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Results: 1 to 20 of 91

1.

Ifih1 gene dose effect reveals MDA5-mediated chronic type I IFN gene signature, viral resistance, and accelerated autoimmunity.

Crampton SP, Deane JA, Feigenbaum L, Bolland S.

J Immunol. 2012 Feb 1;188(3):1451-9. doi: 10.4049/jimmunol.1102705. Epub 2011 Dec 28.

PMID:
22205024
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Autoimmune disorders associated with gain of function of the intracellular sensor MDA5.

Funabiki M, Kato H, Miyachi Y, Toki H, Motegi H, Inoue M, Minowa O, Yoshida A, Deguchi K, Sato H, Ito S, Shiroishi T, Takeyasu K, Noda T, Fujita T.

Immunity. 2014 Feb 20;40(2):199-212. doi: 10.1016/j.immuni.2013.12.014. Epub 2014 Feb 13.

PMID:
24530055
[PubMed - indexed for MEDLINE]
3.

Both RIG-I and MDA5 RNA helicases contribute to the induction of alpha/beta interferon in measles virus-infected human cells.

Ikegame S, Takeda M, Ohno S, Nakatsu Y, Nakanishi Y, Yanagi Y.

J Virol. 2010 Jan;84(1):372-9. doi: 10.1128/JVI.01690-09. Epub .

PMID:
19846522
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Interferon induced with helicase C domain 1 (IFIH1) and virus-induced autoimmunity: a review.

Chistiakov DA.

Viral Immunol. 2010 Feb;23(1):3-15. doi: 10.1089/vim.2009.0071. Review.

PMID:
20121398
[PubMed - indexed for MEDLINE]
5.

RNA sensor-induced type I IFN prevents diabetes caused by a ╬▓ cell-tropic virus in mice.

McCartney SA, Vermi W, Lonardi S, Rossini C, Otero K, Calderon B, Gilfillan S, Diamond MS, Unanue ER, Colonna M.

J Clin Invest. 2011 Apr;121(4):1497-507. doi: 10.1172/JCI44005. Epub 2011 Mar 14.

PMID:
21403398
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo.

Gitlin L, Benoit L, Song C, Cella M, Gilfillan S, Holtzman MJ, Colonna M.

PLoS Pathog. 2010 Jan 22;6(1):e1000734. doi: 10.1371/journal.ppat.1000734.

PMID:
20107606
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

TLR7/9 versus TLR3/MDA5 signaling during virus infections and diabetes.

Swiecki M, McCartney SA, Wang Y, Colonna M.

J Leukoc Biol. 2011 Oct;90(4):691-701. doi: 10.1189/jlb.0311166. Epub 2011 Aug 15. Review.

PMID:
21844166
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Regulation of antiviral innate immune responses by RIG-I family of RNA helicases.

Onomoto K, Yoneyama M, Fujita T.

Curr Top Microbiol Immunol. 2007;316:193-205. Review.

PMID:
17969449
[PubMed - indexed for MEDLINE]
9.

Regulation of RLR-mediated innate immune signaling--it is all about keeping the balance.

Eisen├Ącher K, Krug A.

Eur J Cell Biol. 2012 Jan;91(1):36-47. doi: 10.1016/j.ejcb.2011.01.011. Epub 2011 Apr 9. Review.

PMID:
21481967
[PubMed - indexed for MEDLINE]
10.

Melanoma differentiation-associated gene 5 regulates the expression of a chemokine CXCL10 in human mesangial cells: implications for chronic inflammatory renal diseases.

Imaizumi T, Aizawa-Yashiro T, Tsuruga K, Tanaka H, Matsumiya T, Yoshida H, Tatsuta T, Xing F, Hayakari R, Satoh K.

Tohoku J Exp Med. 2012;228(1):17-26.

PMID:
22892369
[PubMed - indexed for MEDLINE]
Free Article
11.

