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Similar articles for PubMed (Select 22145856)


Targeting of pro-apoptotic TLR adaptor SARM to mitochondria: definition of the critical region and residues in the signal sequence.

Panneerselvam P, Singh LP, Ho B, Chen J, Ding JL.

Biochem J. 2012 Mar 1;442(2):263-71. doi: 10.1042/BJ20111653.


SARM: a novel Toll-like receptor adaptor, is functionally conserved from arthropod to human.

Belinda LW, Wei WX, Hanh BT, Lei LX, Bow H, Ling DJ.

Mol Immunol. 2008 Mar;45(6):1732-42. Epub 2007 Nov 5.


T-cell death following immune activation is mediated by mitochondria-localized SARM.

Panneerselvam P, Singh LP, Selvarajan V, Chng WJ, Ng SB, Tan NS, Ho B, Chen J, Ding JL.

Cell Death Differ. 2013 Mar;20(3):478-89. doi: 10.1038/cdd.2012.144. Epub 2012 Nov 23.


The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling.

Carty M, Goodbody R, Schröder M, Stack J, Moynagh PN, Bowie AG.

Nat Immunol. 2006 Oct;7(10):1074-81. Epub 2006 Sep 10.


UXT plays dual opposing roles on SARM-induced apoptosis.

Sethurathinam S, Singh LP, Panneerselvam P, Byrne B, Ding JL.

FEBS Lett. 2013 Oct 11;587(20):3296-302. doi: 10.1016/j.febslet.2013.08.033. Epub 2013 Sep 8.


Amphioxus SARM involved in neural development may function as a suppressor of TLR signaling.

Yuan S, Wu K, Yang M, Xu L, Huang L, Liu H, Tao X, Huang S, Xu A.

J Immunol. 2010 Jun 15;184(12):6874-81. doi: 10.4049/jimmunol.0903675. Epub 2010 May 14.


SARM inhibits both TRIF- and MyD88-mediated AP-1 activation.

Peng J, Yuan Q, Lin B, Panneerselvam P, Wang X, Luan XL, Lim SK, Leung BP, Ho B, Ding JL.

Eur J Immunol. 2010 Jun;40(6):1738-47. doi: 10.1002/eji.200940034.


Sarm1-mediated axon degeneration requires both SAM and TIR interactions.

Gerdts J, Summers DW, Sasaki Y, DiAntonio A, Milbrandt J.

J Neurosci. 2013 Aug 14;33(33):13569-80. doi: 10.1523/JNEUROSCI.1197-13.2013.


Evolution of the TIR domain-containing adaptors in humans: swinging between constraint and adaptation.

Fornarino S, Laval G, Barreiro LB, Manry J, Vasseur E, Quintana-Murci L.

Mol Biol Evol. 2011 Nov;28(11):3087-97. doi: 10.1093/molbev/msr137. Epub 2011 Jun 9.


Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis.

Linseman DA, Butts BD, Precht TA, Phelps RA, Le SS, Laessig TA, Bouchard RJ, Florez-McClure ML, Heidenreich KA.

J Neurosci. 2004 Nov 3;24(44):9993-10002.


The Toll-IL-1 receptor adaptor family grows to five members.

O'Neill LA, Fitzgerald KA, Bowie AG.

Trends Immunol. 2003 Jun;24(6):286-90. Review.


Identification of nuclear export signals in antizyme-1.

Murai N, Murakami Y, Matsufuji S.

J Biol Chem. 2003 Nov 7;278(45):44791-8. Epub 2003 Aug 26.


Distinct domains for anti- and pro-apoptotic activities of IEX-1.

Shen L, Guo J, Santos-Berrios C, Wu MX.

J Biol Chem. 2006 Jun 2;281(22):15304-11. Epub 2006 Mar 27.


SARM regulates CCL5 production in macrophages by promoting the recruitment of transcription factors and RNA polymerase II to the Ccl5 promoter.

Gürtler C, Carty M, Kearney J, Schattgen SA, Ding A, Fitzgerald KA, Bowie AG.

J Immunol. 2014 May 15;192(10):4821-32. doi: 10.4049/jimmunol.1302980. Epub 2014 Apr 7.


Identification and characterization of the mitochondrial targeting sequence and mechanism in human citrate synthase.

Cheng TL, Liao CC, Tsai WH, Lin CC, Yeh CW, Teng CF, Chang WT.

J Cell Biochem. 2009 Aug 1;107(5):1002-15. doi: 10.1002/jcb.22200.


Characterization of the signal that directs Bcl-x(L), but not Bcl-2, to the mitochondrial outer membrane.

Kaufmann T, Schlipf S, Sanz J, Neubert K, Stein R, Borner C.

J Cell Biol. 2003 Jan 6;160(1):53-64. Epub 2003 Jan 6.


The immune adaptor molecule SARM modulates tumor necrosis factor alpha production and microglia activation in the brainstem and restricts West Nile Virus pathogenesis.

Szretter KJ, Samuel MA, Gilfillan S, Fuchs A, Colonna M, Diamond MS.

J Virol. 2009 Sep;83(18):9329-38. doi: 10.1128/JVI.00836-09. Epub 2009 Jul 8.

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