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Items: 1 to 20 of 78

1.

MAPPIT as a high-throughput screening assay for modulators of protein-protein interactions in HIV and HCV.

Van Schoubroeck B, Van Acker K, Dams G, Jochmans D, Clayton R, Berke JM, Lievens S, Van der Heyden J, Tavernier J.

Methods Mol Biol. 2012;812:295-307. doi: 10.1007/978-1-61779-455-1_18.

PMID:
22218868
2.

MAPPIT (mammalian protein-protein interaction trap) analysis of early steps in toll-like receptor signalling.

Ulrichts P, Lemmens I, Lavens D, Beyaert R, Tavernier J.

Methods Mol Biol. 2009;517:133-44. doi: 10.1007/978-1-59745-541-1_9.

PMID:
19378012
3.

The use of mammalian two-hybrid technologies for high-throughput drug screening.

Lievens S, Caligiuri M, Kley N, Tavernier J.

Methods. 2012 Dec;58(4):335-42. doi: 10.1016/j.ymeth.2012.08.003. Epub 2012 Aug 14. Review.

PMID:
22917772
4.

Reverse MAPPIT detects disruptors of protein-protein interactions in human cells.

Lemmens I, Lievens S, Eyckerman S, Tavernier J.

Nat Protoc. 2006;1(1):92-7.

PMID:
17406217
5.

Design of a fluorescence-activated cell sorting-based Mammalian protein-protein interaction trap.

Lievens S, Van der Heyden J, Vertenten E, Plum J, Vandekerckhove J, Tavernier J.

Methods Mol Biol. 2004;263:293-310.

PMID:
14976373
6.

MAPPIT: a versatile tool to study cytokine receptor signalling.

Lemmens I, Lievens S, Tavernier J.

Biochem Soc Trans. 2008 Dec;36(Pt 6):1448-51. doi: 10.1042/BST0361448.

PMID:
19021573
7.

MAPPIT: a cytokine receptor-based two-hybrid method in mammalian cells.

Tavernier J, Eyckerman S, Lemmens I, Van der Heyden J, Vandekerckhove J, Van Ostade X.

Clin Exp Allergy. 2002 Oct;32(10):1397-404. Review.

PMID:
12372116
8.

High-throughput screening for modulators of protein-protein interactions: use of photonic crystal biosensors and complementary technologies.

Heeres JT, Hergenrother PJ.

Chem Soc Rev. 2011 Aug;40(8):4398-410. doi: 10.1039/b923660k. Epub 2010 Dec 7. Review.

PMID:
21140010
9.

Array MAPPIT: high-throughput interactome analysis in mammalian cells.

Lievens S, Vanderroost N, Van der Heyden J, Gesellchen V, Vidal M, Tavernier J.

J Proteome Res. 2009 Feb;8(2):877-86. doi: 10.1021/pr8005167.

PMID:
19159283
10.

ArrayMAPPIT: a screening platform for human protein interactome analysis.

Lievens S, Vanderroost N, Defever D, Van der Heyden J, Tavernier J.

Methods Mol Biol. 2012;812:283-94. doi: 10.1007/978-1-61779-455-1_17.

PMID:
22218867
11.

A cell-based high-throughput assay for the screening of small-molecule inhibitors of p53-MDM2 interaction.

Li J, Zhang S, Gao L, Chen Y, Xie X.

J Biomol Screen. 2011 Apr;16(4):450-6. doi: 10.1177/1087057111399191.

PMID:
21471462
12.

A reporter-based assay for identifying hepatitis C virus inhibitors based on subgenomic replicon cells.

Lee JC, Chang CF, Chi YH, Hwang DR, Hsu JT.

J Virol Methods. 2004 Mar 1;116(1):27-33.

PMID:
14715304
13.

Development of robust in vitro serine protease assay based on recombinant Pakistani HCV NS3-4A protease.

Fatima K, Tahir M, Qadri I.

Virus Res. 2011 Sep;160(1-2):230-7. doi: 10.1016/j.virusres.2011.06.020. Epub 2011 Jul 2.

PMID:
21756947
14.

Establishment of an in vitro assay system for screening hepatitis C virus protease inhibitors using high performance liquid chromatography.

Sudo K, Inoue H, Shimizu Y, Yamaji K, Konno K, Shigeta S, Kaneko T, Yokota T, Shimotohno K.

Antiviral Res. 1996 Aug;32(1):9-18.

PMID:
8863991
15.

Development of NS3/4A protease-based reporter assay suitable for efficiently assessing hepatitis C virus infection.

Pan KL, Lee JC, Sung HW, Chang TY, Hsu JT.

Antimicrob Agents Chemother. 2009 Nov;53(11):4825-34. doi: 10.1128/AAC.00601-09. Epub 2009 Aug 31.

16.

High-throughput screening of libraries of compounds to identify CFTR modulators.

Pedemonte N, Zegarra-Moran O, Galietta LJ.

Methods Mol Biol. 2011;741:13-21. doi: 10.1007/978-1-61779-117-8_2.

PMID:
21594775
17.

Development of filtration-based time-resolved fluorescence assay for the high-throughput screening of urotensin II receptor antagonist.

Oh KS, Lee S, Lee BH.

Assay Drug Dev Technol. 2011 Oct;9(5):514-21. doi: 10.1089/adt.2010.0353. Epub 2011 May 11.

PMID:
21561377
18.

High-throughput mammalian two-hybrid screening for protein-protein interactions using transfected cell arrays.

Fiebitz A, Nyarsik L, Haendler B, Hu YH, Wagner F, Thamm S, Lehrach H, Janitz M, Vanhecke D.

BMC Genomics. 2008 Feb 6;9:68. doi: 10.1186/1471-2164-9-68.

19.

A mammalian two-hybrid system-based assay for small-molecular HIV fusion inhibitors targeting gp41.

Shui X, Lu X, Gao Y, Liu C, Ren F, Jiang Q, Zhang H, Zhao B, Zheng Z.

Antiviral Res. 2011 Apr;90(1):54-63. doi: 10.1016/j.antiviral.2011.02.006. Epub 2011 Feb 23.

PMID:
21352856
20.

Preparation of HCV NS3 and NS5B proteins to support small-molecule drug discovery.

Hung M, Wang R, Liu X.

Curr Protoc Pharmacol. 2011 Sep;Chapter 13:Unit13B.6. doi: 10.1002/0471141755.ph13b06s54.

PMID:
21898331
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