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Results: 1 to 20 of 91

1.

Aberrant epigenetic regulation of bromodomain BRD4 in human colon cancer.

Rodriguez RM, Huidobro C, Urdinguio RG, Mangas C, Soldevilla B, Domínguez G, Bonilla F, Fernandez AF, Fraga MF.

J Mol Med (Berl). 2012 May;90(5):587-95. doi: 10.1007/s00109-011-0837-0. Epub 2011 Nov 27.

PMID:
22120039
[PubMed - indexed for MEDLINE]
2.

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.

Zuber J, Shi J, Wang E, Rappaport AR, Herrmann H, Sison EA, Magoon D, Qi J, Blatt K, Wunderlich M, Taylor MJ, Johns C, Chicas A, Mulloy JC, Kogan SC, Brown P, Valent P, Bradner JE, Lowe SW, Vakoc CR.

Nature. 2011 Aug 3;478(7370):524-8. doi: 10.1038/nature10334.

PMID:
21814200
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Epigenetic inactivation of T-box transcription factor 5, a novel tumor suppressor gene, is associated with colon cancer.

Yu J, Ma X, Cheung KF, Li X, Tian L, Wang S, Wu CW, Wu WK, He M, Wang M, Ng SS, Sung JJ.

Oncogene. 2010 Dec 9;29(49):6464-74. doi: 10.1038/onc.2010.370. Epub 2010 Aug 30.

PMID:
20802524
[PubMed - indexed for MEDLINE]
4.

Epigenetic regulation of the human p53 gene promoter by the CTCF transcription factor in transformed cell lines.

Soto-Reyes E, Recillas-Targa F.

Oncogene. 2010 Apr 15;29(15):2217-27. doi: 10.1038/onc.2009.509. Epub 2010 Jan 25.

PMID:
20101205
[PubMed - indexed for MEDLINE]
5.

Frequent epigenetic inactivation of Wnt inhibitory factor-1 in human gastrointestinal cancers.

Taniguchi H, Yamamoto H, Hirata T, Miyamoto N, Oki M, Nosho K, Adachi Y, Endo T, Imai K, Shinomura Y.

Oncogene. 2005 Nov 24;24(53):7946-52.

PMID:
16007117
[PubMed - indexed for MEDLINE]
6.

Homeobox gene Rhox5 is regulated by epigenetic mechanisms in cancer and stem cells and promotes cancer growth.

Li Q, O'Malley ME, Bartlett DL, Guo ZS.

Mol Cancer. 2011 May 24;10:63. doi: 10.1186/1476-4598-10-63.

PMID:
21609483
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Epigenetic silencers and Notch collaborate to promote malignant tumours by Rb silencing.

Ferres-Marco D, Gutierrez-Garcia I, Vallejo DM, Bolivar J, Gutierrez-Aviño FJ, Dominguez M.

Nature. 2006 Jan 26;439(7075):430-6.

PMID:
16437107
[PubMed - indexed for MEDLINE]
8.

The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation.

Wu SY, Chiang CM.

J Biol Chem. 2007 May 4;282(18):13141-5. Epub 2007 Feb 28. Review.

PMID:
17329240
[PubMed - indexed for MEDLINE]
Free Article
9.

Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines.

Lopes EC, Valls E, Figueroa ME, Mazur A, Meng FG, Chiosis G, Laird PW, Schreiber-Agus N, Greally JM, Prokhortchouk E, Melnick A.

Cancer Res. 2008 Sep 15;68(18):7258-63. doi: 10.1158/0008-5472.CAN-08-0344.

PMID:
18794111
[PubMed - indexed for MEDLINE]
Free Article
10.

Re-expression of methylation-induced tumor suppressor gene silencing is associated with the state of histone modification in gastric cancer cell lines.

Meng CF, Zhu XJ, Peng G, Dai DQ.

World J Gastroenterol. 2007 Dec 14;13(46):6166-71.

PMID:
18069755
[PubMed - indexed for MEDLINE]
Free Article
11.

The bromodomain protein Brd4 stimulates G1 gene transcription and promotes progression to S phase.

Mochizuki K, Nishiyama A, Jang MK, Dey A, Ghosh A, Tamura T, Natsume H, Yao H, Ozato K.

