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Impaired production of TNF-α by dendritic cells of older adults leads to a lower CD8+ T cell response against influenza.

Liu WM, Nahar TE, Jacobi RH, Gijzen K, van Beek J, Hak E, Jonges M, Boog CJ, van der Zeijst BA, Soethout EC.

Vaccine. 2012 Feb 21;30(9):1659-66. doi: 10.1016/j.vaccine.2011.12.105. Epub 2012 Jan 9.


Requirement of mature dendritic cells for efficient activation of influenza A-specific memory CD8+ T cells.

Larsson M, Messmer D, Somersan S, Fonteneau JF, Donahoe SM, Lee M, Dunbar PR, Cerundolo V, Julkunen I, Nixon DF, Bhardwaj N.

J Immunol. 2000 Aug 1;165(3):1182-90.


Strategies for antigen choice and priming of dendritic cells influence the polarization and efficacy of antitumor T-cell responses in dendritic cell-based cancer vaccination.

Galea-Lauri J, Wells JW, Darling D, Harrison P, Farzaneh F.

Cancer Immunol Immunother. 2004 Nov;53(11):963-77. Epub 2004 May 14.


Human CD8⁺ T cells drive Th1 responses through the differentiation of TNF/iNOS-producing dendritic cells.

Chong SZ, Wong KL, Lin G, Yang CM, Wong SC, Angeli V, Macary PA, Kemeny DM.

Eur J Immunol. 2011 Jun;41(6):1639-51. doi: 10.1002/eji.201041022. Epub 2011 May 9.


Dendritic cell inhibition is connected to exhaustion of CD8+ T cell polyfunctionality during chronic hepatitis C virus infection.

Rodrigue-Gervais IG, Rigsby H, Jouan L, Sauvé D, Sékaly RP, Willems B, Lamarre D.

J Immunol. 2010 Mar 15;184(6):3134-44. doi: 10.4049/jimmunol.0902522. Epub 2010 Feb 19.


HIV-1 Nef equips dendritic cells to reduce survival and function of CD8+ T cells: a mechanism of immune evasion.

Quaranta MG, Mattioli B, Giordani L, Viora M.

FASEB J. 2004 Sep;18(12):1459-61. Epub 2004 Jul 1.


IFN-alpha skews monocyte differentiation into Toll-like receptor 7-expressing dendritic cells with potent functional activities.

Mohty M, Vialle-Castellano A, Nunes JA, Isnardon D, Olive D, Gaugler B.

J Immunol. 2003 Oct 1;171(7):3385-93.


Human dendritic cells engineered to express alpha tumor necrosis factor maintain cellular maturation and T-cell stimulation capacity.

Ye Z, Chen Z, Sami A, El-Gayed A, Xiang J.

Cancer Biother Radiopharm. 2006 Dec;21(6):613-22.


Antitumour necrosis factor-alpha chimeric antibody (infliximab) inhibits activation of skin-homing CD4+ and CD8+ T lymphocytes and impairs dendritic cell function.

Bedini C, Nasorri F, Girolomoni G, Pità Od, Cavani A.

Br J Dermatol. 2007 Aug;157(2):249-58. Epub 2007 May 8.


The context of epitope presentation can influence functional quality of recalled influenza A virus-specific memory CD8+ T cells.

Day EB, Zeng W, Doherty PC, Jackson DC, Kedzierska K, Turner SJ.

J Immunol. 2007 Aug 15;179(4):2187-94.


Ageing impairs the T cell response to dendritic cells.

You J, Dong H, Mann ER, Knight SC, Yaqoob P.

Immunobiology. 2013 Aug;218(8):1077-84. doi: 10.1016/j.imbio.2013.02.002. Epub 2013 Mar 1.


Influenza virus evades innate and adaptive immunity via the NS1 protein.

Fernandez-Sesma A, Marukian S, Ebersole BJ, Kaminski D, Park MS, Yuen T, Sealfon SC, García-Sastre A, Moran TM.

J Virol. 2006 Jul;80(13):6295-304.


Dendritic cell gene therapy.

Onaitis M, Kalady MF, Pruitt S, Tyler DS.

Surg Oncol Clin N Am. 2002 Jul;11(3):645-60. Review.


Intratumoral injection of interferon-gamma gene-modified dendritic cells elicits potent antitumor effects: effective induction of tumor-specific CD8+ CTL response.

Pan J, Zhang M, Wang J, Wang Q, Xia D, Sun W, Zhang L, Yu H, Cao X.

J Cancer Res Clin Oncol. 2005 Jul;131(7):468-78. Epub 2005 Feb 12.


Suppression of choroidal neovascularization by dendritic cell vaccination targeting VEGFR2.

Mochimaru H, Nagai N, Hasegawa G, Kudo-Saito C, Yaguchi T, Usui Y, Kurihara T, Koto T, Satofuka S, Shinoda H, Ozawa Y, Tsubota K, Kawakami Y, Ishida S.

Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4795-801.


Monocyte-derived dendritic cells generated after a short-term culture with IFN-alpha and granulocyte-macrophage colony-stimulating factor stimulate a potent Epstein-Barr virus-specific CD8+ T cell response.

Santodonato L, D'Agostino G, Nisini R, Mariotti S, Monque DM, Spada M, Lattanzi L, Perrone MP, Andreotti M, Belardelli F, Ferrantini M.

J Immunol. 2003 May 15;170(10):5195-202.


Dendritic and T cell response to influenza is normal in the patients with X-linked agammaglobulinemia.

Liu Y, Wu Y, Lam KT, Lee PP, Tu W, Lau YL.

J Clin Immunol. 2012 Jun;32(3):421-9. doi: 10.1007/s10875-011-9639-y.


TLR signaling fine-tunes anti-influenza B cell responses without regulating effector T cell responses.

Heer AK, Shamshiev A, Donda A, Uematsu S, Akira S, Kopf M, Marsland BJ.

J Immunol. 2007 Feb 15;178(4):2182-91.


Role of cross-talk between IFN-alpha-induced monocyte-derived dendritic cells and NK cells in priming CD8+ T cell responses against human tumor antigens.

Tosi D, Valenti R, Cova A, Sovena G, Huber V, Pilla L, Arienti F, Belardelli F, Parmiani G, Rivoltini L.

J Immunol. 2004 May 1;172(9):5363-70.

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