Negative regulation of MDA5- but not RIG-I-mediated innate antiviral signaling by the dihydroxyacetone kinase.

Diao F, Li S, Tian Y, Zhang M, Xu LG, Zhang Y, Wang RP, Chen D, Zhai Z, Zhong B, Tien P, Shu HB.

Proc Natl Acad Sci U S A. 2007 Jul 10;104(28):11706-11. Epub 2007 Jun 28.

PMID:
17600090
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Melanoma differentiation-associated gene 5 is critical for protection against Theiler's virus-induced demyelinating disease.

Jin YH, Kim SJ, So EY, Meng L, Colonna M, Kim BS.

J Virol. 2012 Feb;86(3):1531-43. doi: 10.1128/JVI.06457-11. Epub 2011 Nov 16.

PMID:
22090123
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Retinoic acid inducible gene-I and melanoma differentiation-associated gene 5 are induced but not essential for dengue virus induced type I interferon response.

Qin CF, Zhao H, Liu ZY, Jiang T, Deng YQ, Yu XD, Yu M, Qin ED.

Mol Biol Rep. 2011 Aug;38(6):3867-73. doi: 10.1007/s11033-010-0502-7. Epub 2010 Nov 27.

PMID:
21113677
[PubMed - indexed for MEDLINE]
14.

Establishment and maintenance of the innate antiviral response to West Nile Virus involves both RIG-I and MDA5 signaling through IPS-1.

Fredericksen BL, Keller BC, Fornek J, Katze MG, Gale M Jr.

J Virol. 2008 Jan;82(2):609-16. Epub 2007 Oct 31.

PMID:
17977974
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity.

Negishi H, Osawa T, Ogami K, Ouyang X, Sakaguchi S, Koshiba R, Yanai H, Seko Y, Shitara H, Bishop K, Yonekawa H, Tamura T, Kaisho T, Taya C, Taniguchi T, Honda K.

Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20446-51. doi: 10.1073/pnas.0810372105. Epub 2008 Dec 11.

PMID:
19074283
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Constitutive antiviral immunity at the expense of autoimmunity.

Todd JA.

Immunity. 2014 Feb 20;40(2):167-9. doi: 10.1016/j.immuni.2014.01.009.

PMID:
24560191
[PubMed - indexed for MEDLINE]
17.

LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses.

Satoh T, Kato H, Kumagai Y, Yoneyama M, Sato S, Matsushita K, Tsujimura T, Fujita T, Akira S, Takeuchi O.

Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1512-7. doi: 10.1073/pnas.0912986107. Epub 2010 Jan 8.

PMID:
20080593
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A selective contribution of the RIG-I-like receptor pathway to type I interferon responses activated by cytosolic DNA.

Choi MK, Wang Z, Ban T, Yanai H, Lu Y, Koshiba R, Nakaima Y, Hangai S, Savitsky D, Nakasato M, Negishi H, Takeuchi O, Honda K, Akira S, Tamura T, Taniguchi T.

Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17870-5. doi: 10.1073/pnas.0909545106. Epub 2009 Oct 1.

PMID:
19805092
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

RIG-I/MDA5/MAVS are required to signal a protective IFN response in rotavirus-infected intestinal epithelium.

Broquet AH, Hirata Y, McAllister CS, Kagnoff MF.

J Immunol. 2011 Feb 1;186(3):1618-26. doi: 10.4049/jimmunol.1002862. Epub 2010 Dec 27.

PMID:
21187438
[PubMed - indexed for MEDLINE]
Free Article
20.

Loss of DExD/H box RNA helicase LGP2 manifests disparate antiviral responses.

Venkataraman T, Valdes M, Elsby R, Kakuta S, Caceres G, Saijo S, Iwakura Y, Barber GN.

J Immunol. 2007 May 15;178(10):6444-55.

PMID:
17475874
[PubMed - indexed for MEDLINE]
Free Article

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