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MicroRNAs and their isomiRs function cooperatively to target common biological pathways.

Cloonan N, Wani S, Xu Q, Gu J, Lea K, Heater S, Barbacioru C, Steptoe AL, Martin HC, Nourbakhsh E, Krishnan K, Gardiner B, Wang X, Nones K, Steen JA, Matigian NA, Wood DL, Kassahn KS, Waddell N, Shepherd J, Lee C, Ichikawa J, McKernan K, Bramlett K, Kuersten S, Grimmond SM.

Genome Biol. 2011 Dec 30;12(12):R126. doi: 10.1186/gb-2011-12-12-r126.


Beta cell 5'-shifted isomiRs are candidate regulatory hubs in type 2 diabetes.

Baran-Gale J, Fannin EE, Kurtz CL, Sethupathy P.

PLoS One. 2013 Sep 9;8(9):e73240. doi: 10.1371/journal.pone.0073240. eCollection 2013.


Methods for validation of miRNA sequence variants and the cleavage of their targets.

Jeong DH, Green PJ.

Methods. 2012 Oct;58(2):135-43. doi: 10.1016/j.ymeth.2012.08.005. Epub 2012 Aug 17.


Deep sequencing of small RNAs identifies canonical and non-canonical miRNA and endogenous siRNAs in mammalian somatic tissues.

Castellano L, Stebbing J.

Nucleic Acids Res. 2013 Mar 1;41(5):3339-51. doi: 10.1093/nar/gks1474. Epub 2013 Jan 15.


Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types.

Guduric-Fuchs J, O'Connor A, Camp B, O'Neill CL, Medina RJ, Simpson DA.

BMC Genomics. 2012 Aug 1;13:357. doi: 10.1186/1471-2164-13-357.


A highly expressed miR-101 isomiR is a functional silencing small RNA.

Llorens F, Bañez-Coronel M, Pantano L, del Río JA, Ferrer I, Estivill X, Martí E.

BMC Genomics. 2013 Feb 15;14:104. doi: 10.1186/1471-2164-14-104.


A comprehensive survey of miRNA repertoire and 3' addition events in the placentas of patients with pre-eclampsia from high-throughput sequencing.

Guo L, Yang Q, Lu J, Li H, Ge Q, Gu W, Bai Y, Lu Z.

PLoS One. 2011;6(6):e21072. doi: 10.1371/journal.pone.0021072. Epub 2011 Jun 22.


Distinctive profile of IsomiR expression and novel microRNAs in rat heart left ventricle.

McGahon MK, Yarham JM, Daly A, Guduric-Fuchs J, Ferguson LJ, Simpson DA, Collins A.

PLoS One. 2013 Jun 14;8(6):e65809. doi: 10.1371/journal.pone.0065809. Print 2013.


Discovery of microRNA regulatory networks by integrating multidimensional high-throughput data.

Yang JH, Qu LH.

Adv Exp Med Biol. 2013;774:251-66. doi: 10.1007/978-94-007-5590-1_13.


Genome-wide identification of targets and function of individual MicroRNAs in mouse embryonic stem cells.

Hanina SA, Mifsud W, Down TA, Hayashi K, O'Carroll D, Lao K, Miska EA, Surani MA.

PLoS Genet. 2010 Oct 21;6(10):e1001163. doi: 10.1371/journal.pgen.1001163.


Analysis of the microRNA transcriptome and expression of different isomiRs in human peripheral blood mononuclear cells.

Vaz C, Ahmad HM, Bharti R, Pandey P, Kumar L, Kulshreshtha R, Bhattacharya A.

BMC Res Notes. 2013 Sep 28;6:390. doi: 10.1186/1756-0500-6-390.


Transfection of siRNAs can alter miRNA levels and trigger non-specific protein degradation in mammalian cells.

Liang XH, Hart CE, Crooke ST.

Biochim Biophys Acta. 2013 May;1829(5):455-68. doi: 10.1016/j.bbagrm.2013.01.011. Epub 2013 Feb 8.


Close association between paralogous multiple isomiRs and paralogous/orthologues miRNA sequences implicates dominant sequence selection across various animal species.

Guo L, Zhao Y, Zhang H, Yang S, Chen F.

Gene. 2013 Sep 25;527(2):624-9. doi: 10.1016/j.gene.2013.06.083. Epub 2013 Jul 13.


A least angle regression model for the prediction of canonical and non-canonical miRNA-mRNA interactions.

Engelmann JC, Spang R.

PLoS One. 2012;7(7):e40634. doi: 10.1371/journal.pone.0040634. Epub 2012 Jul 17.


Widespread regulation of miRNA biogenesis at the Dicer step by the cold-inducible RNA-binding protein, RBM3.

Pilotte J, Dupont-Versteegden EE, Vanderklish PW.

PLoS One. 2011;6(12):e28446. doi: 10.1371/journal.pone.0028446. Epub 2011 Dec 1.


Concordant and discordant regulation of target genes by miR-31 and its isoforms.

Chan YT, Lin YC, Lin RJ, Kuo HH, Thang WC, Chiu KP, Yu AL.

PLoS One. 2013;8(3):e58169. doi: 10.1371/journal.pone.0058169. Epub 2013 Mar 5.


Microarray and deep sequencing cross-platform analysis of the mirRNome and isomiR variation in response to epidermal growth factor.

Llorens F, Hummel M, Pantano L, Pastor X, Vivancos A, Castillo E, Mattlin H, Ferrer A, Ingham M, Noguera M, Kofler R, Dohm JC, Pluvinet R, Bayés M, Himmelbauer H, del Rio JA, Martí E, Sumoy L.

BMC Genomics. 2013 Jun 1;14:371. doi: 10.1186/1471-2164-14-371.


Deep-sequencing of human Argonaute-associated small RNAs provides insight into miRNA sorting and reveals Argonaute association with RNA fragments of diverse origin.

Burroughs AM, Ando Y, de Hoon MJ, Tomaru Y, Suzuki H, Hayashizaki Y, Daub CO.

RNA Biol. 2011 Jan-Feb;8(1):158-77. Epub 2011 Jan 1.


Differential expression patterns of conserved miRNAs and isomiRs during Atlantic halibut development.

Bizuayehu TT, Lanes CF, Furmanek T, Karlsen BO, Fernandes JM, Johansen SD, Babiak I.

BMC Genomics. 2012 Jan 10;13:11. doi: 10.1186/1471-2164-13-11.


Global expression analysis of miRNA gene cluster and family based on isomiRs from deep sequencing data.

Guo L, Lu Z.

Comput Biol Chem. 2010 Jun;34(3):165-71. doi: 10.1016/j.compbiolchem.2010.06.001. Epub 2010 Jun 18.

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