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Items: 1 to 20 of 112

1.

Deep evolutionary conservation of an intramolecular protein kinase activation mechanism.

Han J, Miranda-Saavedra D, Luebbering N, Singh A, Sibbet G, Ferguson MA, Cleghon V.

PLoS One. 2012;7(1):e29702. doi: 10.1371/journal.pone.0029702. Epub 2012 Jan 3.

2.

Characterization of a domain that transiently converts class 2 DYRKs into intramolecular tyrosine kinases.

Kinstrie R, Luebbering N, Miranda-Saavedra D, Sibbet G, Han J, Lochhead PA, Cleghon V.

Sci Signal. 2010 Mar 2;3(111):ra16. doi: 10.1126/scisignal.2000579.

3.

Mechanism of dual specificity kinase activity of DYRK1A.

Walte A, Rüben K, Birner-Gruenberger R, Preisinger C, Bamberg-Lemper S, Hilz N, Bracher F, Becker W.

FEBS J. 2013 Sep;280(18):4495-511. doi: 10.1111/febs.12411. Epub 2013 Jul 22.

4.

Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs.

Lochhead PA, Sibbet G, Morrice N, Cleghon V.

Cell. 2005 Jun 17;121(6):925-36.

5.

dDYRK2: a novel dual-specificity tyrosine-phosphorylation-regulated kinase in Drosophila.

Lochhead PA, Sibbet G, Kinstrie R, Cleghon T, Rylatt M, Morrison DK, Cleghon V.

Biochem J. 2003 Sep 1;374(Pt 2):381-91.

6.

Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition.

Soundararajan M, Roos AK, Savitsky P, Filippakopoulos P, Kettenbach AN, Olsen JV, Gerber SA, Eswaran J, Knapp S, Elkins JM.

Structure. 2013 Jun 4;21(6):986-96. doi: 10.1016/j.str.2013.03.012. Epub 2013 May 9.

7.

Splice variants of the dual specificity tyrosine phosphorylation-regulated kinase 4 (DYRK4) differ in their subcellular localization and catalytic activity.

Papadopoulos C, Arato K, Lilienthal E, Zerweck J, Schutkowski M, Chatain N, Müller-Newen G, Becker W, de la Luna S.

J Biol Chem. 2011 Feb 18;286(7):5494-505. doi: 10.1074/jbc.M110.157909. Epub 2010 Dec 2.

8.

DYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 binding.

Alvarez M, Altafaj X, Aranda S, de la Luna S.

Mol Biol Cell. 2007 Apr;18(4):1167-78. Epub 2007 Jan 17.

9.

dDYRK2 and Minibrain interact with the chromatin remodelling factors SNR1 and TRX.

Kinstrie R, Lochhead PA, Sibbet G, Morrice N, Cleghon V.

Biochem J. 2006 Aug 15;398(1):45-54.

10.

DYRK family of protein kinases: evolutionary relationships, biochemical properties, and functional roles.

Aranda S, Laguna A, de la Luna S.

FASEB J. 2011 Feb;25(2):449-62. doi: 10.1096/fj.10-165837. Epub 2010 Nov 3. Review.

11.

Dyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIII.

Kentrup H, Becker W, Heukelbach J, Wilmes A, Schürmann A, Huppertz C, Kainulainen H, Joost HG.

J Biol Chem. 1996 Feb 16;271(7):3488-95.

12.

A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT.

Gwack Y, Sharma S, Nardone J, Tanasa B, Iuga A, Srikanth S, Okamura H, Bolton D, Feske S, Hogan PG, Rao A.

Nature. 2006 Jun 1;441(7093):646-50. Epub 2006 Mar 1.

PMID:
16511445
13.

Effect of tyrosine autophosphorylation on catalytic activity and subcellular localisation of homeodomain-interacting protein kinases (HIPK).

van der Laden J, Soppa U, Becker W.

Cell Commun Signal. 2015 Jan 29;13:3. doi: 10.1186/s12964-014-0082-6.

14.

Roles of the DYRK kinase Pom2 in cytokinesis, mitochondrial morphology, and sporulation in fission yeast.

Wu P, Zhao R, Ye Y, Wu JQ.

PLoS One. 2011;6(12):e28000. doi: 10.1371/journal.pone.0028000. Epub 2011 Dec 12.

15.

Phosphorylation of Ser640 in muscle glycogen synthase by DYRK family protein kinases.

Skurat AV, Dietrich AD.

J Biol Chem. 2004 Jan 23;279(4):2490-8. Epub 2003 Oct 30.

16.

Structural and functional characteristics of Dyrk, a novel subfamily of protein kinases with dual specificity.

Becker W, Joost HG.

Prog Nucleic Acid Res Mol Biol. 1999;62:1-17. Review.

PMID:
9932450
17.

Dyrk kinases regulate phosphorylation of doublecortin, cytoskeletal organization, and neuronal morphology.

Slepak TI, Salay LD, Lemmon VP, Bixby JL.

Cytoskeleton (Hoboken). 2012 Jul;69(7):514-27. doi: 10.1002/cm.21021. Epub 2012 Mar 7.

18.

Human homeodomain-interacting protein kinase-2 (HIPK2) is a member of the DYRK family of protein kinases and maps to chromosome 7q32-q34.

Hofmann TG, Mincheva A, Lichter P, Dröge W, Schmitz ML.

Biochimie. 2000 Dec;82(12):1123-7.

PMID:
11120354
19.

Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A.

Himpel S, Panzer P, Eirmbter K, Czajkowska H, Sayed M, Packman LC, Blundell T, Kentrup H, Grötzinger J, Joost HG, Becker W.

Biochem J. 2001 Nov 1;359(Pt 3):497-505.

20.

Dual-specificity tyrosine phosphorylation-regulated kinase 1A does not require tyrosine phosphorylation for activity in vitro.

Adayev T, Chen-Hwang MC, Murakami N, Lee E, Bolton DC, Hwang YW.

Biochemistry. 2007 Jun 26;46(25):7614-24. Epub 2007 May 31.

PMID:
17536841
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