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Items: 1 to 20 of 96

1.

The Mycobacterium tuberculosis FAS-II dehydratases and methyltransferases define the specificity of the mycolic acid elongation complexes.

Cantaloube S, Veyron-Churlet R, Haddache N, Daffé M, Zerbib D.

PLoS One. 2011;6(12):e29564. doi: 10.1371/journal.pone.0029564. Epub 2011 Dec 22.

2.

The biosynthesis of mycolic acids in Mycobacterium tuberculosis relies on multiple specialized elongation complexes interconnected by specific protein-protein interactions.

Veyron-Churlet R, Bigot S, Guerrini O, Verdoux S, Malaga W, Daffé M, Zerbib D.

J Mol Biol. 2005 Nov 4;353(4):847-58. Epub 2005 Sep 23.

PMID:
16213523
3.

The missing piece of the type II fatty acid synthase system from Mycobacterium tuberculosis.

Sacco E, Covarrubias AS, O'Hare HM, Carroll P, Eynard N, Jones TA, Parish T, Daffé M, Bäckbro K, Quémard A.

Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14628-33. Epub 2007 Sep 5.

4.

Revisiting the assignment of Rv0241c to fatty acid synthase type II of Mycobacterium tuberculosis.

Sacco E, Slama N, Bäckbro K, Parish T, Laval F, Daffé M, Eynard N, Quémard A.

J Bacteriol. 2010 Aug;192(15):4037-44. doi: 10.1128/JB.00386-10. Epub 2010 May 28.

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6.

Negative regulation by Ser/Thr phosphorylation of HadAB and HadBC dehydratases from Mycobacterium tuberculosis type II fatty acid synthase system.

Slama N, Leiba J, Eynard N, Daffé M, Kremer L, Quémard A, Molle V.

Biochem Biophys Res Commun. 2011 Sep 2;412(3):401-6. doi: 10.1016/j.bbrc.2011.07.051. Epub 2011 Jul 27.

PMID:
21819969
7.

Mycobacterium tuberculosis proteins involved in mycolic acid synthesis and transport localize dynamically to the old growing pole and septum.

Carel C, Nukdee K, Cantaloube S, Bonne M, Diagne CT, Laval F, Daffé M, Zerbib D.

PLoS One. 2014 May 9;9(5):e97148. doi: 10.1371/journal.pone.0097148. eCollection 2014.

8.

Identification of the dehydratase component of the mycobacterial mycolic acid-synthesizing fatty acid synthase-II complex.

Brown AK, Bhatt A, Singh A, Saparia E, Evans AF, Besra GS.

Microbiology. 2007 Dec;153(Pt 12):4166-73.

PMID:
18048930
9.

Point mutations within the fatty acid synthase type II dehydratase components HadA or HadC contribute to isoxyl resistance in Mycobacterium tuberculosis.

Gannoun-Zaki L, Alibaud L, Kremer L.

Antimicrob Agents Chemother. 2013 Jan;57(1):629-32. doi: 10.1128/AAC.01972-12. Epub 2012 Oct 31.

10.
11.

Mycolic acid biosynthesis and enzymic characterization of the beta-ketoacyl-ACP synthase A-condensing enzyme from Mycobacterium tuberculosis.

Kremer L, Dover LG, Carrère S, Nampoothiri KM, Lesjean S, Brown AK, Brennan PJ, Minnikin DE, Locht C, Besra GS.

Biochem J. 2002 Jun 1;364(Pt 2):423-30.

12.

ACCase 6 is the essential acetyl-CoA carboxylase involved in fatty acid and mycolic acid biosynthesis in mycobacteria.

Kurth DG, Gago GM, de la Iglesia A, Bazet Lyonnet B, Lin TW, Morbidoni HR, Tsai SC, Gramajo H.

Microbiology. 2009 Aug;155(Pt 8):2664-75. doi: 10.1099/mic.0.027714-0. Epub 2009 May 7.

13.

Purification and biochemical characterization of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthases KasA and KasB.

Schaeffer ML, Agnihotri G, Volker C, Kallender H, Brennan PJ, Lonsdale JT.

J Biol Chem. 2001 Dec 14;276(50):47029-37. Epub 2001 Oct 12.

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15.

The Molecular Genetics of Mycolic Acid Biosynthesis.

Pawełczyk J, Kremer L.

Microbiol Spectr. 2014 Aug;2(4):MGM2-0003-2013. doi: 10.1128/microbiolspec.MGM2-0003-2013. Review.

PMID:
26104214
16.

MabA (FabG1), a Mycobacterium tuberculosis protein involved in the long-chain fatty acid elongation system FAS-II.

Marrakchi H, Ducasse S, Labesse G, Montrozier H, Margeat E, Emorine L, Charpentier X, Daffé M, Quémard A.

Microbiology. 2002 Apr;148(Pt 4):951-60.

PMID:
11932442
17.

The condensing activities of the Mycobacterium tuberculosis type II fatty acid synthase are differentially regulated by phosphorylation.

Molle V, Brown AK, Besra GS, Cozzone AJ, Kremer L.

J Biol Chem. 2006 Oct 6;281(40):30094-103. Epub 2006 Jul 27.

18.

A common mechanism of inhibition of the Mycobacterium tuberculosis mycolic acid biosynthetic pathway by isoxyl and thiacetazone.

Grzegorzewicz AE, Korduláková J, Jones V, Born SE, Belardinelli JM, Vaquié A, Gundi VA, Madacki J, Slama N, Laval F, Vaubourgeix J, Crew RM, Gicquel B, Daffé M, Morbidoni HR, Brennan PJ, Quémard A, McNeil MR, Jackson M.

J Biol Chem. 2012 Nov 9;287(46):38434-41. doi: 10.1074/jbc.M112.400994. Epub 2012 Sep 21.

19.

Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis.

Takayama K, Wang C, Besra GS.

Clin Microbiol Rev. 2005 Jan;18(1):81-101. Review.

20.

Antimycobacterial action of thiolactomycin: an inhibitor of fatty acid and mycolic acid synthesis.

Slayden RA, Lee RE, Armour JW, Cooper AM, Orme IM, Brennan PJ, Besra GS.

Antimicrob Agents Chemother. 1996 Dec;40(12):2813-9.

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