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Results: 1 to 20 of 97

1.

Cytokinesis failure due to derailed integrin traffic induces aneuploidy and oncogenic transformation in vitro and in vivo.

Högnäs G, Tuomi S, Veltel S, Mattila E, Murumägi A, Edgren H, Kallioniemi O, Ivaska J.

Oncogene. 2012 Aug 2;31(31):3597-606. doi: 10.1038/onc.2011.527. Epub 2011 Nov 28.

PMID:
22120710
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Tetraploid cells from cytokinesis failure induce aneuploidy and spontaneous transformation of mouse ovarian surface epithelial cells.

Lv L, Zhang T, Yi Q, Huang Y, Wang Z, Hou H, Zhang H, Zheng W, Hao Q, Guo Z, Cooke HJ, Shi Q.

Cell Cycle. 2012 Aug 1;11(15):2864-75. doi: 10.4161/cc.21196. Epub 2012 Aug 1.

PMID:
22801546
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Aneuploidy facilitates oncogenic transformation via specific genetic alterations, including Twist2 upregulation.

Högnäs G, Hämälistö S, Rilla K, Laine JO, Vilkki V, Murumägi A, Edgren H, Kallioniemi O, Ivaska J.

Carcinogenesis. 2013 Sep;34(9):2000-9. doi: 10.1093/carcin/bgt171. Epub 2013 May 20.

PMID:
23689353
[PubMed - indexed for MEDLINE]
4.

Integrin trafficking regulated by Rab21 is necessary for cytokinesis.

Pellinen T, Tuomi S, Arjonen A, Wolf M, Edgren H, Meyer H, Grosse R, Kitzing T, Rantala JK, Kallioniemi O, Fässler R, Kallio M, Ivaska J.

Dev Cell. 2008 Sep;15(3):371-85. doi: 10.1016/j.devcel.2008.08.001.

PMID:
18804435
[PubMed - indexed for MEDLINE]
Free Article
5.

Competitive binding of Rab21 and p120RasGAP to integrins regulates receptor traffic and migration.

Mai A, Veltel S, Pellinen T, Padzik A, Coffey E, Marjomäki V, Ivaska J.

J Cell Biol. 2011 Jul 25;194(2):291-306. doi: 10.1083/jcb.201012126. Epub 2011 Jul 18.

PMID:
21768288
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins.

Pellinen T, Arjonen A, Vuoriluoto K, Kallio K, Fransen JA, Ivaska J.

J Cell Biol. 2006 Jun 5;173(5):767-80.

PMID:
16754960
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

MAD2DeltaC induces aneuploidy and promotes anchorage-independent growth in human prostate epithelial cells.

To-Ho KW, Cheung HW, Ling MT, Wong YC, Wang X.

Oncogene. 2008 Jan 10;27(3):347-57. Epub 2007 Jul 9.

PMID:
17621272
[PubMed - indexed for MEDLINE]
8.

Frequent overexpression of STK15/Aurora-A/BTAK and chromosomal instability in tumorigenic cell cultures derived from human ovarian cancer.

Hu W, Kavanagh JJ, Deaver M, Johnston DA, Freedman RS, Verschraegen CF, Sen S.

Oncol Res. 2005;15(1):49-57.

PMID:
15839305
[PubMed - indexed for MEDLINE]
9.

Targeting ILK and β4 integrin abrogates the invasive potential of ovarian cancer.

Choi YP, Kim BG, Gao MQ, Kang S, Cho NH.

Biochem Biophys Res Commun. 2012 Oct 26;427(3):642-8. doi: 10.1016/j.bbrc.2012.09.114. Epub 2012 Sep 28.

PMID:
23026047
[PubMed - indexed for MEDLINE]
10.

Mammary epithelial-specific expression of the integrin-linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice.

White DE, Cardiff RD, Dedhar S, Muller WJ.

Oncogene. 2001 Oct 25;20(48):7064-72.

