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Items: 1 to 20 of 59

1.

Notch activation by the metalloproteinase ADAM17 regulates myeloproliferation and atopic barrier immunity by suppressing epithelial cytokine synthesis.

Murthy A, Shao YW, Narala SR, Molyneux SD, Zúñiga-Pflücker JC, Khokha R.

Immunity. 2012 Jan 27;36(1):105-19. doi: 10.1016/j.immuni.2012.01.005.

2.

The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling.

Weber S, Niessen MT, Prox J, Lüllmann-Rauch R, Schmitz A, Schwanbeck R, Blobel CP, Jorissen E, de Strooper B, Niessen CM, Saftig P.

Development. 2011 Feb;138(3):495-505. doi: 10.1242/dev.055210.

3.

TSLP expression: cellular sources, triggers, and regulatory mechanisms.

Takai T.

Allergol Int. 2012 Mar;61(1):3-17. doi: 10.2332/allergolint.11-RAI-0395. Epub 2012 Jan 25. Review.

4.

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation.

Franzke CW, Cobzaru C, Triantafyllopoulou A, Löffek S, Horiuchi K, Threadgill DW, Kurz T, van Rooijen N, Bruckner-Tuderman L, Blobel CP.

J Exp Med. 2012 Jun 4;209(6):1105-19. doi: 10.1084/jem.20112258. Epub 2012 May 7. Erratum in: J Exp Med. 2012 Dec 17;209(13):2517.

5.

Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling.

Bozkulak EC, Weinmaster G.

Mol Cell Biol. 2009 Nov;29(21):5679-95. doi: 10.1128/MCB.00406-09. Epub 2009 Aug 24.

6.

Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin.

Dumortier A, Durham AD, Di Piazza M, Vauclair S, Koch U, Ferrand G, Ferrero I, Demehri S, Song LL, Farr AG, Leonard WJ, Kopan R, Miele L, Hohl D, Finke D, Radtke F.

PLoS One. 2010 Feb 18;5(2):e9258. doi: 10.1371/journal.pone.0009258.

7.

The potential role of impaired Notch signalling in atopic dermatitis.

Melnik BC.

Acta Derm Venereol. 2015 Jan;95(1):5-11. doi: 10.2340/00015555-1898. Review.

8.

The ADAM family: Insights into Notch proteolysis.

Christian LM.

Fly (Austin). 2012 Jan-Mar;6(1):30-4. doi: 10.4161/fly.18823. Epub 2012 Jan 1. Review.

PMID:
22513479
9.

Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity.

Demehri S, Liu Z, Lee J, Lin MH, Crosby SD, Roberts CJ, Grigsby PW, Miner JH, Farr AG, Kopan R.

PLoS Biol. 2008 May 27;6(5):e123. doi: 10.1371/journal.pbio.0060123.

10.

Smooth muscle cells relay acute pulmonary inflammation via distinct ADAM17/ErbB axes.

Dreymueller D, Martin C, Schumacher J, Groth E, Boehm JK, Reiss LK, Uhlig S, Ludwig A.

J Immunol. 2014 Jan 15;192(2):722-31. doi: 10.4049/jimmunol.1302496. Epub 2013 Dec 16.

11.

Inducible deletion of the Blimp-1 gene in adult epidermis causes granulocyte-dominated chronic skin inflammation in mice.

Chiang MF, Yang SY, Lin IY, Hong JB, Lin SJ, Ying HY, Chen CM, Wu SY, Liu FT, Lin KI.

Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6476-81. doi: 10.1073/pnas.1219462110. Epub 2013 Apr 1.

12.

A disintegrin and metalloproteinase 17 (ADAM17) mediates inflammation-induced shedding of syndecan-1 and -4 by lung epithelial cells.

Pruessmeyer J, Martin C, Hess FM, Schwarz N, Schmidt S, Kogel T, Hoettecke N, Schmidt B, Sechi A, Uhlig S, Ludwig A.

J Biol Chem. 2010 Jan 1;285(1):555-64. doi: 10.1074/jbc.M109.059394. Epub 2009 Oct 29.

13.

Notch regulates IL-10 production by T helper 1 cells.

Rutz S, Janke M, Kassner N, Hohnstein T, Krueger M, Scheffold A.

Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3497-502. doi: 10.1073/pnas.0712102105. Epub 2008 Feb 21.

14.

Requirement of Notch activation during regeneration of the intestinal epithelia.

Okamoto R, Tsuchiya K, Nemoto Y, Akiyama J, Nakamura T, Kanai T, Watanabe M.

Am J Physiol Gastrointest Liver Physiol. 2009 Jan;296(1):G23-35. doi: 10.1152/ajpgi.90225.2008. Epub 2008 Nov 20.

15.

Notch signaling and the developing skin epidermis.

Massi D, Panelos J.

Adv Exp Med Biol. 2012;727:131-41. doi: 10.1007/978-1-4614-0899-4_10. Review.

PMID:
22399344
16.

Epidermal ADAM17 is dispensable for notch activation.

Groot AJ, Cobzaru C, Weber S, Saftig P, Blobel CP, Kopan R, Vooijs M, Franzke CW.

J Invest Dermatol. 2013 Sep;133(9):2286-8. doi: 10.1038/jid.2013.162. Epub 2013 Apr 3. No abstract available.

17.

IKK1 control of epidermal differentiation is modulated by notch signaling.

Xin Y, Lu Q, Li Q.

Am J Pathol. 2011 Apr;178(4):1568-77. doi: 10.1016/j.ajpath.2010.12.021.

18.

Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma.

Nickoloff BJ, Qin JZ, Chaturvedi V, Denning MF, Bonish B, Miele L.

Cell Death Differ. 2002 Aug;9(8):842-55.

19.

RBP-Jκ-dependent Notch signaling enhances retinal pigment epithelial cell proliferation in transgenic mice.

Schouwey K, Aydin IT, Radtke F, Beermann F.

Oncogene. 2011 Jan 20;30(3):313-22. doi: 10.1038/onc.2010.428. Epub 2010 Sep 20.

PMID:
20856205
20.

Inhibition of ADAM17 reduces hypoxia-induced brain tumor cell invasiveness.

Zheng X, Jiang F, Katakowski M, Kalkanis SN, Hong X, Zhang X, Zhang ZG, Yang H, Chopp M.

Cancer Sci. 2007 May;98(5):674-84. Epub 2007 Mar 9.

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