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Items: 1 to 20 of 366

1.

The yeast complex I equivalent NADH dehydrogenase rescues pink1 mutants.

Vilain S, Esposito G, Haddad D, Schaap O, Dobreva MP, Vos M, Van Meensel S, Morais VA, De Strooper B, Verstreken P.

PLoS Genet. 2012 Jan;8(1):e1002456. doi: 10.1371/journal.pgen.1002456. Epub 2012 Jan 5.

2.

Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission.

Liu W, Acín-Peréz R, Geghman KD, Manfredi G, Lu B, Li C.

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12920-4. doi: 10.1073/pnas.1107332108. Epub 2011 Jul 18.

3.

The PINK1/Parkin pathway regulates mitochondrial morphology.

Poole AC, Thomas RE, Andrews LA, McBride HM, Whitworth AJ, Pallanck LJ.

Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1638-43. doi: 10.1073/pnas.0709336105. Epub 2008 Jan 29.

4.

Alternative oxidase rescues mitochondria-mediated dopaminergic cell loss in Drosophila.

Humphrey DM, Parsons RB, Ludlow ZN, Riemensperger T, Esposito G, Verstreken P, Jacobs HT, Birman S, Hirth F.

Hum Mol Genet. 2012 Jun 15;21(12):2698-712. doi: 10.1093/hmg/dds096. Epub 2012 Mar 7.

5.

The complex I subunit NDUFA10 selectively rescues Drosophila pink1 mutants through a mechanism independent of mitophagy.

Pogson JH, Ivatt RM, Sanchez-Martinez A, Tufi R, Wilson E, Mortiboys H, Whitworth AJ.

PLoS Genet. 2014 Nov 20;10(11):e1004815. doi: 10.1371/journal.pgen.1004815. eCollection 2014 Nov.

6.

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin.

Clark IE, Dodson MW, Jiang C, Cao JH, Huh JR, Seol JH, Yoo SJ, Hay BA, Guo M.

Nature. 2006 Jun 29;441(7097):1162-6. Epub 2006 May 3.

PMID:
16672981
7.

Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria.

Liu S, Sawada T, Lee S, Yu W, Silverio G, Alapatt P, Millan I, Shen A, Saxton W, Kanao T, Takahashi R, Hattori N, Imai Y, Lu B.

PLoS Genet. 2012;8(3):e1002537. doi: 10.1371/journal.pgen.1002537. Epub 2012 Mar 1.

8.

The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila.

Deng H, Dodson MW, Huang H, Guo M.

Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14503-8. doi: 10.1073/pnas.0803998105. Epub 2008 Sep 17.

9.

PINK1-mediated phosphorylation of Parkin boosts Parkin activity in Drosophila.

Shiba-Fukushima K, Inoshita T, Hattori N, Imai Y.

PLoS Genet. 2014 Jun 5;10(6):e1004391. doi: 10.1371/journal.pgen.1004391. eCollection 2014 Jun.

10.

The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process.

Park J, Lee G, Chung J.

Biochem Biophys Res Commun. 2009 Jan 16;378(3):518-23. doi: 10.1016/j.bbrc.2008.11.086. Epub 2008 Dec 3.

PMID:
19056353
11.

The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila.

Imai Y, Kanao T, Sawada T, Kobayashi Y, Moriwaki Y, Ishida Y, Takeda K, Ichijo H, Lu B, Takahashi R.

PLoS Genet. 2010 Dec 2;6(12):e1001229. doi: 10.1371/journal.pgen.1001229.

12.

Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease.

Costa AC, Loh SH, Martins LM.

Cell Death Dis. 2013 Jan 17;4:e467. doi: 10.1038/cddis.2012.205.

13.

Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation.

Lutz AK, Exner N, Fett ME, Schlehe JS, Kloos K, Lämmermann K, Brunner B, Kurz-Drexler A, Vogel F, Reichert AS, Bouman L, Vogt-Weisenhorn D, Wurst W, Tatzelt J, Haass C, Winklhofer KF.

J Biol Chem. 2009 Aug 21;284(34):22938-51. doi: 10.1074/jbc.M109.035774. Epub 2009 Jun 22.

14.
15.

TRAP1 rescues PINK1 loss-of-function phenotypes.

Zhang L, Karsten P, Hamm S, Pogson JH, Müller-Rischart AK, Exner N, Haass C, Whitworth AJ, Winklhofer KF, Schulz JB, Voigt A.

Hum Mol Genet. 2013 Jul 15;22(14):2829-41. doi: 10.1093/hmg/ddt132. Epub 2013 Mar 21.

16.

The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway.

Poole AC, Thomas RE, Yu S, Vincow ES, Pallanck L.

PLoS One. 2010 Apr 7;5(4):e10054. doi: 10.1371/journal.pone.0010054.

17.

Ret rescues mitochondrial morphology and muscle degeneration of Drosophila Pink1 mutants.

Klein P, Müller-Rischart AK, Motori E, Schönbauer C, Schnorrer F, Winklhofer KF, Klein R.

EMBO J. 2014 Feb 18;33(4):341-55. doi: 10.1002/embj.201284290. Epub 2014 Jan 28. Erratum in: EMBO J. 2014 Apr 1:33(7):779.

18.

Silent information regulator 2 (Sir2) and Forkhead box O (FOXO) complement mitochondrial dysfunction and dopaminergic neuron loss in Drosophila PTEN-induced kinase 1 (PINK1) null mutant.

Koh H, Kim H, Kim MJ, Park J, Lee HJ, Chung J.

J Biol Chem. 2012 Apr 13;287(16):12750-8. doi: 10.1074/jbc.M111.337907. Epub 2012 Feb 29.

19.

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin.

Park J, Lee SB, Lee S, Kim Y, Song S, Kim S, Bae E, Kim J, Shong M, Kim JM, Chung J.

Nature. 2006 Jun 29;441(7097):1157-61. Epub 2006 May 3.

PMID:
16672980
20.

MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin.

Yun J, Puri R, Yang H, Lizzio MA, Wu C, Sheng ZH, Guo M.

Elife. 2014 Jun 4;3:e01958. doi: 10.7554/eLife.01958.

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