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Items: 1 to 20 of 262

1.

Caffeic acid phenethyl ester extends survival of a mouse model of amyotrophic lateral sclerosis.

Fontanilla CV, Wei X, Zhao L, Johnstone B, Pascuzzi RM, Farlow MR, Du Y.

Neuroscience. 2012 Mar 15;205:185-93. doi: 10.1016/j.neuroscience.2011.12.025. Epub 2011 Dec 24.

PMID:
22206942
2.

Overexpression of Abeta is associated with acceleration of onset of motor impairment and superoxide dismutase 1 aggregation in an amyotrophic lateral sclerosis mouse model.

Li QX, Mok SS, Laughton KM, McLean CA, Volitakis I, Cherny RA, Cheung NS, White AR, Masters CL.

Aging Cell. 2006 Apr;5(2):153-65.

3.

Celastrol blocks neuronal cell death and extends life in transgenic mouse model of amyotrophic lateral sclerosis.

Kiaei M, Kipiani K, Petri S, Chen J, Calingasan NY, Beal MF.

Neurodegener Dis. 2005;2(5):246-54.

PMID:
16909005
4.

Inhibition of p38 mitogen activated protein kinase activation and mutant SOD1(G93A)-induced motor neuron death.

Dewil M, dela Cruz VF, Van Den Bosch L, Robberecht W.

Neurobiol Dis. 2007 May;26(2):332-41. Epub 2007 Feb 6.

PMID:
17346981
5.

Effects of the PPARgamma activator pioglitazone on p38 MAP kinase and IkappaBalpha in the spinal cord of a transgenic mouse model of amyotrophic lateral sclerosis.

Shibata N, Kawaguchi-Niida M, Yamamoto T, Toi S, Hirano A, Kobayashi M.

Neuropathology. 2008 Aug;28(4):387-98. doi: 10.1111/j.1440-1789.2008.00890.x. Epub 2008 Feb 26.

PMID:
18312546
6.

Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis.

Kriz J, Nguyen MD, Julien JP.

Neurobiol Dis. 2002 Aug;10(3):268-78.

PMID:
12270689
7.

Guanabenz delays the onset of disease symptoms, extends lifespan, improves motor performance and attenuates motor neuron loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis.

Jiang HQ, Ren M, Jiang HZ, Wang J, Zhang J, Yin X, Wang SY, Qi Y, Wang XD, Feng HL.

Neuroscience. 2014 Sep 26;277:132-8. doi: 10.1016/j.neuroscience.2014.03.047. Epub 2014 Mar 31.

PMID:
24699224
8.

Autophagy activation and neuroprotection by progesterone in the G93A-SOD1 transgenic mouse model of amyotrophic lateral sclerosis.

Kim J, Kim TY, Cho KS, Kim HN, Koh JY.

Neurobiol Dis. 2013 Nov;59:80-5. doi: 10.1016/j.nbd.2013.07.011. Epub 2013 Jul 26.

PMID:
23891729
9.

Peroxisome proliferator-activated receptor-gamma agonist extends survival in transgenic mouse model of amyotrophic lateral sclerosis.

Kiaei M, Kipiani K, Chen J, Calingasan NY, Beal MF.

Exp Neurol. 2005 Feb;191(2):331-6.

PMID:
15649489
10.

Fasudil, a rho kinase inhibitor, limits motor neuron loss in experimental models of amyotrophic lateral sclerosis.

Takata M, Tanaka H, Kimura M, Nagahara Y, Tanaka K, Kawasaki K, Seto M, Tsuruma K, Shimazawa M, Hara H.

Br J Pharmacol. 2013 Sep;170(2):341-51. doi: 10.1111/bph.12277.

11.

The CB2 cannabinoid agonist AM-1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onset.

Shoemaker JL, Seely KA, Reed RL, Crow JP, Prather PL.

J Neurochem. 2007 Apr;101(1):87-98. Epub 2007 Jan 4.

12.

DL-3-n-butylphthalide extends survival by attenuating glial activation in a mouse model of amyotrophic lateral sclerosis.

Feng X, Peng Y, Liu M, Cui L.

Neuropharmacology. 2012 Feb;62(2):1004-10. doi: 10.1016/j.neuropharm.2011.10.009. Epub 2011 Nov 2.

PMID:
22056419
13.

Bromocriptine methylate suppresses glial inflammation and moderates disease progression in a mouse model of amyotrophic lateral sclerosis.

Tanaka K, Kanno T, Yanagisawa Y, Yasutake K, Hadano S, Yoshii F, Ikeda JE.

Exp Neurol. 2011 Nov;232(1):41-52. doi: 10.1016/j.expneurol.2011.08.001. Epub 2011 Aug 16.

PMID:
21867702
14.

Caffeic acid phenethyl ester prevents apoptotic cell death in the developing rat brain after pentylenetetrazole-induced status epilepticus.

Yiş U, Topçu Y, Özbal S, Tuğyan K, Bayram E, Karakaya P, Yilmaz O, Kurul SH.

Epilepsy Behav. 2013 Nov;29(2):275-80. doi: 10.1016/j.yebeh.2013.08.002. Epub 2013 Sep 6.

PMID:
24012504
15.

Activation of the stress-activated MAP kinase, p38, but not JNK in cortical motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in transgenic mice.

Holasek SS, Wengenack TM, Kandimalla KK, Montano C, Gregor DM, Curran GL, Poduslo JF.

Brain Res. 2005 May 31;1045(1-2):185-98. Epub 2005 Apr 25.

PMID:
15910777
16.

Caffeic acid phenethyl ester protects mice from lethal endotoxin shock and inhibits lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW 264.7 macrophages via the p38/ERK and NF-kappaB pathways.

Jung WK, Choi I, Lee DY, Yea SS, Choi YH, Kim MM, Park SG, Seo SK, Lee SW, Lee CM, Park YM, Choi IW.

Int J Biochem Cell Biol. 2008;40(11):2572-82. doi: 10.1016/j.biocel.2008.05.005. Epub 2008 May 15.

PMID:
18571461
17.

Granulocyte colony stimulating factor attenuates inflammation in a mouse model of amyotrophic lateral sclerosis.

Pollari E, Savchenko E, Jaronen M, Kanninen K, Malm T, Wojciechowski S, Ahtoniemi T, Goldsteins G, Giniatullina R, Giniatullin R, Koistinaho J, Magga J.

J Neuroinflammation. 2011 Jun 28;8:74. doi: 10.1186/1742-2094-8-74.

18.

Death receptor 6 (DR6) antagonist antibody is neuroprotective in the mouse SOD1G93A model of amyotrophic lateral sclerosis.

Huang G, Lee X, Bian Y, Shao Z, Sheng G, Pepinsky RB, Mi S.

Cell Death Dis. 2013 Oct 10;4:e841. doi: 10.1038/cddis.2013.378.

19.

Therapeutic effects of dl-3-n-butylphthalide in a transgenic mouse model of amyotrophic lateral sclerosis.

Feng XH, Yuan W, Peng Y, Liu MS, Cui LY.

Chin Med J (Engl). 2012 May;125(10):1760-6.

20.

Pyruvate slows disease progression in a G93A SOD1 mutant transgenic mouse model.

Park JH, Hong YH, Kim HJ, Kim SM, Kim MJ, Park KS, Sung JJ, Lee KW.

Neurosci Lett. 2007 Feb 21;413(3):265-9. Epub 2006 Dec 13.

PMID:
17174029
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