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Results: 1 to 20 of 231

1.

Biological and clinical heterogeneity of MYCN-amplified medulloblastoma.

Korshunov A, Remke M, Kool M, Hielscher T, Northcott PA, Williamson D, Pfaff E, Witt H, Jones DT, Ryzhova M, Cho YJ, Wittmann A, Benner A, Weiss WA, von Deimling A, Scheurlen W, Kulozik AE, Clifford SC, Peter Collins V, Westermann F, Taylor MD, Lichter P, Pfister SM.

Acta Neuropathol. 2012 Apr;123(4):515-27. doi: 10.1007/s00401-011-0918-8. Epub 2011 Dec 9.

PMID:
22160402
[PubMed - indexed for MEDLINE]
2.

Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification.

Korshunov A, Remke M, Werft W, Benner A, Ryzhova M, Witt H, Sturm D, Wittmann A, Schöttler A, Felsberg J, Reifenberger G, Rutkowski S, Scheurlen W, Kulozik AE, von Deimling A, Lichter P, Pfister SM.

J Clin Oncol. 2010 Jun 20;28(18):3054-60. doi: 10.1200/JCO.2009.25.7121. Epub 2010 May 17.

PMID:
20479417
[PubMed - indexed for MEDLINE]
Free Article
3.

Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci.

Pfister S, Remke M, Benner A, Mendrzyk F, Toedt G, Felsberg J, Wittmann A, Devens F, Gerber NU, Joos S, Kulozik A, Reifenberger G, Rutkowski S, Wiestler OD, Radlwimmer B, Scheurlen W, Lichter P, Korshunov A.

J Clin Oncol. 2009 Apr 1;27(10):1627-36. doi: 10.1200/JCO.2008.17.9432. Epub 2009 Mar 2.

PMID:
19255330
[PubMed - indexed for MEDLINE]
Free Article
4.

MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma.

Ryan SL, Schwalbe EC, Cole M, Lu Y, Lusher ME, Megahed H, O'Toole K, Nicholson SL, Bognar L, Garami M, Hauser P, Korshunov A, Pfister SM, Williamson D, Taylor RE, Ellison DW, Bailey S, Clifford SC.

Acta Neuropathol. 2012 Apr;123(4):501-13. doi: 10.1007/s00401-011-0923-y. Epub 2011 Dec 3.

PMID:
22139329
[PubMed - indexed for MEDLINE]
5.

Prognostic classification of pediatric medulloblastoma based on chromosome 17p loss, expression of MYCC and MYCN, and Wnt pathway activation.

Park AK, Lee SJ, Phi JH, Wang KC, Kim DG, Cho BK, Haberler C, Fattet S, Dufour C, Puget S, Sainte-Rose C, Bourdeaut F, Grill J, Delattre O, Kim SK, Park WY.

Neuro Oncol. 2012 Feb;14(2):203-14. doi: 10.1093/neuonc/nor196. Epub 2011 Nov 16.

PMID:
22090452
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Low-level copy number changes of MYC genes have a prognostic impact in medulloblastoma.

Zitterbart K, Filkova H, Tomasikova L, Necesalova E, Zambo I, Kantorova D, Slamova I, Vranova V, Zezulkova D, Pesakova M, Pavelka Z, Veselska R, Kuglik P, Sterba J.

J Neurooncol. 2011 Mar;102(1):25-33. doi: 10.1007/s11060-010-0289-3. Epub 2010 Jul 8.

PMID:
20607354
[PubMed - indexed for MEDLINE]
7.

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition.

Kool M, Jones DT, Jäger N, Northcott PA, Pugh TJ, Hovestadt V, Piro RM, Esparza LA, Markant SL, Remke M, Milde T, Bourdeaut F, Ryzhova M, Sturm D, Pfaff E, Stark S, Hutter S, Seker-Cin H, Johann P, Bender S, Schmidt C, Rausch T, Shih D, Reimand J, Sieber L, Wittmann A, Linke L, Witt H, Weber UD, Zapatka M, König R, Beroukhim R, Bergthold G, van Sluis P, Volckmann R, Koster J, Versteeg R, Schmidt S, Wolf S, Lawerenz C, Bartholomae CC, von Kalle C, Unterberg A, Herold-Mende C, Hofer S, Kulozik AE, von Deimling A, Scheurlen W, Felsberg J, Reifenberger G, Hasselblatt M, Crawford JR, Grant GA, Jabado N, Perry A, Cowdrey C, Croul S, Zadeh G, Korbel JO, Doz F, Delattre O, Bader GD, McCabe MG, Collins VP, Kieran MW, Cho YJ, Pomeroy SL, Witt O, Brors B, Taylor MD, Schüller U, Korshunov A, Eils R, Wechsler-Reya RJ, Lichter P, Pfister SM; ICGC PedBrain Tumor Project.

