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Results: 1 to 20 of 92

1.

Systems genetics of the nuclear factor-κB signal transduction network. I. Detection of several quantitative trait loci potentially relevant to aging.

Diego VP, Curran JE, Charlesworth J, Peralta JM, Voruganti VS, Cole SA, Dyer TD, Johnson MP, Moses EK, Göring HH, Williams JT, Comuzzie AG, Almasy L, Blangero J, Williams-Blangero S.

Mech Ageing Dev. 2012 Jan;133(1):11-9. doi: 10.1016/j.mad.2011.11.007. Epub 2011 Dec 1.

PMID:
22155176
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling.

Yamamoto M, Sato S, Mori K, Hoshino K, Takeuchi O, Takeda K, Akira S.

J Immunol. 2002 Dec 15;169(12):6668-72.

PMID:
12471095
[PubMed - indexed for MEDLINE]
Free Article
3.

Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta.

Jiang Z, Mak TW, Sen G, Li X.

Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3533-8. Epub 2004 Feb 24.

PMID:
14982987
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Induction of in vitro reprogramming by Toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages: effects of TLR "homotolerance" versus "heterotolerance" on NF-kappa B signaling pathway components.

Dobrovolskaia MA, Medvedev AE, Thomas KE, Cuesta N, Toshchakov V, Ren T, Cody MJ, Michalek SM, Rice NR, Vogel SN.

J Immunol. 2003 Jan 1;170(1):508-19.

PMID:
12496438
[PubMed - indexed for MEDLINE]
Free Article
5.

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.

Fitzgerald KA, Palsson-McDermott EM, Bowie AG, Jefferies CA, Mansell AS, Brady G, Brint E, Dunne A, Gray P, Harte MT, McMurray D, Smith DE, Sims JE, Bird TA, O'Neill LA.

Nature. 2001 Sep 6;413(6851):78-83.

PMID:
11544529
[PubMed - indexed for MEDLINE]
6.

Absence of TRAM restricts Toll-like receptor 4 signaling in vascular endothelial cells to the MyD88 pathway.

Harari OA, Alcaide P, Ahl D, Luscinskas FW, Liao JK.

Circ Res. 2006 May 12;98(9):1134-40. Epub 2006 Mar 30.

PMID:
16574902
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Transcriptional regulation of the human TRIF (TIR domain-containing adaptor protein inducing interferon beta) gene.

Hardy MP, McGGettrick AF, O'Neill LA.

Biochem J. 2004 May 15;380(Pt 1):83-93.

PMID:
14960149
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.

Verstak B, Nagpal K, Bottomley SP, Golenbock DT, Hertzog PJ, Mansell A.

J Biol Chem. 2009 Sep 4;284(36):24192-203. doi: 10.1074/jbc.M109.023044. Epub 2009 Jul 10.

PMID:
19592497
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex.

Youn HS, Lee JY, Fitzgerald KA, Young HA, Akira S, Hwang DH.

J Immunol. 2005 Sep 1;175(5):3339-46.

PMID:
16116226
[PubMed - indexed for MEDLINE]
Free Article
11.

Suppression of MyD88- and TRIF-dependent signaling pathways of Toll-like receptor by (-)-epigallocatechin-3-gallate, a polyphenol component of green tea.

Youn HS, Lee JY, Saitoh SI, Miyake K, Kang KW, Choi YJ, Hwang DH.

Biochem Pharmacol. 2006 Sep 28;72(7):850-9. Epub 2006 Aug 4.

PMID:
16890209
[PubMed - indexed for MEDLINE]
12.

Beta2-adrenergic receptor regulate Toll-like receptor 4-induced late-phase NF-kappaB activation.

Kizaki T, Shirato K, Sakurai T, Ogasawara JE, Oh-ishi S, Matsuoka T, Izawa T, Imaizumi K, Haga S, Ohno H.

Mol Immunol. 2009 Mar;46(6):1195-203. doi: 10.1016/j.molimm.2008.11.005. Epub 2009 Jan 22.

PMID:
19167076
[PubMed - indexed for MEDLINE]
13.

Inhibition of phosphoinositide 3-kinase enhances TRIF-dependent NF-kappa B activation and IFN-beta synthesis downstream of Toll-like receptor 3 and 4.

Aksoy E, Vanden Berghe W, Detienne S, Amraoui Z, Fitzgerald KA, Haegeman G, Goldman M, Willems F.

Eur J Immunol. 2005 Jul;35(7):2200-9.

PMID:
15940673
[PubMed - indexed for MEDLINE]
14.

Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP.

Andreakos E, Sacre SM, Smith C, Lundberg A, Kiriakidis S, Stonehouse T, Monaco C, Feldmann M, Foxwell BM.

Blood. 2004 Mar 15;103(6):2229-37. Epub 2003 Nov 20.

PMID:
14630816
[PubMed - indexed for MEDLINE]
Free Article
15.

Homo-oligomerization is essential for Toll/interleukin-1 receptor domain-containing adaptor molecule-1-mediated NF-kappaB and interferon regulatory factor-3 activation.

Funami K, Sasai M, Oshiumi H, Seya T, Matsumoto M.

J Biol Chem. 2008 Jun 27;283(26):18283-91. doi: 10.1074/jbc.M801013200. Epub 2008 May 1.

PMID:
18450748
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.

Fitzgerald KA, Rowe DC, Barnes BJ, Caffrey DR, Visintin A, Latz E, Monks B, Pitha PM, Golenbock DT.

J Exp Med. 2003 Oct 6;198(7):1043-55. Epub 2003 Sep 29. Erratum in: J Exp Med. 2003 Nov 3;198(9):following 1450.

PMID:
14517278
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Quantitative trait loci for metabolic syndrome in the Hypertension Genetic Epidemiology Network study.

Kraja AT, Hunt SC, Pankow JS, Myers RH, Heiss G, Lewis CE, Rao DC, Province MA.

Obes Res. 2005 Nov;13(11):1885-90.

PMID:
16339118
[PubMed - indexed for MEDLINE]
18.

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway.

Yamamoto M, Sato S, Hemmi H, Hoshino K, Kaisho T, Sanjo H, Takeuchi O, Sugiyama M, Okabe M, Takeda K, Akira S.

Science. 2003 Aug 1;301(5633):640-3. Epub 2003 Jul 10.

PMID:
12855817
[PubMed - indexed for MEDLINE]
Free Article
19.

VP1686, a Vibrio type III secretion protein, induces toll-like receptor-independent apoptosis in macrophage through NF-kappaB inhibition.

Bhattacharjee RN, Park KS, Kumagai Y, Okada K, Yamamoto M, Uematsu S, Matsui K, Kumar H, Kawai T, Iida T, Honda T, Takeuchi O, Akira S.

J Biol Chem. 2006 Dec 1;281(48):36897-904. Epub 2006 Sep 19.

PMID:
16984916
[PubMed - indexed for MEDLINE]
Free Article
20.

The Asp299Gly polymorphism alters TLR4 signaling by interfering with recruitment of MyD88 and TRIF.

Figueroa L, Xiong Y, Song C, Piao W, Vogel SN, Medvedev AE.

J Immunol. 2012 May 1;188(9):4506-15. doi: 10.4049/jimmunol.1200202. Epub 2012 Apr 2.

PMID:
22474023
[PubMed - indexed for MEDLINE]
Free PMC Article

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