J Biol Chem. 2008 Apr 4;283(14):9040-8. doi: 10.1074/jbc.M707603200. Epub 2008 Jan 27.

PMID:
18223296
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Regulation of aurora B expression by the bromodomain protein Brd4.

You J, Li Q, Wu C, Kim J, Ottinger M, Howley PM.

Mol Cell Biol. 2009 Sep;29(18):5094-103. doi: 10.1128/MCB.00299-09. Epub 2009 Jul 13.

PMID:
19596781
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Brd4 marks select genes on mitotic chromatin and directs postmitotic transcription.

Dey A, Nishiyama A, Karpova T, McNally J, Ozato K.

Mol Biol Cell. 2009 Dec;20(23):4899-909. doi: 10.1091/mbc.E09-05-0380. Epub 2009 Oct 7.

PMID:
19812244
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Histone acetylation and subcellular localization of chromosomal protein BRD4 during mouse oocyte meiosis and mitosis.

Nagashima T, Maruyama T, Furuya M, Kajitani T, Uchida H, Masuda H, Ono M, Arase T, Ozato K, Yoshimura Y.

Mol Hum Reprod. 2007 Mar;13(3):141-8. Epub 2007 Jan 31.

PMID:
17267518
[PubMed - indexed for MEDLINE]
Free Article
15.

FOXC1, a target of polycomb, inhibits metastasis of breast cancer cells.

Du J, Li L, Ou Z, Kong C, Zhang Y, Dong Z, Zhu S, Jiang H, Shao Z, Huang B, Lu J.

Breast Cancer Res Treat. 2012 Jan;131(1):65-73. doi: 10.1007/s10549-011-1396-3. Epub 2011 Apr 5.

PMID:
21465172
[PubMed - indexed for MEDLINE]
16.

Affinity map of bromodomain protein 4 (BRD4) interactions with the histone H4 tail and the small molecule inhibitor JQ1.

Jung M, Philpott M, Müller S, Schulze J, Badock V, Eberspächer U, Moosmayer D, Bader B, Schmees N, Fernández-Montalván A, Haendler B.

J Biol Chem. 2014 Mar 28;289(13):9304-19. doi: 10.1074/jbc.M113.523019. Epub 2014 Feb 4.

PMID:
24497639
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Dysregulated expression of stem cell factor Bmi1 in precancerous lesions of the gastrointestinal tract.

Tateishi K, Ohta M, Kanai F, Guleng B, Tanaka Y, Asaoka Y, Tada M, Seto M, Jazag A, Lianjie L, Okamoto M, Isayama H, Tada M, Yoshida H, Kawabe T, Omata M.

Clin Cancer Res. 2006 Dec 1;12(23):6960-6.

PMID:
17145814
[PubMed - indexed for MEDLINE]
Free Article
18.

Frequent epigenetic inactivation of Myocardin in human nasopharyngeal carcinoma.

Chen F, Mo Y, Ding H, Xiao X, Wang SY, Huang G, Zhang Z, Wang SZ.

Head Neck. 2011 Jan;33(1):54-9. doi: 10.1002/hed.21396.

PMID:
20848417
[PubMed - indexed for MEDLINE]
19.

Silencing of imprinted CDKN1C gene expression is associated with loss of CpG and histone H3 lysine 9 methylation at DMR-LIT1 in esophageal cancer.

Soejima H, Nakagawachi T, Zhao W, Higashimoto K, Urano T, Matsukura S, Kitajima Y, Takeuchi M, Nakayama M, Oshimura M, Miyazaki K, Joh K, Mukai T.

Oncogene. 2004 May 27;23(25):4380-8.

PMID:
15007390
[PubMed - indexed for MEDLINE]
20.

pRb2/p130-E2F4/5-HDAC1-SUV39H1-p300 and pRb2/p130-E2F4/5-HDAC1-SUV39H1-DNMT1 multimolecular complexes mediate the transcription of estrogen receptor-alpha in breast cancer.

Macaluso M, Cinti C, Russo G, Russo A, Giordano A.

Oncogene. 2003 Jun 5;22(23):3511-7.

PMID:
12789259
[PubMed - indexed for MEDLINE]

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