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Results: 1 to 20 of 181

1.

The NLRP3 inflammasome is active but not essential in endotoxin-induced uveitis.

Rosenzweig HL, Woods A, Clowers JS, Planck SR, Rosenbaum JT.

Inflamm Res. 2012 Mar;61(3):225-31. doi: 10.1007/s00011-011-0404-8. Epub 2011 Nov 26.

PMID:
22119862
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury.

Shigeoka AA, Mueller JL, Kambo A, Mathison JC, King AJ, Hall WF, Correia Jda S, Ulevitch RJ, Hoffman HM, McKay DB.

J Immunol. 2010 Nov 15;185(10):6277-85. doi: 10.4049/jimmunol.1002330. Epub 2010 Oct 20. Erratum in: J Immunol. 2011 Feb 1;186(3):1880.

PMID:
20962258
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production.

Hu Y, Mao K, Zeng Y, Chen S, Tao Z, Yang C, Sun S, Wu X, Meng G, Sun B.

J Immunol. 2010 Dec 15;185(12):7699-705. doi: 10.4049/jimmunol.1001099. Epub 2010 Nov 3.

PMID:
21048113
[PubMed - indexed for MEDLINE]
Free Article
4.

The NLRP3/ASC/Caspase-1 axis regulates IL-1β processing in neutrophils.

Mankan AK, Dau T, Jenne D, Hornung V.

Eur J Immunol. 2012 Mar;42(3):710-5. doi: 10.1002/eji.201141921. Epub 2012 Jan 19.

PMID:
22213227
[PubMed - indexed for MEDLINE]
5.

The inflammasome sensor, NLRP3, regulates CNS inflammation and demyelination via caspase-1 and interleukin-18.

Jha S, Srivastava SY, Brickey WJ, Iocca H, Toews A, Morrison JP, Chen VS, Gris D, Matsushima GK, Ting JP.

J Neurosci. 2010 Nov 24;30(47):15811-20. doi: 10.1523/JNEUROSCI.4088-10.2010.

PMID:
21106820
[PubMed - indexed for MEDLINE]
Free Article
6.

Apoptosis-associated speck-like protein containing a caspase recruitment domain inflammasomes mediate IL-1β response and host resistance to Trypanosoma cruzi infection.

Silva GK, Costa RS, Silveira TN, Caetano BC, Horta CV, Gutierrez FR, Guedes PM, Andrade WA, De Niz M, Gazzinelli RT, Zamboni DS, Silva JS.

J Immunol. 2013 Sep 15;191(6):3373-83. doi: 10.4049/jimmunol.1203293. Epub 2013 Aug 21.

PMID:
23966627
[PubMed - indexed for MEDLINE]
7.

Stress-induced cartilage degradation does not depend on the NLRP3 inflammasome in human osteoarthritis and mouse models.

Bougault C, Gosset M, Houard X, Salvat C, Godmann L, Pap T, Jacques C, Berenbaum F.

Arthritis Rheum. 2012 Dec;64(12):3972-81. doi: 10.1002/art.34678.

PMID:
22933232
[PubMed - indexed for MEDLINE]
Free Article
8.

NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B(4) in a murine model of gout.

Amaral FA, Costa VV, Tavares LD, Sachs D, Coelho FM, Fagundes CT, Soriani FM, Silveira TN, Cunha LD, Zamboni DS, Quesniaux V, Peres RS, Cunha TM, Cunha FQ, Ryffel B, Souza DG, Teixeira MM.

Arthritis Rheum. 2012 Feb;64(2):474-84. doi: 10.1002/art.33355.

PMID:
21952942
[PubMed - indexed for MEDLINE]
Free Article
9.

Critical role for the NLRP3 inflammasome during acute lung injury.

Grailer JJ, Canning BA, Kalbitz M, Haggadone MD, Dhond RM, Andjelkovic AV, Zetoune FS, Ward PA.

J Immunol. 2014 Jun 15;192(12):5974-83. doi: 10.4049/jimmunol.1400368. Epub 2014 May 2.

PMID:
24795455
[PubMed - indexed for MEDLINE]
10.

Activation of the NLRP3 inflammasome by group B streptococci.

Costa A, Gupta R, Signorino G, Malara A, Cardile F, Biondo C, Midiri A, Galbo R, Trieu-Cuot P, Papasergi S, Teti G, Henneke P, Mancuso G, Golenbock DT, Beninati C.

J Immunol. 2012 Feb 15;188(4):1953-60. doi: 10.4049/jimmunol.1102543. Epub 2012 Jan 16.

