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Bacterial cis-2-unsaturated fatty acids found in the cystic fibrosis airway modulate virulence and persistence of Pseudomonas aeruginosa.

Twomey KB, O'Connell OJ, McCarthy Y, Dow JM, O'Toole GA, Plant BJ, Ryan RP.

ISME J. 2012 May;6(5):939-50. doi: 10.1038/ismej.2011.167. Epub 2011 Dec 1.


Interspecies signalling via the Stenotrophomonas maltophilia diffusible signal factor influences biofilm formation and polymyxin tolerance in Pseudomonas aeruginosa.

Ryan RP, Fouhy Y, Garcia BF, Watt SA, Niehaus K, Yang L, Tolker-Nielsen T, Dow JM.

Mol Microbiol. 2008 Apr;68(1):75-86. doi: 10.1111/j.1365-2958.2008.06132.x. Epub 2008 Feb 28.


Communication with a growing family: diffusible signal factor (DSF) signaling in bacteria.

Ryan RP, Dow JM.

Trends Microbiol. 2011 Mar;19(3):145-52. doi: 10.1016/j.tim.2010.12.003. Epub 2011 Jan 10.


Modelling co-infection of the cystic fibrosis lung by Pseudomonas aeruginosa and Burkholderia cenocepacia reveals influences on biofilm formation and host response.

Bragonzi A, Farulla I, Paroni M, Twomey KB, Pirone L, Lorè NI, Bianconi I, Dalmastri C, Ryan RP, Bevivino A.

PLoS One. 2012;7(12):e52330. doi: 10.1371/journal.pone.0052330. Epub 2012 Dec 21.


Pseudomonas aeruginosa alginate promotes Burkholderia cenocepacia persistence in cystic fibrosis transmembrane conductance regulator knockout mice.

Chattoraj SS, Murthy R, Ganesan S, Goldberg JB, Zhao Y, Hershenson MB, Sajjan US.

Infect Immun. 2010 Mar;78(3):984-93. doi: 10.1128/IAI.01192-09. Epub 2010 Jan 4.


In vitro analysis of tobramycin-treated Pseudomonas aeruginosa biofilms on cystic fibrosis-derived airway epithelial cells.

Anderson GG, Moreau-Marquis S, Stanton BA, O'Toole GA.

Infect Immun. 2008 Apr;76(4):1423-33. doi: 10.1128/IAI.01373-07. Epub 2008 Jan 22.


Combination antibiotic susceptibility of biofilm-grown Burkholderia cepacia and Pseudomonas aeruginosa isolated from patients with pulmonary exacerbations of cystic fibrosis.

Dales L, Ferris W, Vandemheen K, Aaron SD.

Eur J Clin Microbiol Infect Dis. 2009 Oct;28(10):1275-9. doi: 10.1007/s10096-009-0774-9. Epub 2009 Jul 3.


Conditions associated with the cystic fibrosis defect promote chronic Pseudomonas aeruginosa infection.

Staudinger BJ, Muller JF, Halldórsson S, Boles B, Angermeyer A, Nguyen D, Rosen H, Baldursson O, Gottfreðsson M, Guðmundsson GH, Singh PK.

Am J Respir Crit Care Med. 2014 Apr 1;189(7):812-24. doi: 10.1164/rccm.201312-2142OC.


The DeltaF508-CFTR mutation results in increased biofilm formation by Pseudomonas aeruginosa by increasing iron availability.

Moreau-Marquis S, Bomberger JM, Anderson GG, Swiatecka-Urban A, Ye S, O'Toole GA, Stanton BA.

Am J Physiol Lung Cell Mol Physiol. 2008 Jul;295(1):L25-37. doi: 10.1152/ajplung.00391.2007. Epub 2008 Mar 21.


Potential novel therapeutic strategies in cystic fibrosis: antimicrobial and anti-biofilm activity of natural and designed α-helical peptides against Staphylococcus aureus, Pseudomonas aeruginosa, and Stenotrophomonas maltophilia.

Pompilio A, Crocetta V, Scocchi M, Pomponio S, Di Vincenzo V, Mardirossian M, Gherardi G, Fiscarelli E, Dicuonzo G, Gennaro R, Di Bonaventura G.

BMC Microbiol. 2012 Jul 23;12:145. doi: 10.1186/1471-2180-12-145.


Use of artificial sputum medium to test antibiotic efficacy against Pseudomonas aeruginosa in conditions more relevant to the cystic fibrosis lung.

Kirchner S, Fothergill JL, Wright EA, James CE, Mowat E, Winstanley C.

J Vis Exp. 2012 Jun 5;(64):e3857. doi: 10.3791/3857.


Cathelicidin peptides inhibit multiply antibiotic-resistant pathogens from patients with cystic fibrosis.

Saiman L, Tabibi S, Starner TD, San Gabriel P, Winokur PL, Jia HP, McCray PB Jr, Tack BF.

Antimicrob Agents Chemother. 2001 Oct;45(10):2838-44.


In vitro interactions of tobramycin with various nonantibiotics against Pseudomonas aeruginosa and Burkholderia cenocepacia.

Treerat P, Widmer F, Middleton PG, Iredell J, George AM.

FEMS Microbiol Lett. 2008 Aug;285(1):40-50. doi: 10.1111/j.1574-6968.2008.01219.x. Epub 2008 May 29.


Modulation of Pseudomonas aeruginosa gene expression by host microflora through interspecies communication.

Duan K, Dammel C, Stein J, Rabin H, Surette MG.

Mol Microbiol. 2003 Dec;50(5):1477-91.


In vitro evaluation of tobramycin and aztreonam versus Pseudomonas aeruginosa biofilms on cystic fibrosis-derived human airway epithelial cells.

Yu Q, Griffin EF, Moreau-Marquis S, Schwartzman JD, Stanton BA, O'Toole GA.

J Antimicrob Chemother. 2012 Nov;67(11):2673-81. doi: 10.1093/jac/dks296. Epub 2012 Jul 26.


Inhibition of co-colonizing cystic fibrosis-associated pathogens by Pseudomonas aeruginosa and Burkholderia multivorans.

Costello A, Reen FJ, O'Gara F, Callaghan M, McClean S.

Microbiology. 2014 Jul;160(Pt 7):1474-87. doi: 10.1099/mic.0.074203-0. Epub 2014 Apr 30.

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