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Results: 1 to 20 of 114

1.

Structure of complement C6 suggests a mechanism for initiation and unidirectional, sequential assembly of membrane attack complex (MAC).

Aleshin AE, Schraufstatter IU, Stec B, Bankston LA, Liddington RC, DiScipio RG.

J Biol Chem. 2012 Mar 23;287(13):10210-22. doi: 10.1074/jbc.M111.327809. Epub 2012 Jan 20.

PMID:
22267737
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Crystal structure of C5b-6 suggests structural basis for priming assembly of the membrane attack complex.

Aleshin AE, DiScipio RG, Stec B, Liddington RC.

J Biol Chem. 2012 Jun 1;287(23):19642-52. doi: 10.1074/jbc.M112.361121. Epub 2012 Apr 12.

PMID:
22500023
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.

Lovelace LL, Cooper CL, Sodetz JM, Lebioda L.

J Biol Chem. 2011 May 20;286(20):17585-92. doi: 10.1074/jbc.M111.219766. Epub 2011 Mar 25.

PMID:
21454577
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Incorporation of human complement C8 into the membrane attack complex is mediated by a binding site located within the C8beta MACPF domain.

Brannen CL, Sodetz JM.

Mol Immunol. 2007 Feb;44(5):960-5. Epub 2006 Apr 19.

PMID:
16624411
[PubMed - indexed for MEDLINE]
5.
6.

Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.

Hadders MA, Bubeck D, Roversi P, Hakobyan S, Forneris F, Morgan BP, Pangburn MK, Llorca O, Lea SM, Gros P.

Cell Rep. 2012 Mar 29;1(3):200-7. doi: 10.1016/j.celrep.2012.02.003. Epub 2012 Feb 23.

PMID:
22832194
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Functional studies of the MACPF domain of human complement protein C8alpha reveal sites for simultaneous binding of C8beta, C8gamma, and C9.

Slade DJ, Chiswell B, Sodetz JM.

Biochemistry. 2006 Apr 25;45(16):5290-6.

PMID:
16618117
[PubMed - indexed for MEDLINE]
8.

Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit.

Slade DJ, Lovelace LL, Chruszcz M, Minor W, Lebioda L, Sodetz JM.

J Mol Biol. 2008 May 30;379(2):331-42. doi: 10.1016/j.jmb.2008.03.061. Epub 2008 Apr 3.

PMID:
18440555
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Cholesterol-dependent cytolysins.

Gilbert RJ.

Adv Exp Med Biol. 2010;677:56-66. Review.

PMID:
20687480
[PubMed - indexed for MEDLINE]
10.

Crystal structure of complement protein C8gamma in complex with a peptide containing the C8gamma binding site on C8alpha: implications for C8gamma ligand binding.

Lovelace LL, Chiswell B, Slade DJ, Sodetz JM, Lebioda L.

Mol Immunol. 2008 Feb;45(3):750-6. Epub 2007 Aug 9.

PMID:
17692377
[PubMed - indexed for MEDLINE]
11.

Structure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense.

Hadders MA, Beringer DX, Gros P.

Science. 2007 Sep 14;317(5844):1552-4.

PMID:
17872444
[PubMed - indexed for MEDLINE]
Free Article
12.

Cloning of the sixth complement component and, spatial and temporal expression profile of MAC structural and regulatory genes in chicken.

Mikrou A, Zarkadis IK.

Dev Comp Immunol. 2010 May;34(5):485-90. doi: 10.1016/j.dci.2010.01.003. Epub 2010 Jan 17.

PMID:
20067805
[PubMed - indexed for MEDLINE]
13.

Binding of human complement C8 to C9: role of the N-terminal modules in the C8 alpha subunit.

Scibek JJ, Plumb ME, Sodetz JM.

Biochemistry. 2002 Dec 10;41(49):14546-51.

PMID:
12463754
[PubMed - indexed for MEDLINE]
14.

Molecular composition of the tubular structure of the membrane attack complex of complement.

Podack ER.

J Biol Chem. 1984 Jul 10;259(13):8641-7.

PMID:
6736043
[PubMed - indexed for MEDLINE]
Free Article
15.

Phylogenetic analysis of the homologous proteins of the terminal complement complex supports the emergence of C6 and C7 followed by C8 and C9.

Mondragón-Palomino M, Piñero D, Nicholson-Weller A, Laclette JP.

J Mol Evol. 1999 Aug;49(2):282-9.

PMID:
10441679
[PubMed - indexed for MEDLINE]
16.

Membrane pore formation by human complement: functional importance of the transmembrane β-hairpin (TMH) segments of C8α and C9.

Weiland MH, Qian Y, Sodetz JM.

Mol Immunol. 2014 Feb;57(2):310-6. doi: 10.1016/j.molimm.2013.10.007. Epub 2013 Nov 12.

PMID:
24239861
[PubMed - indexed for MEDLINE]
17.

Membrane attack complex of complement: generation of high-affinity phospholipid binding sites by fusion of five hydrophilic plasma proteins.

Podack ER, Biesecker G, Müller-Eberhard HJ.

Proc Natl Acad Sci U S A. 1979 Feb;76(2):897-901.

PMID:
284414
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Membrane attack by complement.

Podack ER, Tschopp J.

Mol Immunol. 1984 Jul;21(7):589-603. Review.

PMID:
6379417
[PubMed - indexed for MEDLINE]
19.

Membrane attack complex of complement: a structural analysis of its assembly.

Podack ER, Esser AF, Biesecker G, Müller-Eberhard HJ.

J Exp Med. 1980 Feb 1;151(2):301-13.

PMID:
7356725
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

An indel within the C8 alpha subunit of human complement C8 mediates intracellular binding of C8 gamma and formation of C8 alpha-gamma.

Plumb ME, Sodetz JM.

Biochemistry. 2000 Oct 24;39(42):13078-83.

PMID:
11041874
[PubMed - indexed for MEDLINE]

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