PMID:
11704830
[PubMed - indexed for MEDLINE]
Free Article
11.

Spontaneous transformation of murine epithelial cells requires the early acquisition of specific chromosomal aneuploidies and genomic imbalances.

Padilla-Nash HM, Hathcock K, McNeil NE, Mack D, Hoeppner D, Ravin R, Knutsen T, Yonescu R, Wangsa D, Dorritie K, Barenboim L, Hu Y, Ried T.

Genes Chromosomes Cancer. 2012 Apr;51(4):353-74. doi: 10.1002/gcc.21921. Epub 2011 Dec 8.

PMID:
22161874
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

PRL-3 suppresses c-Fos and integrin α2 expression in ovarian cancer cells.

Liu H, Al-aidaroos AQ, Wang H, Guo K, Li J, Zhang HF, Zeng Q.

BMC Cancer. 2013 Feb 18;13:80. doi: 10.1186/1471-2407-13-80.

PMID:
23418787
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The role of alpha 6 beta 1 integrin and EGF in normal and malignant acinar morphogenesis of human prostatic epithelial cells.

Bello-DeOcampo D, Kleinman HK, Webber MM.

Mutat Res. 2001 Sep 1;480-481:209-17.

PMID:
11506815
[PubMed - indexed for MEDLINE]
14.

Macrophages facilitate coal tar pitch extract-induced tumorigenic transformation of human bronchial epithelial cells mediated by NF-κB.

Feng F, Wu Y, Zhang S, Liu Y, Qin L, Wu Y, Yan Z, Wu W.

PLoS One. 2012;7(12):e51690. doi: 10.1371/journal.pone.0051690. Epub 2012 Dec 5.

PMID:
23227270
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations.

Sato M, Larsen JE, Lee W, Sun H, Shames DS, Dalvi MP, Ramirez RD, Tang H, DiMaio JM, Gao B, Xie Y, Wistuba II, Gazdar AF, Shay JW, Minna JD.

Mol Cancer Res. 2013 Jun;11(6):638-50. doi: 10.1158/1541-7786.MCR-12-0634-T. Epub 2013 Feb 28.

PMID:
23449933
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model in vivo.

Mullany LK, Fan HY, Liu Z, White LD, Marshall A, Gunaratne P, Anderson ML, Creighton CJ, Xin L, Deavers M, Wong KK, Richards JS.

Oncogene. 2011 Aug 11;30(32):3522-36. doi: 10.1038/onc.2011.70. Epub 2011 Mar 21.

PMID:
21423204
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Spontaneous transformation of rat ovarian surface epithelial cells: association with cytogenetic changes and implications of repeated ovulation in the etiology of ovarian cancer.

Godwin AK, Testa JR, Handel LM, Liu Z, Vanderveer LA, Tracey PA, Hamilton TC.

J Natl Cancer Inst. 1992 Apr 15;84(8):592-601.

PMID:
1556770
[PubMed - indexed for MEDLINE]
18.

AFAP-110 is overexpressed in prostate cancer and contributes to tumorigenic growth by regulating focal contacts.

Zhang J, Park SI, Artime MC, Summy JM, Shah AN, Bomser JA, Dorfleutner A, Flynn DC, Gallick GE.

J Clin Invest. 2007 Oct;117(10):2962-73.

PMID:
17885682
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Loss of GATA6 leads to nuclear deformation and aneuploidy in ovarian cancer.

Capo-chichi CD, Cai KQ, Testa JR, Godwin AK, Xu XX.

Mol Cell Biol. 2009 Sep;29(17):4766-77. doi: 10.1128/MCB.00087-09. Epub 2009 Jul 6.

PMID:
19581290
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells.

Fujiwara T, Bandi M, Nitta M, Ivanova EV, Bronson RT, Pellman D.

Nature. 2005 Oct 13;437(7061):1043-7.

PMID:
16222300
[PubMed - indexed for MEDLINE]
Free Article

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