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Results: 1 to 20 of 98

1.

Direct short-term cytotoxic effects of BIBR 1532 on acute promyelocytic leukemia cells through induction of p21 coupled with downregulation of c-Myc and hTERT transcription.

Bashash D, Ghaffari SH, Zaker F, Hezave K, Kazerani M, Ghavamzadeh A, Alimoghaddam K, Mosavi SA, Gharehbaghian A, Vossough P.

Cancer Invest. 2012 Jan;30(1):57-64. doi: 10.3109/07357907.2011.629378.

PMID:
22236190
[PubMed - indexed for MEDLINE]
2.

Telomerase inhibition by non-nucleosidic compound BIBR1532 causes rapid cell death in pre-B acute lymphoblastic leukemia cells.

Bashash D, Ghaffari SH, Mirzaee R, Alimoghaddam K, Ghavamzadeh A.

Leuk Lymphoma. 2013 Mar;54(3):561-8. doi: 10.3109/10428194.2012.704034. Epub 2012 Sep 28.

PMID:
22957790
[PubMed - indexed for MEDLINE]
3.

BIBR 1532 increases arsenic trioxide-mediated apoptosis in acute promyelocytic leukemia cells: therapeutic potential for APL.

Bashash D, Ghaffari SH, Zaker F, Kazerani M, Hezave K, Hassani S, Rostami M, Alimoghaddam K, Ghavamzadeh A.

Anticancer Agents Med Chem. 2013 Sep;13(7):1115-25.

PMID:
23293885
[PubMed - indexed for MEDLINE]
4.

Cytotoxic effect of arsenic trioxide on acute promyelocytic leukemia cells through suppression of NFkβ-dependent induction of hTERT due to down-regulation of Pin1 transcription.

Ghaffari SH, Momeny M, Bashash D, Mirzaei R, Ghavamzadeh A, Alimoghaddam K.

Hematology. 2012 Jul;17(4):198-206. doi: 10.1179/1607845412Y.0000000008.

PMID:
22944098
[PubMed - indexed for MEDLINE]
5.

Butein suppresses c-Myc-dependent transcription and Akt-dependent phosphorylation of hTERT in human leukemia cells.

Moon DO, Kim MO, Lee JD, Choi YH, Kim GY.

Cancer Lett. 2009 Dec 28;286(2):172-9. doi: 10.1016/j.canlet.2009.05.028. Epub 2009 Jun 27.

PMID:
19560862
[PubMed - indexed for MEDLINE]
6.

Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells.

Huang ST, Wang CY, Yang RC, Chu CJ, Wu HT, Pang JH.

Phytomedicine. 2010 Jan;17(1):47-54. doi: 10.1016/j.phymed.2009.06.005. Epub 2009 Jul 3.

PMID:
19577445
[PubMed - indexed for MEDLINE]
7.
8.

Phenylarsine oxide (PAO) more intensely induces apoptosis in acute promyelocytic leukemia and As2O3-resistant APL cell lines than As2O3 by activating the mitochondrial pathway.

Sahara N, Takeshita A, Kobayashi M, Shigeno K, Nakamura S, Shinjo K, Naito K, Maekawa M, Horii T, Ohnishi K, Kitamura K, Naoe T, Hayash H, Ohno R.

Leuk Lymphoma. 2004 May;45(5):987-95.

PMID:
15291359
[PubMed - indexed for MEDLINE]
9.

Genistein represses telomerase activity via both transcriptional and posttranslational mechanisms in human prostate cancer cells.

Jagadeesh S, Kyo S, Banerjee PP.

Cancer Res. 2006 Feb 15;66(4):2107-15.

PMID:
16489011
[PubMed - indexed for MEDLINE]
Free Article
10.

Platycodin D induces apoptosis and decreases telomerase activity in human leukemia cells.

Kim MO, Moon DO, Choi YH, Shin DY, Kang HS, Choi BT, Lee JD, Li W, Kim GY.

Cancer Lett. 2008 Mar 8;261(1):98-107.

PMID:
18093727
[PubMed - indexed for MEDLINE]
11.

In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins.

Chen GQ, Zhu J, Shi XG, Ni JH, Zhong HJ, Si GY, Jin XL, Tang W, Li XS, Xong SM, Shen ZX, Sun GL, Ma J, Zhang P, Zhang TD, Gazin C, Naoe T, Chen SJ, Wang ZY, Chen Z.

