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Results: 1 to 20 of 93

1.

The ratio of S-adenosylmethione and S-adenosyl-homocysteine is increased in the brains of newborn rats in a model of valproic acid teratogenicity.

Semmler A, Frisch C, Smith D, Blom H, Linnebank M.

Toxicology. 2012 Mar 11;293(1-3):132-3. doi: 10.1016/j.tox.2012.01.001. Epub 2012 Jan 11. No abstract available.

PMID:
22248911
[PubMed - indexed for MEDLINE]
2.

Multiple point action mechanism of valproic acid-teratogenicity alleviated by folic acid, vitamin C, and N-acetylcysteine in chicken embryo model.

Hsieh CL, Wang HE, Tsai WJ, Peng CC, Peng RY.

Toxicology. 2012 Jan 27;291(1-3):32-42. doi: 10.1016/j.tox.2011.10.015. Epub 2011 Oct 25.

PMID:
22051200
[PubMed - indexed for MEDLINE]
3.

Valproate-induced developmental modifications maybe partially prevented by coadministration of folinic acid and S-adenosylmethionine.

Ubeda N, Alonso E, Martín-Rodríguez JC, Varela-Moreiras G, Puerta J, Pérez-Miguelsanz J.

Int J Dev Biol. 1996;Suppl 1:291S-292S. No abstract available.

PMID:
9087803
[PubMed - indexed for MEDLINE]
Free Article
4.

Evidence for a trigger function of valproic acid in xenobiotic-induced hepatotoxicity.

Klee S, Johanssen S, Ungemach FR.

Pharmacol Toxicol. 2000 Aug;87(2):89-95.

PMID:
10989947
[PubMed - indexed for MEDLINE]
5.

Acute valproate administration impairs methionine metabolism in rats.

Ubeda N, Alonso-Aperte E, Varela-Moreiras G.

J Nutr. 2002 Sep;132(9):2737-42.

PMID:
12221238
[PubMed - indexed for MEDLINE]
Free Article
6.

Ultrastructural investigation of the protective role of folic acid and vitamin E against toxic effects of valproic acid on maternal liver tissue during period of gestation.

Baran OP, Kervancioglu P, Akkus M, Nergiz Y.

Saudi Med J. 2006 Mar;27(3):407-9. No abstract available.

PMID:
16532111
[PubMed - indexed for MEDLINE]
7.

Teratogenic effects of diabetic conditions in chick heart in ovo and in micromass culture may be prevented by addition of vitamin C and folic acid.

Memon S, Pratten MK.

Reprod Toxicol. 2013 Jan;35:117-24. doi: 10.1016/j.reprotox.2012.10.007. Epub 2012 Oct 23.

PMID:
23099339
[PubMed - indexed for MEDLINE]
8.

Cytotoxicity of unsaturated metabolites of valproic acid and protection by vitamins C and E in glutathione-depleted rat hepatocytes.

Jurima-Romet M, Abbott FS, Tang W, Huang HS, Whitehouse LW.

Toxicology. 1996 Aug 1;112(1):69-85.

PMID:
8792850
[PubMed - indexed for MEDLINE]
9.

Effect of supplemental folic acid on valproic acid-induced embryotoxicity and tissue zinc levels in vivo.

Hansen DK, Grafton TF, Dial SL, Gehring TA, Siitonen PH.

Teratology. 1995 Nov;52(5):277-85.

PMID:
8838251
[PubMed - indexed for MEDLINE]
10.

Valproic acid in pregnancy: how much are we endangering the embryo and fetus?

Ornoy A.

Reprod Toxicol. 2009 Jul;28(1):1-10. doi: 10.1016/j.reprotox.2009.02.014. Epub 2009 Mar 13. Review.

PMID:
19490988
[PubMed - indexed for MEDLINE]
11.

N-Acetylcysteine, vitamin C and vitamin E diminish homocysteine thiolactone-induced apoptosis in human promyeloid HL-60 cells.

Huang RF, Huang SM, Lin BS, Hung CY, Lu HT.

J Nutr. 2002 Aug;132(8):2151-6.

PMID:
12163654
[PubMed - indexed for MEDLINE]
Free Article
12.

Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: a potential for a second generation drug to valproic acid.

Shimshoni JA, Yagen B, Pessah N, Wlodarczyk B, Finnell RH, Bialer M.

Epilepsia. 2008 Jul;49(7):1202-12. doi: 10.1111/j.1528-1167.2008.01624.x.

PMID:
18435754
[PubMed - indexed for MEDLINE]
14.

Pharmacologic evaluation of various metabolites and analogs of valproic acid: teratogenic potencies in mice.

Nau H, Löscher W.

Fundam Appl Toxicol. 1986 May;6(4):669-76.

PMID:
3086174
[PubMed - indexed for MEDLINE]
15.

Hydroxamic acid and fluorinated derivatives of valproic acid: anticonvulsant activity, neurotoxicity and teratogenicity.

Gravemann U, Volland J, Nau H.

Neurotoxicol Teratol. 2008 Sep-Oct;30(5):390-4. doi: 10.1016/j.ntt.2008.03.060. Epub 2008 Mar 19.

PMID:
18455366
[PubMed - indexed for MEDLINE]
16.

VPA-induced neural tube defects in mice. I. Altered metabolism of sulfur amino acids and glutathione.

Hishida R, Nau H.

Teratog Carcinog Mutagen. 1998;18(2):49-61.

PMID:
9704382
[PubMed - indexed for MEDLINE]
17.

Folic acid and pantothenic acid protection against valproic acid-induced neural tube defects in CD-1 mice.

Dawson JE, Raymond AM, Winn LM.

Toxicol Appl Pharmacol. 2006 Mar 1;211(2):124-32. Epub 2005 Aug 22.

PMID:
16112698
[PubMed - indexed for MEDLINE]
18.

Simultaneous folate intake may prevent adverse effect of valproic acid on neurulating nervous system.

Umur AS, Selcuki M, Bursali A, Umur N, Kara B, Vatansever HS, Duransoy YK.

Childs Nerv Syst. 2012 May;28(5):729-37. doi: 10.1007/s00381-011-1673-9. Epub 2012 Jan 14.

PMID:
22246336
[PubMed - indexed for MEDLINE]
19.

Valproic acid teratogenicity: demonstration that the biochemical mechanism differs from that of valproate hepatotoxicity.

Brown NA, Farmer PB, Coakley M.

Biochem Soc Trans. 1985 Feb;13(1):75-7. No abstract available.

PMID:
3922822
[PubMed - indexed for MEDLINE]
20.

Acute autonomic effects of vitamins and fats in male smokers.

Wright CI, Ruediger H, Kroner CI, Janssen BJ, Draijer R.

Eur J Clin Nutr. 2009 Feb;63(2):246-52. Epub 2007 Sep 26.

PMID:
17895912
[PubMed - indexed for MEDLINE]

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