Cancer Cell. 2014 Mar 17;25(3):393-405. doi: 10.1016/j.ccr.2014.02.004.

PMID:
24651015
[PubMed - indexed for MEDLINE]
8.

TP53 mutation is frequently associated with CTNNB1 mutation or MYCN amplification and is compatible with long-term survival in medulloblastoma.

Pfaff E, Remke M, Sturm D, Benner A, Witt H, Milde T, von Bueren AO, Wittmann A, Schöttler A, Jorch N, Graf N, Kulozik AE, Witt O, Scheurlen W, von Deimling A, Rutkowski S, Taylor MD, Tabori U, Lichter P, Korshunov A, Pfister SM.

J Clin Oncol. 2010 Dec 10;28(35):5188-96. doi: 10.1200/JCO.2010.31.1670. Epub 2010 Nov 8.

PMID:
21060032
[PubMed - indexed for MEDLINE]
Free Article
9.

Combined histopathological and molecular cytogenetic stratification of medulloblastoma patients.

Lamont JM, McManamy CS, Pearson AD, Clifford SC, Ellison DW.

Clin Cancer Res. 2004 Aug 15;10(16):5482-93.

PMID:
15328187
[PubMed - indexed for MEDLINE]
Free Article
10.

Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct.

Northcott PA, Hielscher T, Dubuc A, Mack S, Shih D, Remke M, Al-Halabi H, Albrecht S, Jabado N, Eberhart CG, Grajkowska W, Weiss WA, Clifford SC, Bouffet E, Rutka JT, Korshunov A, Pfister S, Taylor MD.

Acta Neuropathol. 2011 Aug;122(2):231-40. doi: 10.1007/s00401-011-0846-7. Epub 2011 Jun 17.

PMID:
21681522
[PubMed - indexed for MEDLINE]
11.

Accumulation of genomic aberrations during clinical progression of medulloblastoma.

Korshunov A, Benner A, Remke M, Lichter P, von Deimling A, Pfister S.

Acta Neuropathol. 2008 Oct;116(4):383-90. doi: 10.1007/s00401-008-0422-y. Epub 2008 Aug 15.

PMID:
18704466
[PubMed - indexed for MEDLINE]
12.

Preponderance of sonic hedgehog pathway activation characterizes adult medulloblastoma.

Al-Halabi H, Nantel A, Klekner A, Guiot MC, Albrecht S, Hauser P, Garami M, Bognar L, Kavan P, Gerges N, Shirinian M, Roberge D, Muanza T, Jabado N.

Acta Neuropathol. 2011 Feb;121(2):229-39. doi: 10.1007/s00401-010-0780-0. Epub 2010 Nov 24.

PMID:
21107850
[PubMed - indexed for MEDLINE]
13.

[Characteristics of medulloblastoma in children under age of three years].

Ryzhova MV, Zheludkova OG, Kumirova ÉV, Shishkina LV, Panina TN, Gorelyshev SK, Khukhlaeva EA, Mazerkina NA, Matuev KB, Medvedeva OA, Tarasova EM, Kholodov BV, Kapitul'skaia OIu.

Zh Vopr Neirokhir Im N N Burdenko. 2013;77(1):3-10; discussion 11. Russian.

PMID:
23659115
[PubMed - indexed for MEDLINE]
Free Article
14.

Cytogenetic prognostication within medulloblastoma subgroups.

