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Resistin-like molecule-α regulates IL-13-induced chemokine production but not allergen-induced airway responses.

Munitz A, Cole ET, Karo-Atar D, Finkelman FD, Rothenberg ME.

Am J Respir Cell Mol Biol. 2012 May;46(5):703-13. doi: 10.1165/rcmb.2011-0391OC. Epub 2012 Jan 12.


Resistin-like molecule-beta is an allergen-induced cytokine with inflammatory and remodeling activity in the murine lung.

Mishra A, Wang M, Schlotman J, Nikolaidis NM, DeBrosse CW, Karow ML, Rothenberg ME.

Am J Physiol Lung Cell Mol Physiol. 2007 Aug;293(2):L305-13. Epub 2007 Jun 1.


Resistin-like molecule alpha enhances myeloid cell activation and promotes colitis.

Munitz A, Waddell A, Seidu L, Cole ET, Ahrens R, Hogan SP, Rothenberg ME.

J Allergy Clin Immunol. 2008 Dec;122(6):1200-1207.e1. doi: 10.1016/j.jaci.2008.10.017.


Alternatively activated macrophage-derived RELM-{alpha} is a negative regulator of type 2 inflammation in the lung.

Nair MG, Du Y, Perrigoue JG, Zaph C, Taylor JJ, Goldschmidt M, Swain GP, Yancopoulos GD, Valenzuela DM, Murphy A, Karow M, Stevens S, Pearce EJ, Artis D.

J Exp Med. 2009 Apr 13;206(4):937-52. doi: 10.1084/jem.20082048. Epub 2009 Apr 6. Erratum in: J Exp Med. 2009 May 11;206(5):1201.


Paired immunoglobulin-like receptor-B inhibits pulmonary fibrosis by suppressing profibrogenic properties of alveolar macrophages.

Karo-Atar D, Moshkovits I, Eickelberg O, Königshoff M, Munitz A.

Am J Respir Cell Mol Biol. 2013 Apr;48(4):456-64. doi: 10.1165/rcmb.2012-0329OC.


Resistin-like molecule alpha decreases glucose tolerance during intestinal inflammation.

Munitz A, Seidu L, Cole ET, Ahrens R, Hogan SP, Rothenberg ME.

J Immunol. 2009 Feb 15;182(4):2357-63. doi: 10.4049/jimmunol.0803130.


Cytokine regulation of mucus production in a model of allergic asthma.

Cohn L, Whittaker L, Niu N, Homer RJ.

Novartis Found Symp. 2002;248:201-13; discussion 213-20, 277-82.


Retnla overexpression attenuates allergic inflammation of the airway.

Lee MR, Shim D, Yoon J, Jang HS, Oh SW, Suh SH, Choi JH, Oh GT.

PLoS One. 2014 Nov 21;9(11):e112666. doi: 10.1371/journal.pone.0112666. eCollection 2014.


Distinct roles for IL-13 and IL-4 via IL-13 receptor alpha1 and the type II IL-4 receptor in asthma pathogenesis.

Munitz A, Brandt EB, Mingler M, Finkelman FD, Rothenberg ME.

Proc Natl Acad Sci U S A. 2008 May 20;105(20):7240-5. doi: 10.1073/pnas.0802465105. Epub 2008 May 14.


Endogenous IL-11 signaling is essential in Th2- and IL-13-induced inflammation and mucus production.

Lee CG, Hartl D, Matsuura H, Dunlop FM, Scotney PD, Fabri LJ, Nash AD, Chen NY, Tang CY, Chen Q, Homer RJ, Baca M, Elias JA.

Am J Respir Cell Mol Biol. 2008 Dec;39(6):739-46. doi: 10.1165/rcmb.2008-0053OC. Epub 2008 Jul 10.


IL-13 receptor α1 differentially regulates aeroallergen-induced lung responses.

Rothenberg ME, Wen T, Shik D, Cole ET, Mingler MM, Munitz A.

J Immunol. 2011 Nov 1;187(9):4873-80. doi: 10.4049/jimmunol.1004159. Epub 2011 Sep 28.


Resistin-like molecule-β (RELM-β) targets airways fibroblasts to effect remodelling in asthma: from mouse to man.

Fang CL, Yin LJ, Sharma S, Kierstein S, Wu HF, Eid G, Haczku A, Corrigan CJ, Ying S.

Clin Exp Allergy. 2015 May;45(5):940-52. doi: 10.1111/cea.12481.


Allergen-induced resistin-like molecule-α promotes esophageal epithelial cell hyperplasia in eosinophilic esophagitis.

Mavi P, Niranjan R, Dutt P, Zaidi A, Shukla JS, Korfhagen T, Mishra A.

Am J Physiol Gastrointest Liver Physiol. 2014 Sep 1;307(5):G499-507. doi: 10.1152/ajpgi.00141.2014. Epub 2014 Jul 3. Erratum in: Am J Physiol Gastrointest Liver Physiol. 2015 Aug 15;309(4):G281.


Alveolar macrophages stimulate enhanced cytokine production by pulmonary CD4+ T-lymphocytes in an exacerbation of murine chronic asthma.

Herbert C, Scott MM, Scruton KH, Keogh RP, Yuan KC, Hsu K, Siegle JS, Tedla N, Foster PS, Kumar RK.

Am J Pathol. 2010 Oct;177(4):1657-64. doi: 10.2353/ajpath.2010.100019. Epub 2010 Aug 19.


The Th2 cell cytokines IL-4 and IL-13 regulate found in inflammatory zone 1/resistin-like molecule alpha gene expression by a STAT6 and CCAAT/enhancer-binding protein-dependent mechanism.

Stütz AM, Pickart LA, Trifilieff A, Baumruker T, Prieschl-Strassmayr E, Woisetschläger M.

J Immunol. 2003 Feb 15;170(4):1789-96.


Expression and activation of the oxytocin receptor in airway smooth muscle cells: Regulation by TNFalpha and IL-13.

Amrani Y, Syed F, Huang C, Li K, Liu V, Jain D, Keslacy S, Sims MW, Baidouri H, Cooper PR, Zhao H, Siddiqui S, Brightling CE, Griswold D, Li L, Panettieri RA Jr.

Respir Res. 2010 Jul 29;11:104. doi: 10.1186/1465-9921-11-104.


Anti-inflammatory activity of inhaled IL-4 receptor-alpha antisense oligonucleotide in mice.

Karras JG, Crosby JR, Guha M, Tung D, Miller DA, Gaarde WA, Geary RS, Monia BP, Gregory SA.

Am J Respir Cell Mol Biol. 2007 Mar;36(3):276-85. Epub 2006 Sep 21.


IL-12 contributes to allergen-induced airway inflammation in experimental asthma.

Meyts I, Hellings PW, Hens G, Vanaudenaerde BM, Verbinnen B, Heremans H, Matthys P, Bullens DM, Overbergh L, Mathieu C, De Boeck K, Ceuppens JL.

J Immunol. 2006 Nov 1;177(9):6460-70.


IL-11 selectively inhibits aeroallergen-induced pulmonary eosinophilia and Th2 cytokine production.

Wang J, Homer RJ, Hong L, Cohn L, Lee CG, Jung S, Elias JA.

J Immunol. 2000 Aug 15;165(4):2222-31.

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