):1632-7. Epub 2007 Apr 26.

4.

Resveratrol reverses endothelial nitric-oxide synthase uncoupling in apolipoprotein E knockout mice.

Xia N, Daiber A, Habermeier A, Closs EI, Thum T, Spanier G, Lu Q, Oelze M, Torzewski M, Lackner KJ, Münzel T, Förstermann U, Li H.

J Pharmacol Exp Ther. 2010 Oct;335(1):149-54. doi: 10.1124/jpet.110.168724. Epub 2010 Jul 7.

5.

Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE-deficient mice.

Ozaki M, Kawashima S, Yamashita T, Hirase T, Namiki M, Inoue N, Hirata K, Yasui H, Sakurai H, Yoshida Y, Masada M, Yokoyama M.

J Clin Invest. 2002 Aug;110(3):331-40.

6.

Decreased production of neuronal NOS-derived hydrogen peroxide contributes to endothelial dysfunction in atherosclerosis.

Capettini LS, Cortes SF, Silva JF, Alvarez-Leite JI, Lemos VS.

Br J Pharmacol. 2011 Nov;164(6):1738-48. doi: 10.1111/j.1476-5381.2011.01500.x.

7.

Integrin-linked kinase regulates vasomotor function by preventing endothelial nitric oxide synthase uncoupling: role in atherosclerosis.

Herranz B, Marquez S, Guijarro B, Aracil E, Aicart-Ramos C, Rodriguez-Crespo I, Serrano I, Rodríguez-Puyol M, Zaragoza C, Saura M.

Circ Res. 2012 Feb 3;110(3):439-49. doi: 10.1161/CIRCRESAHA.111.253948. Epub 2011 Dec 22. Erratum in: Circ Res. 2012 Mar 30;110(7):e48. Serrano, Isabel [added].

8.

Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin.

Laursen JB, Somers M, Kurz S, McCann L, Warnholtz A, Freeman BA, Tarpey M, Fukai T, Harrison DG.

Circulation. 2001 Mar 6;103(9):1282-8.

9.

BRCA1 is a novel target to improve endothelial dysfunction and retard atherosclerosis.

Singh KK, Shukla PC, Quan A, Al-Omran M, Lovren F, Pan Y, Brezden-Masley C, Ingram AJ, Stanford WL, Teoh H, Verma S.

J Thorac Cardiovasc Surg. 2013 Oct;146(4):949-960.e4. doi: 10.1016/j.jtcvs.2012.12.064. Epub 2013 Feb 14.

10.

Mononuclear cell therapy attenuates atherosclerosis in apoE KO mice.

Porto ML, Lima LC, Pereira TM, Nogueira BV, Tonini CL, Campagnaro BP, Meyrelles SS, Vasquez EC.

Lipids Health Dis. 2011 Sep 6;10:155. doi: 10.1186/1476-511X-10-155.

11.

Contribution of nitric oxide synthase isoforms to cholinergic vasodilation in murine retinal arterioles.

Gericke A, Goloborodko E, Sniatecki JJ, Steege A, Wojnowski L, Pfeiffer N.

Exp Eye Res. 2013 Apr;109:60-6. doi: 10.1016/j.exer.2013.01.012. Epub 2013 Feb 19.

PMID:
23434456
12.

Uncoupling of endothelial nitric oxidase synthase by hypochlorous acid: role of NAD(P)H oxidase-derived superoxide and peroxynitrite.

Xu J, Xie Z, Reece R, Pimental D, Zou MH.

Arterioscler Thromb Vasc Biol. 2006 Dec;26(12):2688-95. Epub 2006 Oct 5.

13.

CCR2-mediated antiinflammatory effects of endothelial tetrahydrobiopterin inhibit vascular injury-induced accelerated atherosclerosis.

Ali ZA, Bursill CA, Douglas G, McNeill E, Papaspyridonos M, Tatham AL, Bendall JK, Akhtar AM, Alp NJ, Greaves DR, Channon KM.

Circulation. 2008 Sep 30;118(14 Suppl):S71-7. doi: 10.1161/CIRCULATIONAHA.107.753558.

14.

Elevated systemic TGF-beta impairs aortic vasomotor function through activation of NADPH oxidase-driven superoxide production and leads to hypertension, myocardial remodeling, and increased plaque formation in apoE(-/-) mice.

Buday A, Orsy P, Godó M, Mózes M, Kökény G, Lacza Z, Koller A, Ungvári Z, Gross ML, Benyó Z, Hamar P.

Am J Physiol Heart Circ Physiol. 2010 Aug;299(2):H386-95. doi: 10.1152/ajpheart.01042.2009. Epub 2010 May 28.

15.

Tetrahydrobiopterin deficiency and nitric oxide synthase uncoupling contribute to atherosclerosis induced by disturbed flow.

Li L, Chen W, Rezvan A, Jo H, Harrison DG.

Arterioscler Thromb Vasc Biol. 2011 Jul;31(7):1547-54. doi: 10.1161/ATVBAHA.111.226456. Epub 2011 Apr 21.

16.
17.

Molecular mechanisms of activation of endothelial nitric oxide synthase mediated by transient receptor potential vanilloid type 1.

Ching LC, Kou YR, Shyue SK, Su KH, Wei J, Cheng LC, Yu YB, Pan CC, Lee TS.

Cardiovasc Res. 2011 Aug 1;91(3):492-501. doi: 10.1093/cvr/cvr104. Epub 2011 Apr 14.

18.

Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE-/- mice.

Judkins CP, Diep H, Broughton BR, Mast AE, Hooker EU, Miller AA, Selemidis S, Dusting GJ, Sobey CG, Drummond GR.

Am J Physiol Heart Circ Physiol. 2010 Jan;298(1):H24-32. doi: 10.1152/ajpheart.00799.2009. Epub 2009 Oct 16.

19.

5-methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling.

Antoniades C, Shirodaria C, Warrick N, Cai S, de Bono J, Lee J, Leeson P, Neubauer S, Ratnatunga C, Pillai R, Refsum H, Channon KM.

Circulation. 2006 Sep 12;114(11):1193-201. Epub 2006 Aug 28.

20.

Inactivity of nitric oxide synthase gene in the atherosclerotic human carotid artery.

Tanner FC, van der Loo B, Shaw S, Greutert H, Bachschmid MM, Berrozpe M, Rozenberg I, Blau N, Siebenmann R, Schmidli J, Meyer P, Lüscher TF.

Basic Res Cardiol. 2007 Jul;102(4):308-17. Epub 2007 Mar 15.

PMID:
17356797
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