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Items: 1 to 20 of 78


Severely impaired learning and altered neuronal morphology in mice lacking NMDA receptors in medium spiny neurons.

Beutler LR, Eldred KC, Quintana A, Keene CD, Rose SE, Postupna N, Montine TJ, Palmiter RD.

PLoS One. 2011;6(11):e28168. doi: 10.1371/journal.pone.0028168. Epub 2011 Nov 21.


The contribution of NMDA receptor signaling in the corticobasal ganglia reward network to appetitive Pavlovian learning.

Parker JG, Beutler LR, Palmiter RD.

J Neurosci. 2011 Aug 3;31(31):11362-9. doi: 10.1523/JNEUROSCI.2411-11.2011.


Balanced NMDA receptor activity in dopamine D1 receptor (D1R)- and D2R-expressing medium spiny neurons is required for amphetamine sensitization.

Beutler LR, Wanat MJ, Quintana A, Sanz E, Bamford NS, Zweifel LS, Palmiter RD.

Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):4206-11. doi: 10.1073/pnas.1101424108. Epub 2011 Feb 22.


Long-lasting NMDA receptor-mediated EPSCs in mouse striatal medium spiny neurons.

Logan SM, Partridge JG, Matta JA, Buonanno A, Vicini S.

J Neurophysiol. 2007 Nov;98(5):2693-704. Epub 2007 Sep 5.


Mitigation of augmented extrasynaptic NMDAR signaling and apoptosis in cortico-striatal co-cultures from Huntington's disease mice.

Milnerwood AJ, Kaufman AM, Sepers MD, Gladding CM, Zhang L, Wang L, Fan J, Coquinco A, Qiao JY, Lee H, Wang YT, Cynader M, Raymond LA.

Neurobiol Dis. 2012 Oct;48(1):40-51. doi: 10.1016/j.nbd.2012.05.013. Epub 2012 Jun 2.


Concomitant deficits in working memory and fear extinction are functionally dissociated from reduced anxiety in metabotropic glutamate receptor 7-deficient mice.

Callaerts-Vegh Z, Beckers T, Ball SM, Baeyens F, Callaerts PF, Cryan JF, Molnar E, D'Hooge R.

J Neurosci. 2006 Jun 14;26(24):6573-82.


Polyglutamine-modulated striatal calpain activity in YAC transgenic huntington disease mouse model: impact on NMDA receptor function and toxicity.

Cowan CM, Fan MM, Fan J, Shehadeh J, Zhang LY, Graham RK, Hayden MR, Raymond LA.

J Neurosci. 2008 Nov 26;28(48):12725-35. doi: 10.1523/JNEUROSCI.4619-08.2008.


Role of motor cortex NMDA receptors in learning-dependent synaptic plasticity of behaving mice.

Hasan MT, Hernández-González S, Dogbevia G, Treviño M, Bertocchi I, Gruart A, Delgado-García JM.

Nat Commun. 2013;4:2258. doi: 10.1038/ncomms3258. Erratum in: Nat Commun. 2013;4:2831.


Hyperfunction of dopaminergic and serotonergic neuronal systems in mice lacking the NMDA receptor epsilon1 subunit.

Miyamoto Y, Yamada K, Noda Y, Mori H, Mishina M, Nabeshima T.

J Neurosci. 2001 Jan 15;21(2):750-7.


Enhanced striatal NR2B-containing N-methyl-D-aspartate receptor-mediated synaptic currents in a mouse model of Huntington disease.

Li L, Murphy TH, Hayden MR, Raymond LA.

J Neurophysiol. 2004 Nov;92(5):2738-46. Epub 2004 Jul 7.


Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons.

Kaufman AM, Milnerwood AJ, Sepers MD, Coquinco A, She K, Wang L, Lee H, Craig AM, Cynader M, Raymond LA.

J Neurosci. 2012 Mar 21;32(12):3992-4003. doi: 10.1523/JNEUROSCI.4129-11.2012.


Allosteric modulation of NMDA receptors alters neurotransmission in the striatum of a mouse model of Parkinson's disease.

Feng ZJ, Zhang X, Chergui K.

Exp Neurol. 2014 May;255:154-60. doi: 10.1016/j.expneurol.2014.03.001. Epub 2014 Mar 12.


Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons.

Pisani A, Gubellini P, Bonsi P, Conquet F, Picconi B, Centonze D, Bernardi G, Calabresi P.

Neuroscience. 2001;106(3):579-87.


Impaired appetitively as well as aversively motivated behaviors and learning in PDE10A-deficient mice suggest a role for striatal signaling in evaluative salience attribution.

Piccart E, Gantois I, Laeremans A, de Hoogt R, Meert T, Vanhoof G, Arckens L, D'Hooge R.

Neurobiol Learn Mem. 2011 Mar;95(3):260-9. doi: 10.1016/j.nlm.2010.11.018. Epub 2010 Dec 2.


Specific contributions of N-methyl-D-aspartate receptors in the dorsal striatum to cognitive flexibility.

Darvas M, Palmiter RD.

Neuroscience. 2015 Jan 22;284:934-42. doi: 10.1016/j.neuroscience.2014.11.011. Epub 2014 Nov 15.


Mitochondrial sensitivity and altered calcium handling underlie enhanced NMDA-induced apoptosis in YAC128 model of Huntington's disease.

Fernandes HB, Baimbridge KG, Church J, Hayden MR, Raymond LA.

J Neurosci. 2007 Dec 12;27(50):13614-23.


Lower sensitivity to stress and altered monoaminergic neuronal function in mice lacking the NMDA receptor epsilon 4 subunit.

Miyamoto Y, Yamada K, Noda Y, Mori H, Mishina M, Nabeshima T.

J Neurosci. 2002 Mar 15;22(6):2335-42.


Interaction of postsynaptic density protein-95 with NMDA receptors influences excitotoxicity in the yeast artificial chromosome mouse model of Huntington's disease.

Fan J, Cowan CM, Zhang LY, Hayden MR, Raymond LA.

J Neurosci. 2009 Sep 2;29(35):10928-38. doi: 10.1523/JNEUROSCI.2491-09.2009.


P38 MAPK is involved in enhanced NMDA receptor-dependent excitotoxicity in YAC transgenic mouse model of Huntington disease.

Fan J, Gladding CM, Wang L, Zhang LY, Kaufman AM, Milnerwood AJ, Raymond LA.

Neurobiol Dis. 2012 Mar;45(3):999-1009. doi: 10.1016/j.nbd.2011.12.019. Epub 2011 Dec 14.

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