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Results: 1 to 20 of 119

1.

Effects of aberrant Pax6 gene dosage on mouse corneal pathophysiology and corneal epithelial homeostasis.

Mort RL, Bentley AJ, Martin FL, Collinson JM, Douvaras P, Hill RE, Morley SD, Fullwood NJ, West JD.

PLoS One. 2011;6(12):e28895. doi: 10.1371/journal.pone.0028895. Epub 2011 Dec 29.

PMID:
22220198
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Increased corneal epithelial turnover contributes to abnormal homeostasis in the Pax6(+/-) mouse model of aniridia.

Douvaras P, Mort RL, Edwards D, Ramaesh K, Dhillon B, Morley SD, Hill RE, West JD.

PLoS One. 2013 Aug 13;8(8):e71117. doi: 10.1371/journal.pone.0071117. eCollection 2013.

PMID:
23967157
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Normal X-inactivation mosaicism in corneas of heterozygous FlnaDilp2/+ female mice--a model of human filamin A (FLNA) diseases.

Douvaras P, Liu W, Mort RL, McKie L, West KM, Cross SH, Morley SD, West JD.

BMC Res Notes. 2012 Feb 27;5:122. doi: 10.1186/1756-0500-5-122.

PMID:
22369496
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Developmental and cellular factors underlying corneal epithelial dysgenesis in the Pax6+/- mouse model of aniridia.

Ramaesh T, Ramaesh K, Martin Collinson J, Chanas SA, Dhillon B, West JD.

Exp Eye Res. 2005 Aug;81(2):224-35.

PMID:
16080917
[PubMed - indexed for MEDLINE]
5.

Corneal development, limbal stem cell function, and corneal epithelial cell migration in the Pax6(+/-) mouse.

Collinson JM, Chanas SA, Hill RE, West JD.

Invest Ophthalmol Vis Sci. 2004 Apr;45(4):1101-8.

PMID:
15037575
[PubMed - indexed for MEDLINE]
Free Article
6.

Increased apoptosis and abnormal wound-healing responses in the heterozygous Pax6+/- mouse cornea.

Ramaesh T, Ramaesh K, Leask R, Springbett A, Riley SC, Dhillon B, West JD.

Invest Ophthalmol Vis Sci. 2006 May;47(5):1911-7.

PMID:
16638998
[PubMed - indexed for MEDLINE]
Free Article
7.

Histopathological characterisation of effects of the mouse Pax6(Leca4) missense mutation on eye development.

Ramaesh T, Williams SE, Paul C, Ramaesh K, Dhillon B, West JD.

Exp Eye Res. 2009 Aug;89(2):263-73. doi: 10.1016/j.exer.2009.03.016. Epub 2009 Apr 2.

PMID:
19345209
[PubMed - indexed for MEDLINE]
8.

Interaction between hedgehog signalling and PAX6 dosage mediates maintenance and regeneration of the corneal epithelium.

Kucerova R, Dorà N, Mort RL, Wallace K, Leiper LJ, Lowes C, Neves C, Walczysko P, Bruce F, Fowler PA, Rajnicek AM, McCaig CD, Zhao M, West JD, Collinson JM.

Mol Vis. 2012;18:139-50. Epub 2012 Jan 18.

PMID:
22275805
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance.

Manuel M, Pratt T, Liu M, Jeffery G, Price DJ.

BMC Dev Biol. 2008 May 28;8:59. doi: 10.1186/1471-213X-8-59.

PMID:
18507827
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Effects of elevated Pax6 expression and genetic background on mouse eye development.

Chanas SA, Collinson JM, Ramaesh T, Dorà N, Kleinjan DA, Hill RE, West JD.

Invest Ophthalmol Vis Sci. 2009 Sep;50(9):4045-59. doi: 10.1167/iovs.07-1630. Epub 2009 Apr 22.

PMID:
19387074
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Corneal epithelial stem cells: deficiency and regulation.

Secker GA, Daniels JT.

Stem Cell Rev. 2008 Sep;4(3):159-68. doi: 10.1007/s12015-008-9029-x. Epub 2008 Jul 12. Review.

PMID:
18622724
[PubMed - indexed for MEDLINE]
12.

Overexpression of Pax6 in mouse cornea directly alters corneal epithelial cells: changes in immune function, vascularization, and differentiation.

Davis J, Piatigorsky J.

Invest Ophthalmol Vis Sci. 2011 Jun 13;52(7):4158-68. doi: 10.1167/iovs.10-6726.

PMID:
21447684
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Rare corneal clones in mice suggest an age-related decrease of stem cell activity and support the limbal epithelial stem cell hypothesis.

Douvaras P, Webb S, Whitaker DA, Dorà N, Hill RE, Dorin JR, West JD.

Stem Cell Res. 2012 Jan;8(1):109-19. doi: 10.1016/j.scr.2011.08.007. Epub 2011 Sep 5.

PMID:
22099025
[PubMed - indexed for MEDLINE]
14.

Corneal abnormalities in Pax6+/- small eye mice mimic human aniridia-related keratopathy.

Ramaesh T, Collinson JM, Ramaesh K, Kaufman MH, West JD, Dhillon B.

Invest Ophthalmol Vis Sci. 2003 May;44(5):1871-8.

PMID:
12714618
[PubMed - indexed for MEDLINE]
Free Article
15.

Cytoskeletal and cell adhesion defects in wounded and Pax6+/- corneal epithelia.

Ou J, Lowes C, Collinson JM.

Invest Ophthalmol Vis Sci. 2010 Mar;51(3):1415-23. doi: 10.1167/iovs.09-4023. Epub 2009 Nov 20.

PMID:
19933176
[PubMed - indexed for MEDLINE]
Free Article
16.

PAX6 dosage effects on corneal development, growth, and wound healing.

Dorà N, Ou J, Kucerova R, Parisi I, West JD, Collinson JM.

Dev Dyn. 2008 May;237(5):1295-306. doi: 10.1002/dvdy.21528.

PMID:
18386822
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization.

Manuel M, Georgala PA, Carr CB, Chanas S, Kleinjan DA, Martynoga B, Mason JO, Molinek M, Pinson J, Pratt T, Quinn JC, Simpson TI, Tyas DA, van Heyningen V, West JD, Price DJ.

Development. 2007 Feb;134(3):545-55. Epub 2007 Jan 3.

PMID:
17202185
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Chronic wound state exacerbated by oxidative stress in Pax6+/- aniridia-related keratopathy.

Ou J, Walczysko P, Kucerova R, Rajnicek AM, McCaig CD, Zhao M, Collinson JM.

J Pathol. 2008 Aug;215(4):421-30. doi: 10.1002/path.2371.

PMID:
18491289
[PubMed - indexed for MEDLINE]
19.

Intracorneal positioning of the lens in Pax6-GAL4/VP16 transgenic mice.

Govindarajan V, Harrison WR, Xiao N, Liang D, Overbeek PA.

Mol Vis. 2005 Oct 26;11:876-86.

PMID:
16270027
[PubMed - indexed for MEDLINE]
Free Article
20.

Control of patterns of corneal innervation by Pax6.

Leiper LJ, Ou J, Walczysko P, Kucerova R, Lavery DN, West JD, Collinson JM.

Invest Ophthalmol Vis Sci. 2009 Mar;50(3):1122-8. doi: 10.1167/iovs.08-2812. Epub 2008 Nov 21. Erratum in: Invest Ophthalmol Vis Sci. 2009 Jun;50(6):2580.

PMID:
19029029
[PubMed - indexed for MEDLINE]
Free PMC Article

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