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Complete genome sequences of three Pseudomonas aeruginosa isolates with phenotypes of polymyxin B adaptation and inducible resistance.

Boyle B, Fernandez L, Laroche J, Kukavica-Ibrulj I, Mendes CM, Hancock RW, Levesque RC.

J Bacteriol. 2012 Jan;194(2):529-30. doi: 10.1128/JB.06246-11.


Involvement of pmrAB and phoPQ in polymyxin B adaptation and inducible resistance in non-cystic fibrosis clinical isolates of Pseudomonas aeruginosa.

Schurek KN, Sampaio JL, Kiffer CR, Sinto S, Mendes CM, Hancock RE.

Antimicrob Agents Chemother. 2009 Oct;53(10):4345-51. doi: 10.1128/AAC.01267-08. Epub 2009 Jul 27.


A single amino acid substitution in PmrB is associated with polymyxin B resistance in clinical isolate of Pseudomonas aeruginosa.

Abraham N, Kwon DH.

FEMS Microbiol Lett. 2009 Sep;298(2):249-54. doi: 10.1111/j.1574-6968.2009.01720.x. Epub 2009 Jul 10.


Comparison of disc diffusion, Etest and broth microdilution for testing susceptibility of carbapenem-resistant P. aeruginosa to polymyxins.

van der Heijden IM, Levin AS, De Pedri EH, Fung L, Rossi F, Duboc G, Barone AA, Costa SF.

Ann Clin Microbiol Antimicrob. 2007 Aug 15;6:8.


Alterations in two-component regulatory systems of phoPQ and pmrAB are associated with polymyxin B resistance in clinical isolates of Pseudomonas aeruginosa.

Barrow K, Kwon DH.

Antimicrob Agents Chemother. 2009 Dec;53(12):5150-4. doi: 10.1128/AAC.00893-09. Epub 2009 Sep 14.


Adaptive resistance to the "last hope" antibiotics polymyxin B and colistin in Pseudomonas aeruginosa is mediated by the novel two-component regulatory system ParR-ParS.

Fernández L, Gooderham WJ, Bains M, McPhee JB, Wiegand I, Hancock RE.

Antimicrob Agents Chemother. 2010 Aug;54(8):3372-82. doi: 10.1128/AAC.00242-10. Epub 2010 Jun 14.


Citywide emergence of Pseudomonas aeruginosa strains with reduced susceptibility to polymyxin B.

Landman D, Bratu S, Alam M, Quale J.

J Antimicrob Chemother. 2005 Jun;55(6):954-7. Epub 2005 May 9.


Characterization of the polymyxin B resistome of Pseudomonas aeruginosa.

Fernández L, Alvarez-Ortega C, Wiegand I, Olivares J, Kocíncová D, Lam JS, Martínez JL, Hancock RE.

Antimicrob Agents Chemother. 2013 Jan;57(1):110-9. doi: 10.1128/AAC.01583-12. Epub 2012 Oct 15.


Emergence of polymyxin B resistance influences pathogenicity in Pseudomonas aeruginosa mutators.

Bulman ZP, Sutton MD, Ly NS, Bulitta JB, Holden PN, Nation RL, Li J, Tsuji BT.

Antimicrob Agents Chemother. 2015 Jul;59(7):4343-6. doi: 10.1128/AAC.04629-14. Epub 2015 Apr 27.


Multidrug-resistant Pseudomonas aeruginosa in Brooklyn, New York: molecular epidemiology and in vitro activity of polymyxin B.

Bratu S, Quale J, Cebular S, Heddurshetti R, Landman D.

Eur J Clin Microbiol Infect Dis. 2005 Mar;24(3):196-201.


In vitro and in vivo potency of polymyxin B against IMP-type metallo-beta-lactamase-producing Pseudomonas aeruginosa.

Miyajima Y, Hiramatsu K, Mizukami E, Morinaga R, Ishii H, Shirai R, Kishi K, Tokimatsu I, Saikawa T, Kadota J.

Int J Antimicrob Agents. 2008 Nov;32(5):437-40. doi: 10.1016/j.ijantimicag.2008.05.006. Epub 2008 Aug 19.


Cation concentration variability of four distinct Mueller-Hinton agar brands influences polymyxin B susceptibility results.

Girardello R, Bispo PJ, Yamanaka TM, Gales AC.

J Clin Microbiol. 2012 Jul;50(7):2414-8. doi: 10.1128/JCM.06686-11. Epub 2012 May 2.


PmrB mutations promote polymyxin resistance of Pseudomonas aeruginosa isolated from colistin-treated cystic fibrosis patients.

Moskowitz SM, Brannon MK, Dasgupta N, Pier M, Sgambati N, Miller AK, Selgrade SE, Miller SI, Denton M, Conway SP, Johansen HK, Høiby N.

Antimicrob Agents Chemother. 2012 Feb;56(2):1019-30. doi: 10.1128/AAC.05829-11. Epub 2011 Nov 21.


The two-component system CprRS senses cationic peptides and triggers adaptive resistance in Pseudomonas aeruginosa independently of ParRS.

Fernández L, Jenssen H, Bains M, Wiegand I, Gooderham WJ, Hancock RE.

Antimicrob Agents Chemother. 2012 Dec;56(12):6212-22. doi: 10.1128/AAC.01530-12. Epub 2012 Sep 24.


Contemporary antimicrobial activity of triple antibiotic ointment: a multiphased study of recent clinical isolates in the United States and Australia.

Jones RN, Li Q, Kohut B, Biedenbach DJ, Bell J, Turnidge JD.

Diagn Microbiol Infect Dis. 2006 Jan;54(1):63-71.


Involvement of outer membrane of Pseudomonas cepacia in aminoglycoside and polymyxin resistance.

Moore RA, Hancock RE.

Antimicrob Agents Chemother. 1986 Dec;30(6):923-6.

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