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Improved outcome after peripheral nerve injury in mice with increased levels of endogenous ω-3 polyunsaturated fatty acids.

Gladman SJ, Huang W, Lim SN, Dyall SC, Boddy S, Kang JX, Knight MM, Priestley JV, Michael-Titus AT.

J Neurosci. 2012 Jan 11;32(2):563-71. doi: 10.1523/JNEUROSCI.3371-11.2012.


Transgenic mice with high endogenous omega-3 fatty acids are protected from spinal cord injury.

Lim SN, Gladman SJ, Dyall SC, Patel U, Virani N, Kang JX, Priestley JV, Michael-Titus AT.

Neurobiol Dis. 2013 Mar;51:104-12. doi: 10.1016/j.nbd.2012.10.021. Epub 2012 Nov 2.


Omega-3 fatty acids improve recovery, whereas omega-6 fatty acids worsen outcome, after spinal cord injury in the adult rat.

King VR, Huang WL, Dyall SC, Curran OE, Priestley JV, Michael-Titus AT.

J Neurosci. 2006 Apr 26;26(17):4672-80.


Endogenous ω-3 polyunsaturated fatty acid production confers resistance to obesity, dyslipidemia, and diabetes in mice.

Li J, Li FR, Wei D, Jia W, Kang JX, Stefanovic-Racic M, Dai Y, Zhao AZ.

Mol Endocrinol. 2014 Aug;28(8):1316-28. doi: 10.1210/me.2014-1011. Epub 2014 Jun 30.


The generation of transgenic mice with fat1 and fad2 genes that have their own polyunsaturated fatty acid biosynthetic pathway.

Chen Y, Mei M, Zhang P, Ma K, Song G, Ma X, Zhao T, Tang B, Ouyang H, Li G, Li Z.

Cell Physiol Biochem. 2013;32(3):523-32. doi: 10.1159/000354456. Epub 2013 Aug 30.


Omega-3 fatty acids and neurological injury.

Michael-Titus AT.

Prostaglandins Leukot Essent Fatty Acids. 2007 Nov-Dec;77(5-6):295-300. Epub 2007 Nov 26. Review.


Transgenic conversion of omega-6 into omega-3 fatty acids in a mouse model of Parkinson's disease.

Bousquet M, Gue K, Emond V, Julien P, Kang JX, Cicchetti F, Calon F.

J Lipid Res. 2011 Feb;52(2):263-71. doi: 10.1194/jlr.M011692. Epub 2010 Nov 29.


Prevention of reperfusion injury and microcirculatory failure in macrosteatotic mouse liver by omega-3 fatty acids.

El-Badry AM, Moritz W, Contaldo C, Tian Y, Graf R, Clavien PA.

Hepatology. 2007 Apr;45(4):855-63.


Dietary modulation of omega-3/omega-6 polyunsaturated fatty acid ratios in patients with breast cancer.

Bagga D, Capone S, Wang HJ, Heber D, Lill M, Chap L, Glaspy JA.

J Natl Cancer Inst. 1997 Aug 6;89(15):1123-31.


Omega-3 polyunsaturated fatty acids enhance cerebral angiogenesis and provide long-term protection after stroke.

Wang J, Shi Y, Zhang L, Zhang F, Hu X, Zhang W, Leak RK, Gao Y, Chen L, Chen J.

Neurobiol Dis. 2014 Aug;68:91-103. doi: 10.1016/j.nbd.2014.04.014. Epub 2014 Apr 29.


Omega-3 polyunsaturated fatty acids protect neural progenitor cells against oxidative injury.

Liu Q, Wu D, Ni N, Ren H, Luo C, He C, Kang JX, Wan JB, Su H.

Mar Drugs. 2014 Apr 29;12(5):2341-56. doi: 10.3390/md12052341.


Cox-2 expression, PGE(2) and cytokines production are inhibited by endogenously synthesized n-3 PUFAs in inflamed colon of fat-1 mice.

Gravaghi C, La Perle KM, Ogrodwski P, Kang JX, Quimby F, Lipkin M, Lamprecht SA.

J Nutr Biochem. 2011 Apr;22(4):360-5. doi: 10.1016/j.jnutbio.2010.03.003. Epub 2010 Jul 23.


Effects of adenoviral gene transfer of C. elegans n-3 fatty acid desaturase on the lipid profile and growth of human breast cancer cells.

Ge Y, Chen Z, Kang ZB, Cluette-Brown J, Laposata M, Kang JX.

Anticancer Res. 2002 Mar-Apr;22(2A):537-43.


Enriched endogenous omega-3 fatty acids in mice protect against global ischemia injury.

Luo C, Ren H, Wan JB, Yao X, Zhang X, He C, So KF, Kang JX, Pei Z, Su H.

J Lipid Res. 2014 May 29;55(7):1288-1297. [Epub ahead of print]


Transgenic overproduction of omega-3 polyunsaturated fatty acids provides neuroprotection and enhances endogenous neurogenesis after stroke.

Hu X, Zhang F, Leak RK, Zhang W, Iwai M, Stetler RA, Dai Y, Zhao A, Gao Y, Chen J.

Curr Mol Med. 2013 Nov;13(9):1465-73.


Omega-3 polyunsaturated fatty acid supplementation improves neurologic recovery and attenuates white matter injury after experimental traumatic brain injury.

Pu H, Guo Y, Zhang W, Huang L, Wang G, Liou AK, Zhang J, Zhang P, Leak RK, Wang Y, Chen J, Gao Y.

J Cereb Blood Flow Metab. 2013 Sep;33(9):1474-84. doi: 10.1038/jcbfm.2013.108. Epub 2013 Jun 26.


Dietary omega-3 polyunsaturated fatty acids improve the neurolipidome and restore the DHA status while promoting functional recovery after experimental spinal cord injury.

Figueroa JD, Cordero K, Llán MS, De Leon M.

J Neurotrauma. 2013 May 15;30(10):853-68. doi: 10.1089/neu.2012.2718. Epub 2013 Feb 6.


Dietary omega-3 and -6 polyunsaturated fatty acids affect the composition and development of sheep granulosa cells, oocytes and embryos.

Wonnacott KE, Kwong WY, Hughes J, Salter AM, Lea RG, Garnsworthy PC, Sinclair KD.

Reproduction. 2010 Jan;139(1):57-69. doi: 10.1530/REP-09-0219. Epub .


Fenretinide promotes functional recovery and tissue protection after spinal cord contusion injury in mice.

López-Vales R, Redensek A, Skinner TA, Rathore KI, Ghasemlou N, Wojewodka G, DeSanctis J, Radzioch D, David S.

J Neurosci. 2010 Mar 3;30(9):3220-6. doi: 10.1523/JNEUROSCI.5770-09.2010.

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