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Items: 1 to 20 of 313

1.

Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway.

Tarassishin L, Suh HS, Lee SC.

J Neuroinflammation. 2011 Dec 30;8:187. doi: 10.1186/1742-2094-8-187.

2.

Interferon regulatory factor 3 inhibits astrocyte inflammatory gene expression through suppression of the proinflammatory miR-155 and miR-155*.

Tarassishin L, Loudig O, Bauman A, Shafit-Zagardo B, Suh HS, Lee SC.

Glia. 2011 Dec;59(12):1911-22. doi: 10.1002/glia.21233.

3.

Phosphatidylinositol 3-kinase activation attenuates the TLR2-mediated macrophage proinflammatory cytokine response to Francisella tularensis live vaccine strain.

Medina EA, Morris IR, Berton MT.

J Immunol. 2010 Dec 15;185(12):7562-72. doi: 10.4049/jimmunol.0903790. Epub 2010 Nov 22.

4.

Increased interleukin-17 production via a phosphoinositide 3-kinase/Akt and nuclear factor kappaB-dependent pathway in patients with rheumatoid arthritis.

Kim KW, Cho ML, Park MK, Yoon CH, Park SH, Lee SH, Kim HY.

Arthritis Res Ther. 2005;7(1):R139-48. Epub 2004 Nov 29.

5.

Phosphatidylinositol-3-kinase and Akt are required for RIG-I-mediated anti-viral signalling through cross-talk with IPS-1.

Yeon SH, Song MJ, Kang HR, Lee JY.

Immunology. 2015 Feb;144(2):312-20. doi: 10.1111/imm.12373.

6.

TLR3 and TLR4 are innate antiviral immune receptors in human microglia: role of IRF3 in modulating antiviral and inflammatory response in the CNS.

Suh HS, Zhao ML, Choi N, Belbin TJ, Brosnan CF, Lee SC.

Virology. 2009 Sep 30;392(2):246-59. doi: 10.1016/j.virol.2009.07.001. Epub 2009 Jul 30.

7.

Interferon regulatory factor 3 alters glioma inflammatory and invasive properties.

Tarassishin L, Lee SC.

J Neurooncol. 2013 Jun;113(2):185-94. doi: 10.1007/s11060-013-1109-3. Epub 2013 Mar 20.

PMID:
23512614
8.
9.

LPS preconditioning redirects TLR signaling following stroke: TRIF-IRF3 plays a seminal role in mediating tolerance to ischemic injury.

Vartanian KB, Stevens SL, Marsh BJ, Williams-Karnesky R, Lessov NS, Stenzel-Poore MP.

J Neuroinflammation. 2011 Oct 14;8:140. doi: 10.1186/1742-2094-8-140.

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12.

Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12).

Suh HS, Choi N, Tarassishin L, Lee SC.

PLoS One. 2012;7(4):e35115. doi: 10.1371/journal.pone.0035115. Epub 2012 Apr 11.

14.

Morphine mediates a proinflammatory phenotype via μ-opioid receptor-PKCɛ-Akt-ERK1/2 signaling pathway in activated microglial cells.

Merighi S, Gessi S, Varani K, Fazzi D, Stefanelli A, Borea PA.

Biochem Pharmacol. 2013 Aug 15;86(4):487-96. doi: 10.1016/j.bcp.2013.05.027. Epub 2013 Jun 21.

PMID:
23796752
15.

LY294002 inhibits interferon-gamma-stimulated inducible nitric oxide synthase expression in BV2 microglial cells.

Hwang SY, Jung JS, Lim SJ, Kim JY, Kim TH, Cho KH, Han IO.

Biochem Biophys Res Commun. 2004 Jun 4;318(3):691-7.

PMID:
15144893
17.

Astrocyte indoleamine 2,3-dioxygenase is induced by the TLR3 ligand poly(I:C): mechanism of induction and role in antiviral response.

Suh HS, Zhao ML, Rivieccio M, Choi S, Connolly E, Zhao Y, Takikawa O, Brosnan CF, Lee SC.

J Virol. 2007 Sep;81(18):9838-50. Epub 2007 Jul 11.

18.

Differential involvement of phosphoinositide 3-kinase/Akt in human RPE MCP-1 and IL-8 expression.

Bian ZM, Elner SG, Yoshida A, Elner VM.

Invest Ophthalmol Vis Sci. 2004 Jun;45(6):1887-96.

PMID:
15161854
19.

Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharide.

Martin M, Schifferle RE, Cuesta N, Vogel SN, Katz J, Michalek SM.

J Immunol. 2003 Jul 15;171(2):717-25.

20.

Peptidoglycan enhances proinflammatory cytokine expression through the TLR2 receptor, MyD88, phosphatidylinositol 3-kinase/AKT and NF-kappaB pathways in BV-2 microglia.

Lin HY, Tang CH, Chen YH, Wei IH, Chen JH, Lai CH, Lu DY.

Int Immunopharmacol. 2010 Aug;10(8):883-91. doi: 10.1016/j.intimp.2010.04.026. Epub 2010 May 5.

PMID:
20451669
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