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Results: 1 to 20 of 148

1.

Treatment with endotracheal therapeutics after sarin microinstillation inhalation exposure increases blood cholinesterase levels in guinea pigs.

Che MM, Song J, Oguntayo S, Doctor BP, Rezk P, Perkins MW, Sciuto AM, Nambiar MP.

Toxicol Mech Methods. 2012 May;22(4):250-9. doi: 10.3109/15376516.2011.639817. Epub 2011 Dec 7.

PMID:
22145985
[PubMed - indexed for MEDLINE]
2.

Blood and bronchoalveolar lavage fluid acetylcholinesterase levels following microinstillation inhalation exposure to sarin in Guinea pigs.

Che MM, Conti M, Boylan M, Sciuto AM, Gordon RK, Nambiar MP.

Inhal Toxicol. 2008 Jul;20(9):821-8. doi: 10.1080/08958370802050957 .

PMID:
18645722
[PubMed - indexed for MEDLINE]
3.

Post-exposure treatment with nasal atropine methyl bromide protects against microinstillation inhalation exposure to sarin in guinea pigs.

Che MM, Conti M, Chanda S, Boylan M, Sabnekar P, Rezk P, Amari E, Sciuto AM, Gordon RK, Doctor BP, Nambiar MP.

Toxicol Appl Pharmacol. 2009 Sep 15;239(3):251-7. doi: 10.1016/j.taap.2009.06.002. Epub 2009 Jun 11.

PMID:
19523969
[PubMed - indexed for MEDLINE]
4.

Aerosolized scopolamine protects against microinstillation inhalation toxicity to sarin in guinea pigs.

Che MM, Chanda S, Song J, Doctor BP, Rezk PE, Sabnekar P, Perkins MW, Sciuto AM, Nambiar MP.

Toxicol Mech Methods. 2011 Jul;21(6):463-72. doi: 10.3109/15376516.2011.562258.

PMID:
21651338
[PubMed - indexed for MEDLINE]
5.

Endotracheal aerosolization of atropine sulfate protects against soman-induced acute respiratory toxicity in guinea pigs.

Perkins MW, Pierre Z, Rezk P, Song J, Marshall S, Oguntayo S, Morthole V, Sciuto AM, Doctor BP, Nambiar MP.

Inhal Toxicol. 2011 Mar;23(4):182-95. doi: 10.3109/08958378.2011.554458.

PMID:
21456952
[PubMed - indexed for MEDLINE]
6.

Aerosolized delivery of oxime MMB-4 in combination with atropine sulfate protects against soman exposure in guinea pigs.

Perkins MW, Pierre Z, Sabnekar P, Sciuto AM, Song J, Soojhawon I, Oguntayo S, Doctor BP, Nambiar MP.

Inhal Toxicol. 2012 Aug;24(9):539-49. doi: 10.3109/08958378.2012.691912.

PMID:
22860999
[PubMed - indexed for MEDLINE]
7.

Butyrylcholinesterase in guinea pig lung lavage: a novel biomarker to assess lung injury following inhalation exposure to nerve agent VX.

Graham JR, Wright BS, Rezk PE, Gordon RK, Sciuto AM, Nambiar MP.

Inhal Toxicol. 2006 Jun;18(7):493-500.

PMID:
16603480
[PubMed - indexed for MEDLINE]
8.

Gastrointestinal acetylcholinesterase activity following endotracheal microinstillation inhalation exposure to sarin in guinea pigs.

Chanda S, Song J, Rezk P, Sabnekar P, Doctor BP, Sciuto AM, Nambiar MP.

Chem Biol Interact. 2010 Sep 6;187(1-3):309-11. doi: 10.1016/j.cbi.2010.03.011. Epub 2010 Mar 12.

PMID:
20227400
[PubMed - indexed for MEDLINE]
9.

Recombinant paraoxonase 1 protects against sarin and soman toxicity following microinstillation inhalation exposure in guinea pigs.

Valiyaveettil M, Alamneh Y, Rezk P, Perkins MW, Sciuto AM, Doctor BP, Nambiar MP.

Toxicol Lett. 2011 May 10;202(3):203-8. doi: 10.1016/j.toxlet.2011.02.007. Epub 2011 Feb 15.

PMID:
21329748
[PubMed - indexed for MEDLINE]
10.

Effects of 4-pyridine aldoxime on nerve agent-inhibited acetylcholinesterase activity in guinea pigs.

Shih TM, Skovira JW, McDonough JH.

Arch Toxicol. 2009 Dec;83(12):1083-9. doi: 10.1007/s00204-009-0465-4. Epub 2009 Sep 10.

