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Items: 1 to 20 of 223

1.

Stable isotope-resolved metabolomics and applications for drug development.

Fan TW, Lorkiewicz PK, Sellers K, Moseley HN, Higashi RM, Lane AN.

Pharmacol Ther. 2012 Mar;133(3):366-91. doi: 10.1016/j.pharmthera.2011.12.007. Epub 2011 Dec 23. Review.

2.

Stable isotope-labeled tracers for metabolic pathway elucidation by GC-MS and FT-MS.

Higashi RM, Fan TW, Lorkiewicz PK, Moseley HN, Lane AN.

Methods Mol Biol. 2014;1198:147-67. doi: 10.1007/978-1-4939-1258-2_11.

3.

Elucidation of cellular metabolism via metabolomics and stable-isotope assisted metabolomics.

Hiller K, Metallo C, Stephanopoulos G.

Curr Pharm Biotechnol. 2011 Jul;12(7):1075-86. Review.

PMID:
21466455
4.

Prospects for clinical cancer metabolomics using stable isotope tracers.

Lane AN, Fan TW, Higashi RM, Tan J, Bousamra M, Miller DM.

Exp Mol Pathol. 2009 Jun;86(3):165-73. doi: 10.1016/j.yexmp.2009.01.005. Epub 2009 Jan 20. Review.

5.

15N-cholamine--a smart isotope tag for combining NMR- and MS-based metabolite profiling.

Tayyari F, Gowda GA, Gu H, Raftery D.

Anal Chem. 2013 Sep 17;85(18):8715-21. doi: 10.1021/ac401712a. Epub 2013 Aug 26.

6.

18O-assisted dynamic metabolomics for individualized diagnostics and treatment of human diseases.

Nemutlu E, Zhang S, Juranic NO, Terzic A, Macura S, Dzeja P.

Croat Med J. 2012 Dec;53(6):529-34. Review.

7.

Applications of NMR spectroscopy to systems biochemistry.

Fan TW, Lane AN.

Prog Nucl Magn Reson Spectrosc. 2016 Feb;92-93:18-53. doi: 10.1016/j.pnmrs.2016.01.005. Epub 2016 Feb 6. Review.

PMID:
26952191
8.

Advances in metabolic profiling.

Barrett D.

Bioanalysis. 2012 Mar;4(6):643-4. doi: 10.4155/bio.12.23.

PMID:
22452253
9.

Clinical applications of metabolomics in oncology: a review.

Spratlin JL, Serkova NJ, Eckhardt SG.

Clin Cancer Res. 2009 Jan 15;15(2):431-40. doi: 10.1158/1078-0432.CCR-08-1059. Review.

10.

Stable isotope-resolved metabolomics (SIRM) in cancer research with clinical application to nonsmall cell lung cancer.

Lane AN, Fan TW, Bousamra M 2nd, Higashi RM, Yan J, Miller DM.

OMICS. 2011 Mar;15(3):173-82. doi: 10.1089/omi.2010.0088. Epub 2011 Feb 17. Review.

11.
12.

Nontargeted elucidation of metabolic pathways using stable-isotope tracers and mass spectrometry.

Hiller K, Metallo CM, Kelleher JK, Stephanopoulos G.

Anal Chem. 2010 Aug 1;82(15):6621-8. doi: 10.1021/ac1011574.

PMID:
20608743
13.

Overview of mass spectrometry-based metabolomics: opportunities and challenges.

Gowda GA, Djukovic D.

Methods Mol Biol. 2014;1198:3-12. doi: 10.1007/978-1-4939-1258-2_1. Review.

14.

Tracer-based metabolomics: concepts and practices.

Paul Lee WN, Wahjudi PN, Xu J, Go VL.

Clin Biochem. 2010 Nov;43(16-17):1269-77. doi: 10.1016/j.clinbiochem.2010.07.027. Epub 2010 Aug 14. Review.

15.

Systematic NMR analysis of stable isotope labeled metabolite mixtures in plant and animal systems: coarse grained views of metabolic pathways.

Chikayama E, Suto M, Nishihara T, Shinozaki K, Kikuchi J.

PLoS One. 2008;3(11):e3805. doi: 10.1371/journal.pone.0003805. Epub 2008 Nov 25. Erratum in: PLoS One. 2009;4(4). doi: 10.1371/annotation/b9b4135b-d76f-4990-b5e4-a70d85acf8e6. Hirayama, Takashi [removed]. PLoS One. 2009;4(4). doi: 10.1371/annotation/55efe5d9-ca11-4f68-ac03-49a31d803161.

16.

Metabolomics and fluxomics approaches.

Cascante M, Marin S.

Essays Biochem. 2008;45:67-81. doi: 10.1042/BSE0450067. Review.

PMID:
18793124
17.

NMR-based stable isotope resolved metabolomics in systems biochemistry.

Fan TW, Lane AN.

J Biomol NMR. 2011 Apr;49(3-4):267-80. doi: 10.1007/s10858-011-9484-6. Epub 2011 Feb 26. Erratum in: J Biomol NMR. 2011 Apr;49(3-4):325.

18.

Metabolomics-based methods for early disease diagnostics.

Gowda GA, Zhang S, Gu H, Asiago V, Shanaiah N, Raftery D.

Expert Rev Mol Diagn. 2008 Sep;8(5):617-33. doi: 10.1586/14737159.8.5.617. Review.

19.

Liquid-liquid extraction combined with differential isotope dimethylaminophenacyl labeling for improved metabolomic profiling of organic acids.

Peng J, Li L.

Anal Chim Acta. 2013 Nov 25;803:97-105. doi: 10.1016/j.aca.2013.07.045. Epub 2013 Jul 27.

PMID:
24216202
20.

Isotopomer-based metabolomic analysis by NMR and mass spectrometry.

Lane AN, Fan TW, Higashi RM.

Methods Cell Biol. 2008;84:541-88.

PMID:
17964943
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