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Results: 1 to 20 of 50

1.

Autoimmunity, intestinal lymphoid hyperplasia, and defects in mucosal B-cell homeostasis in patients with PTEN hamartoma tumor syndrome.

Heindl M, Händel N, Ngeow J, Kionke J, Wittekind C, Kamprad M, Rensing-Ehl A, Ehl S, Reifenberger J, Loddenkemper C, Maul J, Hoffmeister A, Aretz S, Kiess W, Eng C, Uhlig HH.

Gastroenterology. 2012 May;142(5):1093-1096.e6. doi: 10.1053/j.gastro.2012.01.011. Epub 2012 Jan 20.

PMID:
22266152
[PubMed - indexed for MEDLINE]
2.

PTEN hamartoma tumor syndromes.

Blumenthal GM, Dennis PA.

Eur J Hum Genet. 2008 Nov;16(11):1289-300. doi: 10.1038/ejhg.2008.162. Epub 2008 Sep 10. Review.

PMID:
18781191
[PubMed - indexed for MEDLINE]
Free Article
3.

Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.

McCubrey JA, Steelman LS, Abrams SL, Lee JT, Chang F, Bertrand FE, Navolanic PM, Terrian DM, Franklin RA, D'Assoro AB, Salisbury JL, Mazzarino MC, Stivala F, Libra M.

Adv Enzyme Regul. 2006;46:249-79. Epub 2006 Jul 18.

PMID:
16854453
[PubMed - indexed for MEDLINE]
4.

Phosphatidylinositol 3'-kinase/AKT signaling is activated in medulloblastoma cell proliferation and is associated with reduced expression of PTEN.

Hartmann W, Digon-Söntgerath B, Koch A, Waha A, Endl E, Dani I, Denkhaus D, Goodyer CG, Sörensen N, Wiestler OD, Pietsch T.

Clin Cancer Res. 2006 May 15;12(10):3019-27.

PMID:
16707597
[PubMed - indexed for MEDLINE]
Free Article
6.

Beta catenin and cytokine pathway dysregulation in patients with manifestations of the "PTEN hamartoma tumor syndrome".

Galatola M, Paparo L, Duraturo F, Turano M, Rossi GB, Izzo P, De Rosa M.

BMC Med Genet. 2012 Apr 20;13:28. doi: 10.1186/1471-2350-13-28.

PMID:
22520842
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

PTEN, more than the AKT pathway.

Blanco-Aparicio C, Renner O, Leal JF, Carnero A.

Carcinogenesis. 2007 Jul;28(7):1379-86. Epub 2007 Mar 6. Review.

PMID:
17341655
[PubMed - indexed for MEDLINE]
Free Article
8.

Thyroid pathology in PTEN-hamartoma tumor syndrome: characteristic findings of a distinct entity.

Laury AR, Bongiovanni M, Tille JC, Kozakewich H, Nosé V.

Thyroid. 2011 Feb;21(2):135-44. doi: 10.1089/thy.2010.0226. Epub 2010 Dec 29.

PMID:
21190448
[PubMed - indexed for MEDLINE]
9.

E-cadherin inhibits tumor cell growth by suppressing PI3K/Akt signaling via β-catenin-Egr1-mediated PTEN expression.

Lau MT, Klausen C, Leung PC.

Oncogene. 2011 Jun 16;30(24):2753-66. doi: 10.1038/onc.2011.6. Epub 2011 Feb 7.

PMID:
21297666
[PubMed - indexed for MEDLINE]
10.

Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins.

Yoshimi A, Goyama S, Watanabe-Okochi N, Yoshiki Y, Nannya Y, Nitta E, Arai S, Sato T, Shimabe M, Nakagawa M, Imai Y, Kitamura T, Kurokawa M.

Blood. 2011 Mar 31;117(13):3617-28. doi: 10.1182/blood-2009-12-261602. Epub 2011 Feb 2.

PMID:
21289308
[PubMed - indexed for MEDLINE]
Free Article
11.

PTEN regulates angiogenesis through PI3K/Akt/VEGF signaling pathway in human pancreatic cancer cells.

Ma J, Sawai H, Ochi N, Matsuo Y, Xu D, Yasuda A, Takahashi H, Wakasugi T, Takeyama H.

Mol Cell Biochem. 2009 Nov;331(1-2):161-71. doi: 10.1007/s11010-009-0154-x. Epub 2009 May 13.