Blood. 1996 Aug 1;88(3):1052-61.

PMID:
8704214
[PubMed - indexed for MEDLINE]
Free Article
12.

Gossypol suppresses telomerase activity in human leukemia cells via regulating hTERT.

Moon DO, Kim MO, Choi YH, Lee HG, Kim ND, Kim GY.

FEBS Lett. 2008 Oct 15;582(23-24):3367-73. doi: 10.1016/j.febslet.2008.08.029. Epub 2008 Sep 5.

PMID:
18775705
[PubMed - indexed for MEDLINE]
Free Article
13.

Apoptotic effect of oridonin on NB4 cells and its mechanism.

Liu J, Huang R, Lin D, Wu X, Peng J, Lin Q, Pan X, Zhang M, Hou M, Chen F.

Leuk Lymphoma. 2005 Apr;46(4):593-7.

PMID:
16019488
[PubMed - indexed for MEDLINE]
14.

Selective cytotoxicity and telomere damage in leukemia cells using the telomerase inhibitor BIBR1532.

El-Daly H, Kull M, Zimmermann S, Pantic M, Waller CF, Martens UM.

Blood. 2005 Feb 15;105(4):1742-9. Epub 2004 Oct 26.

PMID:
15507522
[PubMed - indexed for MEDLINE]
Free Article
15.

Notch signaling maintains proliferation and survival of the HL60 human promyelocytic leukemia cell line and promotes the phosphorylation of the Rb protein.

Li GH, Fan YZ, Liu XW, Zhang BF, Yin DD, He F, Huang SY, Kang ZJ, Xu H, Liu Q, Wu YL, Niu XL, Zhang L, Liu L, Hao MW, Han H, Liang YM.

Mol Cell Biochem. 2010 Jul;340(1-2):7-14. doi: 10.1007/s11010-010-0394-9. Epub 2010 Feb 16.

PMID:
20157766
[PubMed - indexed for MEDLINE]
16.

Sodium selenite induces apoptosis in acute promyelocytic leukemia-derived NB4 cells by a caspase-3-dependent mechanism and a redox pathway different from that of arsenic trioxide.

Zuo L, Li J, Yang Y, Wang X, Shen T, Xu CM, Zhang ZN.

Ann Hematol. 2004 Dec;83(12):751-8. Epub 2004 Oct 6.

PMID:
15480664
[PubMed - indexed for MEDLINE]
17.

Apoptosis of U937 human leukemic cells by sodium butyrate is associated with inhibition of telomerase activity.

Choi YH.

Int J Oncol. 2006 Nov;29(5):1207-13.

PMID:
17016653
[PubMed - indexed for MEDLINE]
18.

Overexpression of BP1, a homeobox gene, is associated with resistance to all-trans retinoic acid in acute promyelocytic leukemia cells.

Awwad RT, Do K, Stevenson H, Fu SW, Lo-Coco F, Costello M, Campbell CL, Berg PE.

Ann Hematol. 2008 Mar;87(3):195-203. Epub 2007 Nov 20.

PMID:
18026954
[PubMed - indexed for MEDLINE]
19.

Butylidenephthalide suppresses human telomerase reverse transcriptase (TERT) in human glioblastomas.

Lin PC, Lin SZ, Chen YL, Chang JS, Ho LI, Liu PY, Chang LF, Harn YC, Chen SP, Sun LY, Huang PC, Chein JT, Tsai CH, Chou CW, Harn HJ, Chiou TW.

Ann Surg Oncol. 2011 Nov;18(12):3514-27. doi: 10.1245/s10434-011-1644-0. Epub 2011 May 7.

PMID:
21553143
[PubMed - indexed for MEDLINE]
20.

Disabling c-Myc in childhood medulloblastoma and atypical teratoid/rhabdoid tumor cells by the potent G-quadruplex interactive agent S2T1-6OTD.

Shalaby T, von Bueren AO, Hürlimann ML, Fiaschetti G, Castelletti D, Masayuki T, Nagasawa K, Arcaro A, Jelesarov I, Shin-ya K, Grotzer M.

Mol Cancer Ther. 2010 Jan;9(1):167-79. doi: 10.1158/1535-7163.MCT-09-0586. Epub 2010 Jan 6.

PMID:
20053783
[PubMed - indexed for MEDLINE]
Free Article

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