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Results: 1 to 20 of 155

1.

Membrane-tethered MUC1 mucin is phosphorylated by epidermal growth factor receptor in airway epithelial cells and associates with TLR5 to inhibit recruitment of MyD88.

Kato K, Lillehoj EP, Park YS, Umehara T, Hoffman NE, Madesh M, Kim KC.

J Immunol. 2012 Feb 15;188(4):2014-22. doi: 10.4049/jimmunol.1102405. Epub 2012 Jan 16.

PMID:
22250084
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

MUC1 regulates epithelial inflammation and apoptosis by PolyI:C through inhibition of Toll/IL-1 receptor-domain-containing adapter-inducing IFN-β (TRIF) recruitment to Toll-like receptor 3.

Kato K, Lillehoj EP, Kim KC.

Am J Respir Cell Mol Biol. 2014 Sep;51(3):446-54. doi: 10.1165/rcmb.2014-0018OC.

PMID:
24693944
[PubMed - indexed for MEDLINE]
3.

Human airway epithelial cells sense Pseudomonas aeruginosa infection via recognition of flagellin by Toll-like receptor 5.

Zhang Z, Louboutin JP, Weiner DJ, Goldberg JB, Wilson JM.

Infect Immun. 2005 Nov;73(11):7151-60.

PMID:
16239509
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Cutting edge: enhanced pulmonary clearance of Pseudomonas aeruginosa by Muc1 knockout mice.

Lu W, Hisatsune A, Koga T, Kato K, Kuwahara I, Lillehoj EP, Chen W, Cross AS, Gendler SJ, Gewirtz AT, Kim KC.

J Immunol. 2006 Apr 1;176(7):3890-4.

PMID:
16547220
[PubMed - indexed for MEDLINE]
Free Article
5.

TRIF mediates Toll-like receptor 5-induced signaling in intestinal epithelial cells.

Choi YJ, Im E, Chung HK, Pothoulakis C, Rhee SH.

J Biol Chem. 2010 Nov 26;285(48):37570-8. doi: 10.1074/jbc.M110.158394. Epub 2010 Sep 20.

PMID:
20855887
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Pseudomonas aeruginosa flagella activate airway epithelial cells through asialoGM1 and toll-like receptor 2 as well as toll-like receptor 5.

Adamo R, Sokol S, Soong G, Gomez MI, Prince A.

Am J Respir Cell Mol Biol. 2004 May;30(5):627-34. Epub 2003 Nov 7.

PMID:
14607814
[PubMed - indexed for MEDLINE]
7.

Flagellin acting via TLR5 is the major activator of key signaling pathways leading to NF-kappa B and proinflammatory gene program activation in intestinal epithelial cells.

Tallant T, Deb A, Kar N, Lupica J, de Veer MJ, DiDonato JA.

BMC Microbiol. 2004 Aug 23;4:33.

PMID:
15324458
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The p38 mitogen-activated protein kinase signaling pathway is coupled to Toll-like receptor 5 to mediate gene regulation in response to Pseudomonas aeruginosa infection in human airway epithelial cells.

Zhang Z, Reenstra W, Weiner DJ, Louboutin JP, Wilson JM.

Infect Immun. 2007 Dec;75(12):5985-92. Epub 2007 Oct 1.

PMID:
17908812
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A crucial role of Flagellin in the induction of airway mucus production by Pseudomonas aeruginosa.

Ben Mohamed F, Garcia-Verdugo I, Medina M, Balloy V, Chignard M, Ramphal R, Touqui L.

PLoS One. 2012;7(7):e39888. doi: 10.1371/journal.pone.0039888. Epub 2012 Jul 2. Erratum in: PLoS One. 2012;7(8): doi/10.1371/annotation/7718a413-90cf-4183-9eb0-3a1b7c5bcd83. Mohamed, Fatima Ben [corrected to Ben Mohamed, Fatima]..

PMID:
22768318
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Role of MyD88 in phosphatidylinositol 3-kinase activation by flagellin/toll-like receptor 5 engagement in colonic epithelial cells.

Rhee SH, Kim H, Moyer MP, Pothoulakis C.

J Biol Chem. 2006 Jul 7;281(27):18560-8. Epub 2006 Apr 27.

PMID:
16644730
[PubMed - indexed for MEDLINE]
Free Article
11.

PPARγ inhibits airway epithelial cell inflammatory response through a MUC1-dependent mechanism.

