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Similar articles for PubMed (Select 22246237)


Increased PARP-1 association with DNA in alkylation damaged, PARP-inhibited mouse fibroblasts.

Kedar PS, Stefanick DF, Horton JK, Wilson SH.

Mol Cancer Res. 2012 Mar;10(3):360-8. doi: 10.1158/1541-7786.MCR-11-0477. Epub 2012 Jan 13.


Alkylation DNA damage in combination with PARP inhibition results in formation of S-phase-dependent double-strand breaks.

Heacock ML, Stefanick DF, Horton JK, Wilson SH.

DNA Repair (Amst). 2010 Aug 5;9(8):929-36. doi: 10.1016/j.dnarep.2010.05.007. Epub 2010 Jun 22.


Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses.

Horton JK, Stefanick DF, Gassman NR, Williams JG, Gabel SA, Cuneo MJ, Prasad R, Kedar PS, Derose EF, Hou EW, London RE, Wilson SH.

DNA Repair (Amst). 2013 Sep;12(9):774-85. doi: 10.1016/j.dnarep.2013.06.004. Epub 2013 Jul 18.


Poly(ADP-ribose) polymerase activity prevents signaling pathways for cell cycle arrest after DNA methylating agent exposure.

Horton JK, Stefanick DF, Naron JM, Kedar PS, Wilson SH.

J Biol Chem. 2005 Apr 22;280(16):15773-85. Epub 2005 Feb 7.


Sensitization to radiation and alkylating agents by inhibitors of poly(ADP-ribose) polymerase is enhanced in cells deficient in DNA double-strand break repair.

Löser DA, Shibata A, Shibata AK, Woodbine LJ, Jeggo PA, Chalmers AJ.

Mol Cancer Ther. 2010 Jun;9(6):1775-87. doi: 10.1158/1535-7163.MCT-09-1027. Epub 2010 Jun 8.


Interaction between PARP-1 and ATR in mouse fibroblasts is blocked by PARP inhibition.

Kedar PS, Stefanick DF, Horton JK, Wilson SH.

DNA Repair (Amst). 2008 Nov 1;7(11):1787-98. doi: 10.1016/j.dnarep.2008.07.006. Epub 2008 Aug 22.


p21CDKN1A participates in base excision repair by regulating the activity of poly(ADP-ribose) polymerase-1.

Cazzalini O, Donà F, Savio M, Tillhon M, Maccario C, Perucca P, Stivala LA, Scovassi AI, Prosperi E.

DNA Repair (Amst). 2010 Jun 4;9(6):627-35. doi: 10.1016/j.dnarep.2010.02.011. Epub 2010 Mar 19.


Hyperactivation of PARP triggers nonhomologous end-joining in repair-deficient mouse fibroblasts.

Gassman NR, Stefanick DF, Kedar PS, Horton JK, Wilson SH.

PLoS One. 2012;7(11):e49301. doi: 10.1371/journal.pone.0049301. Epub 2012 Nov 7.


Role of poly(ADP-ribose) polymerase-1 in the removal of UV-induced DNA lesions by nucleotide excision repair.

Robu M, Shah RG, Petitclerc N, Brind'Amour J, Kandan-Kulangara F, Shah GM.

Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1658-63. doi: 10.1073/pnas.1209507110. Epub 2013 Jan 14.


PARP inhibition during alkylation-induced genotoxic stress signals a cell cycle checkpoint response mediated by ATM.

Carrozza MJ, Stefanick DF, Horton JK, Kedar PS, Wilson SH.

DNA Repair (Amst). 2009 Nov 2;8(11):1264-72. doi: 10.1016/j.dnarep.2009.07.010. Epub 2009 Aug 31.


Mechanism of early biphasic activation of poly(ADP-ribose) polymerase-1 in response to ultraviolet B radiation.

Vodenicharov MD, Ghodgaonkar MM, Halappanavar SS, Shah RG, Shah GM.

J Cell Sci. 2005 Feb 1;118(Pt 3):589-99. Epub 2005 Jan 18.


Poly(ADP-ribose) contributes to an association between poly(ADP-ribose) polymerase-1 and xeroderma pigmentosum complementation group A in nucleotide excision repair.

King BS, Cooper KL, Liu KJ, Hudson LG.

J Biol Chem. 2012 Nov 16;287(47):39824-33. doi: 10.1074/jbc.M112.393504. Epub 2012 Oct 4.


HMGN1 protein regulates poly(ADP-ribose) polymerase-1 (PARP-1) self-PARylation in mouse fibroblasts.

Masaoka A, Gassman NR, Kedar PS, Prasad R, Hou EW, Horton JK, Bustin M, Wilson SH.

J Biol Chem. 2012 Aug 10;287(33):27648-58. doi: 10.1074/jbc.M112.370759. Epub 2012 Jun 26.


Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis.

Moubarak RS, Yuste VJ, Artus C, Bouharrour A, Greer PA, Menissier-de Murcia J, Susin SA.

Mol Cell Biol. 2007 Jul;27(13):4844-62. Epub 2007 Apr 30.


Overproduction of the poly(ADP-ribose) polymerase DNA-binding domain blocks alkylation-induced DNA repair synthesis in mammalian cells.

Molinete M, Vermeulen W, Bürkle A, Ménissier-de Murcia J, Küpper JH, Hoeijmakers JH, de Murcia G.

EMBO J. 1993 May;12(5):2109-17.


Predicting enhanced cell killing through PARP inhibition.

Horton JK, Wilson SH.

Mol Cancer Res. 2013 Jan;11(1):13-8. doi: 10.1158/1541-7786.MCR-12-0512. Epub 2012 Nov 27.


Requirement for NBS1 in the S phase checkpoint response to DNA methylation combined with PARP inhibition.

Horton JK, Stefanick DF, Zeng JY, Carrozza MJ, Wilson SH.

DNA Repair (Amst). 2011 Feb 7;10(2):225-34. doi: 10.1016/j.dnarep.2010.11.003. Epub 2010 Dec 3.

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