PMID:
19763542
[PubMed - indexed for MEDLINE]
11.

Efficacy of human serum butyrylcholinesterase against sarin vapor.

Saxena A, Sun W, Dabisch PA, Hulet SW, Hastings NB, Jakubowski EM, Mioduszewski RJ, Doctor BP.

Chem Biol Interact. 2008 Sep 25;175(1-3):267-72. doi: 10.1016/j.cbi.2008.05.022. Epub 2008 May 23.

PMID:
18597747
[PubMed - indexed for MEDLINE]
12.

Protective effects of aerosolized scopolamine against soman-induced acute respiratory toxicity in guinea pigs.

Perkins MW, Pierre Z, Rezk P, Song J, Oguntayo S, Morthole V, Sciuto AM, Doctor BP, Nambiar MP.

Int J Toxicol. 2011 Dec;30(6):639-49. doi: 10.1177/1091581811415874. Epub 2011 Sep 29.

PMID:
21960666
[PubMed - indexed for MEDLINE]
13.

Acute sarin exposure causes differential regulation of choline acetyltransferase, acetylcholinesterase, and acetylcholine receptors in the central nervous system of the rat.

Khan WA, Dechkovskaia AM, Herrick EA, Jones KH, Abou-Donia MB.

Toxicol Sci. 2000 Sep;57(1):112-20.

PMID:
10966517
[PubMed - indexed for MEDLINE]
Free Article
14.

Medical countermeasure against respiratory toxicity and acute lung injury following inhalation exposure to chemical warfare nerve agent VX.

Nambiar MP, Gordon RK, Rezk PE, Katos AM, Wajda NA, Moran TS, Steele KE, Doctor BP, Sciuto AM.

Toxicol Appl Pharmacol. 2007 Mar;219(2-3):142-50. Epub 2006 Nov 7.

PMID:
17188727
[PubMed - indexed for MEDLINE]
15.

Acute respiratory toxicity following inhalation exposure to soman in guinea pigs.

Perkins MW, Pierre Z, Rezk P, Sabnekar P, Kabra K, Chanda S, Oguntayo S, Sciuto AM, Doctor BP, Nambiar MP.

Toxicol Appl Pharmacol. 2010 Jun 1;245(2):171-8. doi: 10.1016/j.taap.2010.02.016. Epub 2010 Mar 4.

PMID:
20206646
[PubMed - indexed for MEDLINE]
16.

Differential mRNA expression of acetylcholinesterase in the central nervous system of rats with acute and chronic exposure of sarin & physostigmine.

Bansal I, Waghmare CK, Anand T, Gupta AK, Bhattacharya BK.

J Appl Toxicol. 2009 Jul;29(5):386-94. doi: 10.1002/jat.1424.

PMID:
19283689
[PubMed - indexed for MEDLINE]
17.

Treatment with tertiary oximes prevents seizures and improves survival following sarin intoxication.

Shih TM, Skovira JW, O'Donnell JC, McDonough JH.

J Mol Neurosci. 2010 Jan;40(1-2):63-9. doi: 10.1007/s12031-009-9259-7. Epub 2009 Aug 13.

PMID:
19680820
[PubMed - indexed for MEDLINE]
18.

Equine butyrylcholinesterase protects rats against inhalation exposure to sublethal sarin concentrations.

Bajgar J, Bartosova L, Fusek J, Jun D, Kuca K.

Arh Hig Rada Toksikol. 2006 Dec;57(4):391-5.

PMID:
17265678
[PubMed - indexed for MEDLINE]
19.

Protective efficacy of catalytic bioscavenger, paraoxonase 1 against sarin and soman exposure in guinea pigs.

Valiyaveettil M, Alamneh Y, Rezk P, Biggemann L, Perkins MW, Sciuto AM, Doctor BP, Nambiar MP.

Biochem Pharmacol. 2011 Mar 15;81(6):800-9. doi: 10.1016/j.bcp.2010.12.024. Epub 2011 Jan 8.

PMID:
21219877
[PubMed - indexed for MEDLINE]
20.

Pretreatment with human serum butyrylcholinesterase alone prevents cardiac abnormalities, seizures, and death in Göttingen minipigs exposed to sarin vapor.

Saxena A, Sun W, Dabisch PA, Hulet SW, Hastings NB, Jakubowski EM, Mioduszewski RJ, Doctor BP.

Biochem Pharmacol. 2011 Dec 15;82(12):1984-93. doi: 10.1016/j.bcp.2011.09.019. Epub 2011 Sep 24.

PMID:
21968035
[PubMed - indexed for MEDLINE]

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