Park YS, Lillehoj EP, Kato K, Park CS, Kim KC.

Am J Physiol Lung Cell Mol Physiol. 2012 Apr 1;302(7):L679-87. doi: 10.1152/ajplung.00360.2011. Epub 2012 Jan 20.

PMID:
22268120
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

TLR5-mediated activation of p38 MAPK regulates epithelial IL-8 expression via posttranscriptional mechanism.

Yu Y, Zeng H, Lyons S, Carlson A, Merlin D, Neish AS, Gewirtz AT.

Am J Physiol Gastrointest Liver Physiol. 2003 Aug;285(2):G282-90. Epub 2003 Apr 17.

PMID:
12702497
[PubMed - indexed for MEDLINE]
Free Article
13.

Involvement of epidermal growth factor receptor-linked signaling responses in Pseudomonas fluorescens-infected alveolar epithelial cells.

Choi HJ, Seo CH, Park SH, Yang H, Do KH, Kim J, Kim HK, Chung DH, Ahn JH, Moon Y.

Infect Immun. 2011 May;79(5):1998-2005. doi: 10.1128/IAI.01232-10. Epub 2011 Feb 22.

PMID:
21343351
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

NEU1 sialidase expressed in human airway epithelia regulates epidermal growth factor receptor (EGFR) and MUC1 protein signaling.

Lillehoj EP, Hyun SW, Feng C, Zhang L, Liu A, Guang W, Nguyen C, Luzina IG, Atamas SP, Passaniti A, Twaddell WS, Puché AC, Wang LX, Cross AS, Goldblum SE.

J Biol Chem. 2012 Mar 9;287(11):8214-31. doi: 10.1074/jbc.M111.292888. Epub 2012 Jan 13.

PMID:
22247545
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Flagellin/TLR5 responses induce mucus hypersecretion by activating EGFR via an epithelial cell signaling cascades.

Yu H, Zhou X, Wen S, Xiao Q.

Exp Cell Res. 2012 Apr 1;318(6):723-31. doi: 10.1016/j.yexcr.2011.12.016. Epub 2011 Dec 27.

PMID:
22227411
[PubMed - indexed for MEDLINE]
16.

Pseudomonas aeruginosa LPS or flagellin are sufficient to activate TLR-dependent signaling in murine alveolar macrophages and airway epithelial cells.

Raoust E, Balloy V, Garcia-Verdugo I, Touqui L, Ramphal R, Chignard M.

PLoS One. 2009 Oct 6;4(10):e7259. doi: 10.1371/journal.pone.0007259.

PMID:
19806220
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Pseudomonas aeruginosa stimulates phosphorylation of the airway epithelial membrane glycoprotein Muc1 and activates MAP kinase.

Lillehoj EP, Kim H, Chun EY, Kim KC.

Am J Physiol Lung Cell Mol Physiol. 2004 Oct;287(4):L809-15. Epub 2004 Jun 25.

PMID:
15220114
[PubMed - indexed for MEDLINE]
Free Article
18.

Tanshinone IIA inhibits lipopolysaccharide-induced MUC1 overexpression in alveolar epithelial cells.

Zhang K, Wang J, Jiang H, Xu X, Wang S, Zhang C, Li Z, Gong X, Lu W.

Am J Physiol Cell Physiol. 2014 Jan 1;306(1):C59-65. doi: 10.1152/ajpcell.00070.2013. Epub 2013 Oct 23.

PMID:
24153432
[PubMed - indexed for MEDLINE]
Free Article
19.

The TLR2 ligand FSL-1 and the TLR5 ligand Flagellin mediate pro-inflammatory and pro-labour response via MyD88/TRAF6/NF-κB-dependent signalling.

Lim R, Barker G, Lappas M.

Am J Reprod Immunol. 2014 May;71(5):401-17. doi: 10.1111/aji.12229. Epub 2014 Mar 17.

PMID:
24635133
[PubMed - indexed for MEDLINE]
20.

Resistance to Pseudomonas aeruginosa chronic lung infection requires cystic fibrosis transmembrane conductance regulator-modulated interleukin-1 (IL-1) release and signaling through the IL-1 receptor.

Reiniger N, Lee MM, Coleman FT, Ray C, Golan DE, Pier GB.

Infect Immun. 2007 Apr;75(4):1598-608. Epub 2007 Feb 5.

PMID:
17283089
[PubMed - indexed for MEDLINE]
Free PMC Article
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