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Results: 1 to 20 of 99

1.

Platelet-derived growth factor C deficiency in C57BL/6 mice leads to abnormal cerebral vascularization, loss of neuroependymal integrity, and ventricular abnormalities.

Fredriksson L, Nilsson I, Su EJ, Andrae J, Ding H, Betsholtz C, Eriksson U, Lawrence DA.

Am J Pathol. 2012 Mar;180(3):1136-44. doi: 10.1016/j.ajpath.2011.12.006. Epub 2012 Jan 9.

PMID:
22230248
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylation.

Tang Z, Arjunan P, Lee C, Li Y, Kumar A, Hou X, Wang B, Wardega P, Zhang F, Dong L, Zhang Y, Zhang SZ, Ding H, Fariss RN, Becker KG, Lennartsson J, Nagai N, Cao Y, Li X.

J Exp Med. 2010 Apr 12;207(4):867-80. doi: 10.1084/jem.20091704. Epub 2010 Mar 15.

PMID:
20231377
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Platelet-derived growth factor (PDGF)-C neutralization reveals differential roles of PDGF receptors in liver and kidney fibrosis.

Martin IV, Borkham-Kamphorst E, Zok S, van Roeyen CR, Eriksson U, Boor P, Hittatiya K, Fischer HP, Wasmuth HE, Weiskirchen R, Eitner F, Floege J, Ostendorf T.

Am J Pathol. 2013 Jan;182(1):107-17. doi: 10.1016/j.ajpath.2012.09.006. Epub 2012 Nov 7.

PMID:
23141925
[PubMed - indexed for MEDLINE]
Free Article
4.

A specific requirement for PDGF-C in palate formation and PDGFR-alpha signaling.

Ding H, Wu X, Boström H, Kim I, Wong N, Tsoi B, O'Rourke M, Koh GY, Soriano P, Betsholtz C, Hart TC, Marazita ML, Field LL, Tam PP, Nagy A.

Nat Genet. 2004 Oct;36(10):1111-6. Epub 2004 Sep 7.

PMID:
15361870
[PubMed - indexed for MEDLINE]
5.

PDGF-D is a potent transforming and angiogenic growth factor.

Li H, Fredriksson L, Li X, Eriksson U.

Oncogene. 2003 Mar 13;22(10):1501-10.

PMID:
12629513
[PubMed - indexed for MEDLINE]
6.

PDGF C is a selective alpha platelet-derived growth factor receptor agonist that is highly expressed in platelet alpha granules and vascular smooth muscle.

Fang L, Yan Y, Komuves LG, Yonkovich S, Sullivan CM, Stringer B, Galbraith S, Lokker NA, Hwang SS, Nurden P, Phillips DR, Giese NA.

Arterioscler Thromb Vasc Biol. 2004 Apr;24(4):787-92.

PMID:
15061151
[PubMed - indexed for MEDLINE]
Free Article
8.

Structural and functional specificities of PDGF-C and PDGF-D, the novel members of the platelet-derived growth factors family.

Reigstad LJ, Varhaug JE, Lillehaug JR.

FEBS J. 2005 Nov;272(22):5723-41. Review.

PMID:
16279938
[PubMed - indexed for MEDLINE]
Free Article
9.

Expression of platelet-derived growth factor (PDGF) in the epididymis and analysis of the epididymal development in PDGF-A, PDGF-B, and PDGF receptor beta deficient mice.

Basciani S, Mariani S, Arizzi M, Brama M, Ricci A, Betsholtz C, Bondjers C, Ricci G, Catizone A, Galdieri M, Spera G, Gnessi L.

Biol Reprod. 2004 Jan;70(1):168-77. Epub 2003 Oct 1.

PMID:
14522834
[PubMed - indexed for MEDLINE]
Free Article
10.

PDGF-DD, a novel mediator of smooth muscle cell phenotypic modulation, is upregulated in endothelial cells exposed to atherosclerosis-prone flow patterns.