PMID:
22250086
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Alcohol-induced IL-1β in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation.

Lippai D, Bala S, Petrasek J, Csak T, Levin I, Kurt-Jones EA, Szabo G.

J Leukoc Biol. 2013 Jul;94(1):171-82. doi: 10.1189/jlb.1212659. Epub 2013 Apr 26.

PMID:
23625200
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Inflammasome-independent role of the apoptosis-associated speck-like protein containing CARD (ASC) in the adjuvant effect of MF59.

Ellebedy AH, Lupfer C, Ghoneim HE, DeBeauchamp J, Kanneganti TD, Webby RJ.

Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2927-32. doi: 10.1073/pnas.1012455108. Epub 2011 Jan 26. Erratum in: Proc Natl Acad Sci U S A. 2013 Mar 12;110(11):4429.

PMID:
21270336
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Varicella-zoster virus infection triggers formation of an interleukin-1β (IL-1β)-processing inflammasome complex.

Nour AM, Reichelt M, Ku CC, Ho MY, Heineman TC, Arvin AM.

J Biol Chem. 2011 May 20;286(20):17921-33. doi: 10.1074/jbc.M110.210575. Epub 2011 Mar 8.

PMID:
21385879
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

MicroRNA-133a-1 regulates inflammasome activation through uncoupling protein-2.

Bandyopadhyay S, Lane T, Venugopal R, Parthasarathy PT, Cho Y, Galam L, Lockey R, Kolliputi N.

Biochem Biophys Res Commun. 2013 Sep 27;439(3):407-12. doi: 10.1016/j.bbrc.2013.08.056. Epub 2013 Aug 27.

PMID:
23988448
[PubMed - indexed for MEDLINE]
15.

A role for uric acid and the Nalp3 inflammasome in antiphospholipid antibody-induced IL-1β production by human first trimester trophoblast.

Mulla MJ, Salmon JE, Chamley LW, Brosens JJ, Boeras CM, Kavathas PB, Abrahams VM.

PLoS One. 2013 Jun 6;8(6):e65237. doi: 10.1371/journal.pone.0065237. Print 2013.

PMID:
23762324
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome.

Duncan JA, Gao X, Huang MT, O'Connor BP, Thomas CE, Willingham SB, Bergstralh DT, Jarvis GA, Sparling PF, Ting JP.

J Immunol. 2009 May 15;182(10):6460-9. doi: 10.4049/jimmunol.0802696.

PMID:
19414800
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Follistatin-like protein 1 enhances NLRP3 inflammasome-mediated IL-1β secretion from monocytes and macrophages.

Chaly Y, Fu Y, Marinov A, Hostager B, Yan W, Campfield B, Kellum JA, Bushnell D, Wang Y, Vockley J, Hirsch R.

Eur J Immunol. 2014 May;44(5):1467-79. doi: 10.1002/eji.201344063. Epub 2014 Feb 20.

PMID:
24470197
[PubMed - indexed for MEDLINE]
18.

The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury.

Sandanger Ø, Ranheim T, Vinge LE, Bliksøen M, Alfsnes K, Finsen AV, Dahl CP, Askevold ET, Florholmen G, Christensen G, Fitzgerald KA, Lien E, Valen G, Espevik T, Aukrust P, Yndestad A.

Cardiovasc Res. 2013 Jul 1;99(1):164-74. doi: 10.1093/cvr/cvt091. Epub 2013 Apr 10.

PMID:
23580606
[PubMed - indexed for MEDLINE]
Free Article
19.

Histones trigger sterile inflammation by activating the NLRP3 inflammasome.

Allam R, Darisipudi MN, Tschopp J, Anders HJ.

Eur J Immunol. 2013 Dec;43(12):3336-42. doi: 10.1002/eji.201243224. Epub 2013 Sep 6.

PMID:
23964013
[PubMed - indexed for MEDLINE]
20.

Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection.

Fang R, Tsuchiya K, Kawamura I, Shen Y, Hara H, Sakai S, Yamamoto T, Fernandes-Alnemri T, Yang R, Hernandez-Cuellar E, Dewamitta SR, Xu Y, Qu H, Alnemri ES, Mitsuyama M.

J Immunol. 2011 Nov 1;187(9):4890-9. doi: 10.4049/jimmunol.1100381. Epub 2011 Sep 28.

PMID:
21957143
[PubMed - indexed for MEDLINE]
Free PMC Article

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