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Items: 1 to 20 of 213

1.

Hematopoietic stem cell mobilizing agents G-CSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation.

Winkler IG, Pettit AR, Raggatt LJ, Jacobsen RN, Forristal CE, Barbier V, Nowlan B, Cisterne A, Bendall LJ, Sims NA, Lévesque JP.

Leukemia. 2012 Jul;26(7):1594-601. doi: 10.1038/leu.2012.17. Epub 2012 Jan 23.

PMID:
22266913
2.
3.

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs.

Winkler IG, Sims NA, Pettit AR, Barbier V, Nowlan B, Helwani F, Poulton IJ, van Rooijen N, Alexander KA, Raggatt LJ, Lévesque JP.

Blood. 2010 Dec 2;116(23):4815-28. doi: 10.1182/blood-2009-11-253534. Epub 2010 Aug 16.

4.

Mobilization of hematopoietic stem cells by depleting bone marrow macrophages.

Barbier V, Winkler IG, Lévesque JP.

Methods Mol Biol. 2012;904:117-38. doi: 10.1007/978-1-61779-943-3_11.

PMID:
22890928
5.

Granulocyte colony stimulating factor expands hematopoietic stem cells within the central but not endosteal bone marrow region.

Grassinger J, Williams B, Olsen GH, Haylock DN, Nilsson SK.

Cytokine. 2012 May;58(2):218-25. doi: 10.1016/j.cyto.2012.01.014. Epub 2012 Feb 16.

PMID:
22341722
6.

Sphingosine-1-phosphate facilitates trafficking of hematopoietic stem cells and their mobilization by CXCR4 antagonists in mice.

Juarez JG, Harun N, Thien M, Welschinger R, Baraz R, Pena AD, Pitson SM, Rettig M, DiPersio JF, Bradstock KF, Bendall LJ.

Blood. 2012 Jan 19;119(3):707-16. doi: 10.1182/blood-2011-04-348904. Epub 2011 Nov 2.

7.

B-lymphopoiesis is stopped by mobilizing doses of G-CSF and is rescued by overexpression of the anti-apoptotic protein Bcl2.

Winkler IG, Bendall LJ, Forristal CE, Helwani F, Nowlan B, Barbier V, Shen Y, Cisterne A, Sedger LM, Levesque JP.

Haematologica. 2013 Mar;98(3):325-33. doi: 10.3324/haematol.2012.069260. Epub 2012 Aug 28.

8.

HIF-1α is required for hematopoietic stem cell mobilization and 4-prolyl hydroxylase inhibitors enhance mobilization by stabilizing HIF-1α.

Forristal CE, Nowlan B, Jacobsen RN, Barbier V, Walkinshaw G, Walkley CR, Winkler IG, Levesque JP.

Leukemia. 2015 Jun;29(6):1366-78. doi: 10.1038/leu.2015.8. Epub 2015 Jan 12.

10.

Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist.

Broxmeyer HE, Orschell CM, Clapp DW, Hangoc G, Cooper S, Plett PA, Liles WC, Li X, Graham-Evans B, Campbell TB, Calandra G, Bridger G, Dale DC, Srour EF.

J Exp Med. 2005 Apr 18;201(8):1307-18.

11.

Effect of stem cell mobilization with cyclophosphamide plus granulocyte colony-stimulating factor on morphology of haematopoietic organs in mice.

Szumilas P, Barcew K, Baśkiewicz-Masiuk M, Wiszniewska B, Ratajczak MZ, Machaliński B.

Cell Prolif. 2005 Feb;38(1):47-61.

PMID:
15679866
12.

Effective mobilization of hematopoietic progenitor cells in G-CSF mobilization defective CD26-/- mice through AMD3100-induced disruption of the CXCL12-CXCR4 axis.

Paganessi LA, Walker AL, Tan LL, Holmes I, Rich E, Fung HC, Christopherson KW 2nd.

Exp Hematol. 2011 Mar;39(3):384-90. doi: 10.1016/j.exphem.2010.12.003. Epub 2010 Dec 17.

13.

Heparan sulfate mimetics can efficiently mobilize long-term hematopoietic stem cells.

Di Giacomo F, Lewandowski D, Cabannes E, Nancy-Portebois V, Petitou M, Fichelson S, Romeo PH.

Haematologica. 2012 Apr;97(4):491-9. doi: 10.3324/haematol.2011.047662. Epub 2011 Dec 16.

15.

A combination of granulocyte-colony-stimulating factor (G-CSF) and plerixafor mobilizes more primitive peripheral blood progenitor cells than G-CSF alone: results of a European phase II study.

Fruehauf S, Veldwijk MR, Seeger T, Schubert M, Laufs S, Topaly J, Wuchter P, Dillmann F, Eckstein V, Wenz F, Goldschmidt H, Ho AD, Calandra G.

Cytotherapy. 2009;11(8):992-1001. doi: 10.3109/14653240903121245.

PMID:
19929463
16.

Mobilization by either cyclophosphamide or granulocyte colony-stimulating factor transforms the bone marrow into a highly proteolytic environment.

Lévesque JP, Hendy J, Takamatsu Y, Williams B, Winkler IG, Simmons PJ.

Exp Hematol. 2002 May;30(5):440-9.

PMID:
12031650
17.

G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow.

Semerad CL, Christopher MJ, Liu F, Short B, Simmons PJ, Winkler I, Levesque JP, Chappel J, Ross FP, Link DC.

Blood. 2005 Nov 1;106(9):3020-7. Epub 2005 Jul 21.

19.

Autophagy is required for stem cell mobilization by G-CSF.

Leveque-El Mouttie L, Vu T, Lineburg KE, Kuns RD, Bagger FO, Teal BE, Lor M, Boyle GM, Bruedigam C, Mintern JD, Hill GR, MacDonald KP, Lane SW.

Blood. 2015 May 7;125(19):2933-6. doi: 10.1182/blood-2014-03-562660. Epub 2015 Mar 18.

20.
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