Thomas JA, Deaton RA, Hastings NE, Shang Y, Moehle CW, Eriksson U, Topouzis S, Wamhoff BR, Blackman BR, Owens GK.

Am J Physiol Heart Circ Physiol. 2009 Feb;296(2):H442-52. doi: 10.1152/ajpheart.00165.2008. Epub 2008 Nov 21.

PMID:
19028801
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Effects of platelet-derived growth factor-AA and -BB on embryonic cardiac development.

Price RL, Haley ST, Bullard TA, Goldsmith EC, Simpson DG, Thielen TE, Yost MJ, Terracio L.

Anat Rec A Discov Mol Cell Evol Biol. 2003 May;272(1):424-33.

PMID:
12704700
[PubMed - indexed for MEDLINE]
Free Article
12.

A dual inhibitor of platelet-derived growth factor beta-receptor and Src kinase activity potently interferes with motogenic and mitogenic responses to PDGF in vascular smooth muscle cells. A novel candidate for prevention of vascular remodeling.

Waltenberger J, Uecker A, Kroll J, Frank H, Mayr U, Bjorge JD, Fujita D, Gazit A, Hombach V, Levitzki A, Böhmer FD.

Circ Res. 1999 Jul 9;85(1):12-22.

PMID:
10400906
[PubMed - indexed for MEDLINE]
Free Article
13.

Generation of conditional knockout alleles for PDGF-C.

Wu X, Ding H.

Genesis. 2007 Oct;45(10):653-7.

PMID:
17941048
[PubMed - indexed for MEDLINE]
14.

Oligodendrocyte progenitor cells promote neovascularization in glioma by disrupting the blood-brain barrier.

Huang Y, Hoffman C, Rajappa P, Kim JH, Hu W, Huse J, Tang Z, Li X, Weksler B, Bromberg J, Lyden DC, Greenfield JP.

Cancer Res. 2014 Feb 15;74(4):1011-21. doi: 10.1158/0008-5472.CAN-13-1072. Epub 2013 Dec 26.

PMID:
24371228
[PubMed - indexed for MEDLINE]
15.

Inhibition of platelet-derived growth factor actions in the embryonic testis influences normal cord development and morphology.

Uzumcu M, Dirks KA, Skinner MK.

Biol Reprod. 2002 Mar;66(3):745-53.

PMID:
11870082
[PubMed - indexed for MEDLINE]
Free Article
16.

Platelet-derived growth factor C (PDGF-C), a novel growth factor that binds to PDGF alpha and beta receptor.

Gilbertson DG, Duff ME, West JW, Kelly JD, Sheppard PO, Hofstrand PD, Gao Z, Shoemaker K, Bukowski TR, Moore M, Feldhaus AL, Humes JM, Palmer TE, Hart CE.

J Biol Chem. 2001 Jul 20;276(29):27406-14. Epub 2001 Apr 10.

PMID:
11297552
[PubMed - indexed for MEDLINE]
Free Article
17.

VEGF is major stimulator in model of choroidal neovascularization.

Kwak N, Okamoto N, Wood JM, Campochiaro PA.

Invest Ophthalmol Vis Sci. 2000 Sep;41(10):3158-64.

PMID:
10967078
[PubMed - indexed for MEDLINE]
Free Article
18.
19.

Transcription profiling of platelet-derived growth factor-B-deficient mouse embryos identifies RGS5 as a novel marker for pericytes and vascular smooth muscle cells.

Bondjers C, Kalén M, Hellström M, Scheidl SJ, Abramsson A, Renner O, Lindahl P, Cho H, Kehrl J, Betsholtz C.

Am J Pathol. 2003 Mar;162(3):721-9.

PMID:
12598306
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Defective oligodendrocyte development and severe hypomyelination in PDGF-A knockout mice.

Fruttiger M, Karlsson L, Hall AC, Abramsson A, Calver AR, Boström H, Willetts K, Bertold CH, Heath JK, Betsholtz C, Richardson WD.

Development. 1999 Feb;126(3):457-67.

PMID:
9876175
[PubMed - indexed for MEDLINE]
Free Article

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