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Aldehyde dehydrogenase activity is a biomarker of primitive normal human mammary luminal cells.

Eirew P, Kannan N, Knapp DJ, Vaillant F, Emerman JT, Lindeman GJ, Visvader JE, Eaves CJ.

Stem Cells. 2012 Feb;30(2):344-8. doi: 10.1002/stem.1001.


Aldehyde dehydrogenase and estrogen receptor define a hierarchy of cellular differentiation in the normal human mammary epithelium.

Honeth G, Lombardi S, Ginestier C, Hur M, Marlow R, Buchupalli B, Shinomiya I, Gazinska P, Bombelli S, Ramalingam V, Purushotham AD, Pinder SE, Dontu G.

Breast Cancer Res. 2014 May 27;16(3):R52. doi: 10.1186/bcr3663.


ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome.

Ginestier C, Hur MH, Charafe-Jauffret E, Monville F, Dutcher J, Brown M, Jacquemier J, Viens P, Kleer CG, Liu S, Schott A, Hayes D, Birnbaum D, Wicha MS, Dontu G.

Cell Stem Cell. 2007 Nov;1(5):555-67. doi: 10.1016/j.stem.2007.08.014.


Characterization of aldehyde dehydrogenase isozymes in ovarian cancer tissues and sphere cultures.

Saw YT, Yang J, Ng SK, Liu S, Singh S, Singh M, Welch WR, Tsuda H, Fong WP, Thompson D, Vasiliou V, Berkowitz RS, Ng SW.

BMC Cancer. 2012 Aug 1;12:329.


High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability.

Croker AK, Goodale D, Chu J, Postenka C, Hedley BD, Hess DA, Allan AL.

J Cell Mol Med. 2009 Aug;13(8B):2236-52. doi: 10.1111/j.1582-4934.2008.00455.x. Epub 2008 Aug 4.


Cell hierarchy and lineage commitment in the bovine mammary gland.

Rauner G, Barash I.

PLoS One. 2012;7(1):e30113. doi: 10.1371/journal.pone.0030113. Epub 2012 Jan 13.


Dual SP/ALDH functionalities refine the human hematopoietic Lin-CD34+CD38- stem/progenitor cell compartment.

Pierre-Louis O, Clay D, Brunet de la Grange P, Blazsek I, Desterke C, Guerton B, Blondeau C, Malfuson JV, Prat M, Bennaceur-Griscelli A, Lataillade JJ, Le Bousse-Kerdil├Ęs MC.

Stem Cells. 2009 Oct;27(10):2552-62. doi: 10.1002/stem.186.


Aldehyde dehydrogenase activity of breast cancer stem cells is primarily due to isoform ALDH1A3 and its expression is predictive of metastasis.

Marcato P, Dean CA, Pan D, Araslanova R, Gillis M, Joshi M, Helyer L, Pan L, Leidal A, Gujar S, Giacomantonio CA, Lee PW.

Stem Cells. 2011 Jan;29(1):32-45. doi: 10.1002/stem.563.


Aldehyde dehydrogenase (ALDH) 3A1 expression by the human keratocyte and its repair phenotypes.

Pei Y, Reins RY, McDermott AM.

Exp Eye Res. 2006 Nov;83(5):1063-73. Epub 2006 Jul 5.


Aldehyde dehydrogenase activity promotes survival of human muscle precursor cells.

Jean E, Laoudj-Chenivesse D, Notarnicola C, Rouger K, Serratrice N, Bonnieu A, Gay S, Bacou F, Duret C, Carnac G.

J Cell Mol Med. 2011 Jan;15(1):119-33. doi: 10.1111/j.1582-4934.2009.00942.x.


Distinct expression patterns and roles of aldehyde dehydrogenases in normal oral mucosa keratinocytes: differential inhibitory effects of a pharmacological inhibitor and RNAi-mediated knockdown on cellular phenotype and epithelial morphology.

Kato H, Izumi K, Saito T, Ohnuki H, Terada M, Kawano Y, Nozawa-Inoue K, Saito C, Maeda T.

Histochem Cell Biol. 2013 Jun;139(6):847-62. doi: 10.1007/s00418-012-1064-7. Epub 2012 Dec 19.


Identification of a primitive brain-derived neural stem cell population based on aldehyde dehydrogenase activity.

Corti S, Locatelli F, Papadimitriou D, Donadoni C, Salani S, Del Bo R, Strazzer S, Bresolin N, Comi GP.

Stem Cells. 2006 Apr;24(4):975-85. Epub 2005 Nov 17.


Extended flow cytometry characterization of normal bone marrow progenitor cells by simultaneous detection of aldehyde dehydrogenase and early hematopoietic antigens: implication for erythroid differentiation studies.

Mirabelli P, Di Noto R, Lo Pardo C, Morabito P, Abate G, Gorrese M, Raia M, Pascariello C, Scalia G, Gemei M, Mariotti E, Del Vecchio L.

BMC Physiol. 2008 May 29;8:13. doi: 10.1186/1472-6793-8-13.


Improved purification of hematopoietic stem cells based on their elevated aldehyde dehydrogenase activity.

Christ O, Lucke K, Imren S, Leung K, Hamilton M, Eaves A, Smith C, Eaves C.

Haematologica. 2007 Sep;92(9):1165-72. Epub 2007 Aug 1.


Characterization of cardiac-resident progenitor cells expressing high aldehyde dehydrogenase activity.

Roehrich ME, Spicher A, Milano G, Vassalli G.

Biomed Res Int. 2013;2013:503047. doi: 10.1155/2013/503047. Epub 2013 Jan 31.


Distinct hematopoietic progenitor compartments are delineated by the expression of aldehyde dehydrogenase and CD34.

Storms RW, Green PD, Safford KM, Niedzwiecki D, Cogle CR, Colvin OM, Chao NJ, Rice HE, Smith CA.

Blood. 2005 Jul 1;106(1):95-102. Epub 2005 Mar 24.


Characterization and clinical relevance of ALDHbright populations in prostate cancer.

Le Magnen C, Bubendorf L, Rentsch CA, Mengus C, Gsponer J, Zellweger T, Rieken M, Thalmann GN, Cecchini MG, Germann M, Bachmann A, Wyler S, Heberer M, Spagnoli GC.

Clin Cancer Res. 2013 Oct 1;19(19):5361-71. doi: 10.1158/1078-0432.CCR-12-2857. Epub 2013 Aug 22.


Aldehyde dehydrogenase as a marker for stem cells.

Moreb JS.

Curr Stem Cell Res Ther. 2008 Dec;3(4):237-46. Review.

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