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Results: 1 to 20 of 112

1.

Identification of a core member of the SWI/SNF complex, BAF155/SMARCC1, as a human tumor suppressor gene.

DelBove J, Rosson G, Strobeck M, Chen J, Archer TK, Wang W, Knudsen ES, Weissman BE.

Epigenetics. 2011 Dec;6(12):1444-53. doi: 10.4161/epi.6.12.18492.

PMID:
22139574
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Oncogenesis caused by loss of the SNF5 tumor suppressor is dependent on activity of BRG1, the ATPase of the SWI/SNF chromatin remodeling complex.

Wang X, Sansam CG, Thom CS, Metzger D, Evans JA, Nguyen PT, Roberts CW.

Cancer Res. 2009 Oct 15;69(20):8094-101. doi: 10.1158/0008-5472.CAN-09-0733. Epub 2009 Sep 29.

PMID:
19789351
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

BAF60a interacts with p53 to recruit the SWI/SNF complex.

Oh J, Sohn DH, Ko M, Chung H, Jeon SH, Seong RH.

J Biol Chem. 2008 May 2;283(18):11924-34. doi: 10.1074/jbc.M705401200. Epub 2008 Feb 26.

PMID:
18303029
[PubMed - indexed for MEDLINE]
Free Article
4.

Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation.

Isakoff MS, Sansam CG, Tamayo P, Subramanian A, Evans JA, Fillmore CM, Wang X, Biegel JA, Pomeroy SL, Mesirov JP, Roberts CW.

Proc Natl Acad Sci U S A. 2005 Dec 6;102(49):17745-50. Epub 2005 Nov 21.

PMID:
16301525
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Loss of the INI1 tumor suppressor does not impair the expression of multiple BRG1-dependent genes or the assembly of SWI/SNF enzymes.

Doan DN, Veal TM, Yan Z, Wang W, Jones SN, Imbalzano AN.

Oncogene. 2004 Apr 22;23(19):3462-73.

PMID:
14990991
[PubMed - indexed for MEDLINE]
6.

The BRG1- and hBRM-associated factor BAF57 induces apoptosis by stimulating expression of the cylindromatosis tumor suppressor gene.

Wang L, Baiocchi RA, Pal S, Mosialos G, Caligiuri M, Sif S.

Mol Cell Biol. 2005 Sep;25(18):7953-65.

PMID:
16135788
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Characterization of SWI/SNF protein expression in human breast cancer cell lines and other malignancies.

Decristofaro MF, Betz BL, Rorie CJ, Reisman DN, Wang W, Weissman BE.

J Cell Physiol. 2001 Jan;186(1):136-45.

PMID:
11147808
[PubMed - indexed for MEDLINE]
8.

BRG1 mutations found in human cancer cell lines inactivate Rb-mediated cell-cycle arrest.

Bartlett C, Orvis TJ, Rosson GS, Weissman BE.

J Cell Physiol. 2011 Aug;226(8):1989-97. doi: 10.1002/jcp.22533.

PMID:
21520050
[PubMed - indexed for MEDLINE]
9.

Inactivating mutations in SWI/SNF chromatin remodeling genes in human cancer.

Oike T, Ogiwara H, Nakano T, Yokota J, Kohno T.

Jpn J Clin Oncol. 2013 Sep;43(9):849-55. doi: 10.1093/jjco/hyt101. Epub 2013 Jul 30.

PMID:
23904343
[PubMed - indexed for MEDLINE]
Free Article
10.

SRG3 interacts directly with the major components of the SWI/SNF chromatin remodeling complex and protects them from proteasomal degradation.

Sohn DH, Lee KY, Lee C, Oh J, Chung H, Jeon SH, Seong RH.

J Biol Chem. 2007 Apr 6;282(14):10614-24. Epub 2007 Jan 24.

PMID:
17255092
[PubMed - indexed for MEDLINE]
Free Article
11.
12.

Inhibition of expression of the chromatin remodeling gene, SNF2L, selectively leads to DNA damage, growth inhibition, and cancer cell death.

Ye Y, Xiao Y, Wang W, Wang Q, Yearsley K, Wani AA, Yan Q, Gao JX, Shetuni BS, Barsky SH.

Mol Cancer Res. 2009 Dec;7(12):1984-99. doi: 10.1158/1541-7786.MCR-09-0119. Epub 2009 Dec 8.

PMID:
19996304
[PubMed - indexed for MEDLINE]
Free Article
13.

The requirement for SNF5/INI1 in adipocyte differentiation highlights new features of malignant rhabdoid tumors.

Caramel J, Medjkane S, Quignon F, Delattre O.

Oncogene. 2008 Mar 27;27(14):2035-44. Epub 2007 Oct 8.

PMID:
17922027
[PubMed - indexed for MEDLINE]
14.

Epigenetic inactivation of the tumor suppressor BIN1 drives proliferation of SNF5-deficient tumors.

McKenna ES, Tamayo P, Cho YJ, Tillman EJ, Mora-Blanco EL, Sansam CG, Koellhoffer EC, Pomeroy SL, Roberts CW.

Cell Cycle. 2012 May 15;11(10):1956-65. doi: 10.4161/cc.20280. Epub 2012 May 15.

PMID:
22544318
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines.

Wong AK, Shanahan F, Chen Y, Lian L, Ha P, Hendricks K, Ghaffari S, Iliev D, Penn B, Woodland AM, Smith R, Salada G, Carillo A, Laity K, Gupte J, Swedlund B, Tavtigian SV, Teng DH, Lees E.

Cancer Res. 2000 Nov 1;60(21):6171-7.

PMID:
11085541
[PubMed - indexed for MEDLINE]
Free Article
16.

Increased DNA damage sensitivity and apoptosis in cells lacking the Snf5/Ini1 subunit of the SWI/SNF chromatin remodeling complex.

Klochendler-Yeivin A, Picarsky E, Yaniv M.

Mol Cell Biol. 2006 Apr;26(7):2661-74.

PMID:
16537910
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Human SNF5/INI1, a component of the human SWI/SNF chromatin remodeling complex, promotes nucleotide excision repair by influencing ATM recruitment and downstream H2AX phosphorylation.

Ray A, Mir SN, Wani G, Zhao Q, Battu A, Zhu Q, Wang QE, Wani AA.

Mol Cell Biol. 2009 Dec;29(23):6206-19. doi: 10.1128/MCB.00503-09. Epub 2009 Oct 5.

PMID:
19805520
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Epigenetics and cancer: altered chromatin remodeling via Snf5 loss leads to aberrant cell cycle regulation.

Sansam CG, Roberts CW.

Cell Cycle. 2006 Mar;5(6):621-4. Epub 2006 Mar 15. Review.

PMID:
16582616
[PubMed - indexed for MEDLINE]
Free Article
19.

Aurora A is a repressed effector target of the chromatin remodeling protein INI1/hSNF5 required for rhabdoid tumor cell survival.

Lee S, Cimica V, Ramachandra N, Zagzag D, Kalpana GV.

Cancer Res. 2011 May 1;71(9):3225-35. doi: 10.1158/0008-5472.CAN-10-2167. Epub 2011 Apr 26.

PMID:
21521802
[PubMed - indexed for MEDLINE]
Free Article
20.

Genetic and epigenetic alterations of BRG1 promote oral cancer development.

Gunduz E, Gunduz M, Ouchida M, Nagatsuka H, Beder L, Tsujigiwa H, Fukushima K, Nishizaki K, Shimizu K, Nagai N.

Int J Oncol. 2005 Jan;26(1):201-10.

PMID:
15586241
[PubMed - indexed for MEDLINE]
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