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Items: 1 to 20 of 107


Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs.

Sharifpoor S, van Dyk D, Costanzo M, Baryshnikova A, Friesen H, Douglas AC, Youn JY, VanderSluis B, Myers CL, Papp B, Boone C, Andrews BJ.

Genome Res. 2012 Apr;22(4):791-801. doi: 10.1101/gr.129213.111. Epub 2012 Jan 26.


The genetic landscape of a cell.

Costanzo M, Baryshnikova A, Bellay J, Kim Y, Spear ED, Sevier CS, Ding H, Koh JL, Toufighi K, Mostafavi S, Prinz J, St Onge RP, VanderSluis B, Makhnevych T, Vizeacoumar FJ, Alizadeh S, Bahr S, Brost RL, Chen Y, Cokol M, Deshpande R, Li Z, Lin ZY, Liang W, Marback M, Paw J, San Luis BJ, Shuteriqi E, Tong AH, van Dyk N, Wallace IM, Whitney JA, Weirauch MT, Zhong G, Zhu H, Houry WA, Brudno M, Ragibizadeh S, Papp B, Pál C, Roth FP, Giaever G, Nislow C, Troyanskaya OG, Bussey H, Bader GD, Gingras AC, Morris QD, Kim PM, Kaiser CA, Myers CL, Andrews BJ, Boone C.

Science. 2010 Jan 22;327(5964):425-31. doi: 10.1126/science.1180823.


Transcriptional regulatory networks in Saccharomyces cerevisiae.

Lee TI, Rinaldi NJ, Robert F, Odom DT, Bar-Joseph Z, Gerber GK, Hannett NM, Harbison CT, Thompson CM, Simon I, Zeitlinger J, Jennings EG, Murray HL, Gordon DB, Ren B, Wyrick JJ, Tagne JB, Volkert TL, Fraenkel E, Gifford DK, Young RA.

Science. 2002 Oct 25;298(5594):799-804.


Genetic networks inducing invasive growth in Saccharomyces cerevisiae identified through systematic genome-wide overexpression.

Shively CA, Eckwahl MJ, Dobry CJ, Mellacheruvu D, Nesvizhskii A, Kumar A.

Genetics. 2013 Apr;193(4):1297-310. doi: 10.1534/genetics.112.147876. Epub 2013 Feb 14.


Finding friends and enemies in an enemies-only network: a graph diffusion kernel for predicting novel genetic interactions and co-complex membership from yeast genetic interactions.

Qi Y, Suhail Y, Lin YY, Boeke JD, Bader JS.

Genome Res. 2008 Dec;18(12):1991-2004. doi: 10.1101/gr.077693.108. Epub 2008 Oct 2.


Illuminating transcription pathways using fluorescent reporter genes and yeast functional genomics.

Kainth P, Andrews B.

Transcription. 2010 Sep-Oct;1(2):76-80. doi: 10.4161/trns.1.2.12328.


Mapping pathways and phenotypes by systematic gene overexpression.

Sopko R, Huang D, Preston N, Chua G, Papp B, Kafadar K, Snyder M, Oliver SG, Cyert M, Hughes TR, Boone C, Andrews B.

Mol Cell. 2006 Feb 3;21(3):319-30.


Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell.

Magtanong L, Ho CH, Barker SL, Jiao W, Baryshnikova A, Bahr S, Smith AM, Heisler LE, Choy JS, Kuzmin E, Andrusiak K, Kobylianski A, Li Z, Costanzo M, Basrai MA, Giaever G, Nislow C, Andrews B, Boone C.

Nat Biotechnol. 2011 May 15;29(6):505-11. doi: 10.1038/nbt.1855.


Genome-wide association data reveal a global map of genetic interactions among protein complexes.

Hannum G, Srivas R, Guénolé A, van Attikum H, Krogan NJ, Karp RM, Ideker T.

PLoS Genet. 2009 Dec;5(12):e1000782. doi: 10.1371/journal.pgen.1000782. Epub 2009 Dec 24.


Mapping functional transcription factor networks from gene expression data.

Haynes BC, Maier EJ, Kramer MH, Wang PI, Brown H, Brent MR.

Genome Res. 2013 Aug;23(8):1319-28. doi: 10.1101/gr.150904.112. Epub 2013 May 1.


Unraveling networks of co-regulated genes on the sole basis of genome sequences.

Brohée S, Janky R, Abdel-Sater F, Vanderstocken G, André B, van Helden J.

Nucleic Acids Res. 2011 Aug;39(15):6340-58. doi: 10.1093/nar/gkr264. Epub 2011 May 13.


Genetic analysis of variation in transcription factor binding in yeast.

Zheng W, Zhao H, Mancera E, Steinmetz LM, Snyder M.

Nature. 2010 Apr 22;464(7292):1187-91. doi: 10.1038/nature08934. Epub 2010 Mar 17.


Linking high-resolution metabolic flux phenotypes and transcriptional regulation in yeast modulated by the global regulator Gcn4p.

Moxley JF, Jewett MC, Antoniewicz MR, Villas-Boas SG, Alper H, Wheeler RT, Tong L, Hinnebusch AG, Ideker T, Nielsen J, Stephanopoulos G.

Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6477-82. doi: 10.1073/pnas.0811091106. Epub 2009 Apr 3.


A general mechanism for network-dosage compensation in gene circuits.

Acar M, Pando BF, Arnold FH, Elowitz MB, van Oudenaarden A.

Science. 2010 Sep 24;329(5999):1656-60. doi: 10.1126/science.1190544.


Network-dosage compensation topologies as recurrent network motifs in natural gene networks.

Song R, Liu P, Acar M.

BMC Syst Biol. 2014 Jun 14;8:69. doi: 10.1186/1752-0509-8-69.


Chemical-genetic approaches for exploring the mode of action of natural products.

Lopez A, Parsons AB, Nislow C, Giaever G, Boone C.

Prog Drug Res. 2008;66:237, 239-71. Review.

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