PMID:
19437103
[PubMed - indexed for MEDLINE]
12.

Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma.

Cloughesy TF, Yoshimoto K, Nghiemphu P, Brown K, Dang J, Zhu S, Hsueh T, Chen Y, Wang W, Youngkin D, Liau L, Martin N, Becker D, Bergsneider M, Lai A, Green R, Oglesby T, Koleto M, Trent J, Horvath S, Mischel PS, Mellinghoff IK, Sawyers CL.

PLoS Med. 2008 Jan 22;5(1):e8. doi: 10.1371/journal.pmed.0050008.

PMID:
18215105
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A comprehensive functional analysis of PTEN mutations: implications in tumor- and autism-related syndromes.

Rodríguez-Escudero I, Oliver MD, Andrés-Pons A, Molina M, Cid VJ, Pulido R.

Hum Mol Genet. 2011 Nov 1;20(21):4132-42. doi: 10.1093/hmg/ddr337. Epub 2011 Aug 9.

PMID:
21828076
[PubMed - indexed for MEDLINE]
Free Article
14.

IGF-1 mediates PTEN suppression and enhances cell invasion and proliferation via activation of the IGF-1/PI3K/Akt signaling pathway in pancreatic cancer cells.

Ma J, Sawai H, Matsuo Y, Ochi N, Yasuda A, Takahashi H, Wakasugi T, Funahashi H, Sato M, Takeyama H.

J Surg Res. 2010 May 1;160(1):90-101. doi: 10.1016/j.jss.2008.08.016. Epub 2008 Sep 13.

PMID:
19560785
[PubMed - indexed for MEDLINE]
15.

Changes related to phosphatidylinositol 3-kinase/Akt signaling in leiomyomas: possible involvement of glycogen synthase kinase 3alpha and cyclin D2 in the pathophysiology.

Karra L, Shushan A, Ben-Meir A, Rojansky N, Klein BY, Shveiky D, Levitzki R, Ben-Bassat H.

Fertil Steril. 2010 May 15;93(8):2646-51. doi: 10.1016/j.fertnstert.2009.03.100. Epub 2009 May 21.

PMID:
19464003
[PubMed - indexed for MEDLINE]
16.

Primary lung adenocarcinoma occurring in a PTEN related syndrome (Cowden's disease): routine EGFR sequencing also highlights two rare somatic mutations S768I and V769L.

Boespflug A, Couraud S, Bringuier PP, Isaac S, Gérinière L, Perrot E, Edery P, Durieu I, Souquet PJ.

Lung Cancer. 2013 Mar;79(3):318-20. doi: 10.1016/j.lungcan.2012.11.020. Epub 2012 Dec 20.

PMID:
23261230
[PubMed - indexed for MEDLINE]
17.

Protein kinase CK2/PTEN pathway plays a key role in platelet-activating factor-mediated murine anaphylactic shock.

Kang NI, Yoon HY, Kim HA, Kim KJ, Han MK, Lee YR, Hwang PH, Soh BY, Shin SJ, Im SY, Lee HK.

J Immunol. 2011 Jun 1;186(11):6625-32. doi: 10.4049/jimmunol.1100007. Epub 2011 Apr 29.

PMID:
21531890
[PubMed - indexed for MEDLINE]
Free Article
18.

Coexistence of the loss of heterozygosity at the PTEN locus and HER2 overexpression enhances the Akt activity thus leading to a negative progesterone receptor expression in breast carcinoma.

Tokunaga E, Oki E, Kimura Y, Yamanaka T, Egashira A, Nishida K, Koga T, Morita M, Kakeji Y, Maehara Y.

Breast Cancer Res Treat. 2007 Mar;101(3):249-57. Epub 2006 Sep 28.

PMID:
17006756
[PubMed - indexed for MEDLINE]
19.

PTEN sensitizes MDA-MB-468 cells to inhibition of MEK/Erk signaling for the blockade of cell proliferation.

Jang K, Kim M, Seo HS, Shin I.

Oncol Rep. 2010 Sep;24(3):787-93.

PMID:
20664988
[PubMed - indexed for MEDLINE]
20.

PI3K/PTEN signaling in tumorigenesis and angiogenesis.

Jiang BH, Liu LZ.

Biochim Biophys Acta. 2008 Jan;1784(1):150-8. Epub 2007 Sep 29. Review.

PMID:
17964232
[PubMed - indexed for MEDLINE]
Free Article

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