Shih DJ, Northcott PA, Remke M, Korshunov A, Ramaswamy V, Kool M, Luu B, Yao Y, Wang X, Dubuc AM, Garzia L, Peacock J, Mack SC, Wu X, Rolider A, Morrissy AS, Cavalli FM, Jones DT, Zitterbart K, Faria CC, Schüller U, Kren L, Kumabe T, Tominaga T, Shin Ra Y, Garami M, Hauser P, Chan JA, Robinson S, Bognár L, Klekner A, Saad AG, Liau LM, Albrecht S, Fontebasso A, Cinalli G, De Antonellis P, Zollo M, Cooper MK, Thompson RC, Bailey S, Lindsey JC, Di Rocco C, Massimi L, Michiels EM, Scherer SW, Phillips JJ, Gupta N, Fan X, Muraszko KM, Vibhakar R, Eberhart CG, Fouladi M, Lach B, Jung S, Wechsler-Reya RJ, Fèvre-Montange M, Jouvet A, Jabado N, Pollack IF, Weiss WA, Lee JY, Cho BK, Kim SK, Wang KC, Leonard JR, Rubin JB, de Torres C, Lavarino C, Mora J, Cho YJ, Tabori U, Olson JM, Gajjar A, Packer RJ, Rutkowski S, Pomeroy SL, French PJ, Kloosterhof NK, Kros JM, Van Meir EG, Clifford SC, Bourdeaut F, Delattre O, Doz FF, Hawkins CE, Malkin D, Grajkowska WA, Perek-Polnik M, Bouffet E, Rutka JT, Pfister SM, Taylor MD.

J Clin Oncol. 2014 Mar 20;32(9):886-96. doi: 10.1200/JCO.2013.50.9539. Epub 2014 Feb 3.

PMID:
24493713
[PubMed - indexed for MEDLINE]
15.

Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups.

Ellison DW, Dalton J, Kocak M, Nicholson SL, Fraga C, Neale G, Kenney AM, Brat DJ, Perry A, Yong WH, Taylor RE, Bailey S, Clifford SC, Gilbertson RJ.

Acta Neuropathol. 2011 Mar;121(3):381-96. doi: 10.1007/s00401-011-0800-8. Epub 2011 Jan 26.

PMID:
21267586
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Detection of genetic and chromosomal aberrations in medulloblastomas and primitive neuroectodermal tumors with DNA microarrays.

Kagawa N, Maruno M, Suzuki T, Hashiba T, Hashimoto N, Izumoto S, Yoshimine T.

Brain Tumor Pathol. 2006 Apr;23(1):41-7.

PMID:
18095118
[PubMed - indexed for MEDLINE]
17.

Definition of disease-risk stratification groups in childhood medulloblastoma using combined clinical, pathologic, and molecular variables.

Ellison DW, Kocak M, Dalton J, Megahed H, Lusher ME, Ryan SL, Zhao W, Nicholson SL, Taylor RE, Bailey S, Clifford SC.

J Clin Oncol. 2011 Apr 10;29(11):1400-7. doi: 10.1200/JCO.2010.30.2810. Epub 2010 Oct 4.

PMID:
20921458
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

MicroRNA-182 promotes leptomeningeal spread of non-sonic hedgehog-medulloblastoma.

Bai AH, Milde T, Remke M, Rolli CG, Hielscher T, Cho YJ, Kool M, Northcott PA, Jugold M, Bazhin AV, Eichmüller SB, Kulozik AE, Pscherer A, Benner A, Taylor MD, Pomeroy SL, Kemkemer R, Witt O, Korshunov A, Lichter P, Pfister SM.

Acta Neuropathol. 2012 Apr;123(4):529-38. doi: 10.1007/s00401-011-0924-x. Epub 2011 Dec 2.

PMID:
22134538
[PubMed - indexed for MEDLINE]
19.

Histopathological and molecular prognostic markers in medulloblastoma: c-myc, N-myc, TrkC, and anaplasia.

Eberhart CG, Kratz J, Wang Y, Summers K, Stearns D, Cohen K, Dang CV, Burger PC.

J Neuropathol Exp Neurol. 2004 May;63(5):441-9.

PMID:
15198123
[PubMed - indexed for MEDLINE]
20.

FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma.

Remke M, Hielscher T, Korshunov A, Northcott PA, Bender S, Kool M, Westermann F, Benner A, Cin H, Ryzhova M, Sturm D, Witt H, Haag D, Toedt G, Wittmann A, Schöttler A, von Bueren AO, von Deimling A, Rutkowski S, Scheurlen W, Kulozik AE, Taylor MD, Lichter P, Pfister SM.

J Clin Oncol. 2011 Oct 10;29(29):3852-61. doi: 10.1200/JCO.2011.36.2798. Epub 2011 Sep 12.

PMID:
21911727
[PubMed - indexed for MEDLINE]
Free Article

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