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Items: 1 to 20 of 121

1.

Dnmt3a is essential for hematopoietic stem cell differentiation.

Challen GA, Sun D, Jeong M, Luo M, Jelinek J, Berg JS, Bock C, Vasanthakumar A, Gu H, Xi Y, Liang S, Lu Y, Darlington GJ, Meissner A, Issa JP, Godley LA, Li W, Goodell MA.

Nat Genet. 2011 Dec 4;44(1):23-31. doi: 10.1038/ng.1009.

2.

De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells.

Tadokoro Y, Ema H, Okano M, Li E, Nakauchi H.

J Exp Med. 2007 Apr 16;204(4):715-22. Epub 2007 Apr 9.

3.

Dnmt3a and Dnmt3b have overlapping and distinct functions in hematopoietic stem cells.

Challen GA, Sun D, Mayle A, Jeong M, Luo M, Rodriguez B, Mallaney C, Celik H, Yang L, Xia Z, Cullen S, Berg J, Zheng Y, Darlington GJ, Li W, Goodell MA.

Cell Stem Cell. 2014 Sep 4;15(3):350-64. doi: 10.1016/j.stem.2014.06.018. Epub 2014 Aug 14.

4.

Dnmt3a silences hematopoietic stem cell self-renewal.

Trowbridge JJ, Orkin SH.

Nat Genet. 2011 Dec 27;44(1):13-4. doi: 10.1038/ng.1043.

PMID:
22200773
5.

CpG sites preferentially methylated by Dnmt3a in vivo.

Oka M, Rodić N, Graddy J, Chang LJ, Terada N.

J Biol Chem. 2006 Apr 14;281(15):9901-8. Epub 2006 Jan 26.

6.
7.

Regulation of DNA methylation activity through Dnmt3L promoter methylation by Dnmt3 enzymes in embryonic development.

Hu YG, Hirasawa R, Hu JL, Hata K, Li CL, Jin Y, Chen T, Li E, Rigolet M, Viegas-Péquignot E, Sasaki H, Xu GL.

Hum Mol Genet. 2008 Sep 1;17(17):2654-64. doi: 10.1093/hmg/ddn165. Epub 2008 Jun 10.

8.

miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a.

Hu W, Dooley J, Chung SS, Chandramohan D, Cimmino L, Mukherjee S, Mason CE, de Strooper B, Liston A, Park CY.

Blood. 2015 Apr 2;125(14):2206-16. doi: 10.1182/blood-2014-06-585273. Epub 2015 Jan 29.

10.

The de novo methyltransferases DNMT3a and DNMT3b target the murine gammaherpesvirus immediate-early gene 50 promoter during establishment of latency.

Gray KS, Forrest JC, Speck SH.

J Virol. 2010 May;84(10):4946-59. doi: 10.1128/JVI.00060-10. Epub 2010 Mar 3.

11.

Identification of DNA methyltransferase 3a as a T cell receptor-induced regulator of Th1 and Th2 differentiation.

Gamper CJ, Agoston AT, Nelson WG, Powell JD.

J Immunol. 2009 Aug 15;183(4):2267-76. doi: 10.4049/jimmunol.0802960. Epub 2009 Jul 22.

12.
13.

DNA methylation is required for silencing of ant4, an adenine nucleotide translocase selectively expressed in mouse embryonic stem cells and germ cells.

Rodić N, Oka M, Hamazaki T, Murawski MR, Jorgensen M, Maatouk DM, Resnick JL, Li E, Terada N.

Stem Cells. 2005 Oct;23(9):1314-23. Epub 2005 Jul 28.

14.

Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b.

Tsumura A, Hayakawa T, Kumaki Y, Takebayashi S, Sakaue M, Matsuoka C, Shimotohno K, Ishikawa F, Li E, Ueda HR, Nakayama J, Okano M.

Genes Cells. 2006 Jul;11(7):805-14.

15.

Transition of mouse de novo methyltransferases expression from Dnmt3b to Dnmt3a during neural progenitor cell development.

Watanabe D, Uchiyama K, Hanaoka K.

Neuroscience. 2006 Oct 27;142(3):727-37. Epub 2006 Sep 14.

PMID:
16973295
16.

Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression.

Gao Q, Steine EJ, Barrasa MI, Hockemeyer D, Pawlak M, Fu D, Reddy S, Bell GW, Jaenisch R.

Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):18061-6. doi: 10.1073/pnas.1114946108. Epub 2011 Oct 19.

17.

Synergistic function of DNA methyltransferases Dnmt3a and Dnmt3b in the methylation of Oct4 and Nanog.

Li JY, Pu MT, Hirasawa R, Li BZ, Huang YN, Zeng R, Jing NH, Chen T, Li E, Sasaki H, Xu GL.

Mol Cell Biol. 2007 Dec;27(24):8748-59. Epub 2007 Oct 15.

18.

Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation.

Mayle A, Yang L, Rodriguez B, Zhou T, Chang E, Curry CV, Challen GA, Li W, Wheeler D, Rebel VI, Goodell MA.

Blood. 2015 Jan 22;125(4):629-38.

19.

Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting.

Kaneda M, Okano M, Hata K, Sado T, Tsujimoto N, Li E, Sasaki H.

Nature. 2004 Jun 24;429(6994):900-3.

PMID:
15215868
20.

De novo methylation of MMLV provirus in embryonic stem cells: CpG versus non-CpG methylation.

Dodge JE, Ramsahoye BH, Wo ZG, Okano M, Li E.

Gene. 2002 May 1;289(1-2):41-8.

PMID:
12036582
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