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Results: 1 to 20 of 123

1.

The NLRP3 inflammasome is active but not essential in endotoxin-induced uveitis.

Rosenzweig HL, Woods A, Clowers JS, Planck SR, Rosenbaum JT.

Inflamm Res. 2012 Mar;61(3):225-31. doi: 10.1007/s00011-011-0404-8. Epub 2011 Nov 26.

PMID:
22119862
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response.

Baroja-Mazo A, Martín-Sánchez F, Gomez AI, Martínez CM, Amores-Iniesta J, Compan V, Barberà-Cremades M, Yagüe J, Ruiz-Ortiz E, Antón J, Buján S, Couillin I, Brough D, Arostegui JI, Pelegrín P.

Nat Immunol. 2014 Aug;15(8):738-48. doi: 10.1038/ni.2919. Epub 2014 Jun 22.

PMID:
24952504
[PubMed - indexed for MEDLINE]
3.

The NLRP3/ASC/Caspase-1 axis regulates IL-1β processing in neutrophils.

Mankan AK, Dau T, Jenne D, Hornung V.

Eur J Immunol. 2012 Mar;42(3):710-5. doi: 10.1002/eji.201141921. Epub 2012 Jan 19.

PMID:
22213227
[PubMed - indexed for MEDLINE]
4.

An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury.

Shigeoka AA, Mueller JL, Kambo A, Mathison JC, King AJ, Hall WF, Correia Jda S, Ulevitch RJ, Hoffman HM, McKay DB.

J Immunol. 2010 Nov 15;185(10):6277-85. doi: 10.4049/jimmunol.1002330. Epub 2010 Oct 20. Erratum in: J Immunol. 2011 Feb 1;186(3):1880.

PMID:
20962258
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Critical role for the NLRP3 inflammasome during acute lung injury.

Grailer JJ, Canning BA, Kalbitz M, Haggadone MD, Dhond RM, Andjelkovic AV, Zetoune FS, Ward PA.

J Immunol. 2014 Jun 15;192(12):5974-83. doi: 10.4049/jimmunol.1400368. Epub 2014 May 2.

PMID:
24795455
[PubMed - indexed for MEDLINE]
6.

Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasome.

Kailasan Vanaja S, Rathinam VA, Atianand MK, Kalantari P, Skehan B, Fitzgerald KA, Leong JM.

Proc Natl Acad Sci U S A. 2014 May 27;111(21):7765-70. doi: 10.1073/pnas.1400075111. Epub 2014 May 14.

PMID:
24828532
[PubMed - indexed for MEDLINE]
7.

Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production.

Hu Y, Mao K, Zeng Y, Chen S, Tao Z, Yang C, Sun S, Wu X, Meng G, Sun B.

J Immunol. 2010 Dec 15;185(12):7699-705. doi: 10.4049/jimmunol.1001099. Epub 2010 Nov 3.

PMID:
21048113
[PubMed - indexed for MEDLINE]
Free Article
8.

Reactive oxygen species activated NLRP3 inflammasomes prime environment-induced murine dry eye.

Zheng Q, Ren Y, Reinach PS, She Y, Xiao B, Hua S, Qu J, Chen W.

Exp Eye Res. 2014 Aug;125:1-8. doi: 10.1016/j.exer.2014.05.001. Epub 2014 May 14.

PMID:
24836981
[PubMed - indexed for MEDLINE]
9.

Alcohol-induced IL-1β in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation.

Lippai D, Bala S, Petrasek J, Csak T, Levin I, Kurt-Jones EA, Szabo G.

J Leukoc Biol. 2013 Jul;94(1):171-82. doi: 10.1189/jlb.1212659. Epub 2013 Apr 26.

PMID:
23625200
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Apoptosis-associated speck-like protein containing a caspase recruitment domain inflammasomes mediate IL-1β response and host resistance to Trypanosoma cruzi infection.

Silva GK, Costa RS, Silveira TN, Caetano BC, Horta CV, Gutierrez FR, Guedes PM, Andrade WA, De Niz M, Gazzinelli RT, Zamboni DS, Silva JS.

J Immunol. 2013 Sep 15;191(6):3373-83. doi: 10.4049/jimmunol.1203293. Epub 2013 Aug 21.

PMID:
23966627
[PubMed - indexed for MEDLINE]
Free Article
11.

Follistatin-like protein 1 enhances NLRP3 inflammasome-mediated IL-1β secretion from monocytes and macrophages.

Chaly Y, Fu Y, Marinov A, Hostager B, Yan W, Campfield B, Kellum JA, Bushnell D, Wang Y, Vockley J, Hirsch R.

Eur J Immunol. 2014 May;44(5):1467-79. doi: 10.1002/eji.201344063. Epub 2014 Feb 20.

PMID:
24470197
[PubMed - indexed for MEDLINE]
12.

Aloe vera downregulates LPS-induced inflammatory cytokine production and expression of NLRP3 inflammasome in human macrophages.

Budai MM, Varga A, Milesz S, Tőzsér J, Benkő S.

Mol Immunol. 2013 Dec;56(4):471-9. doi: 10.1016/j.molimm.2013.05.005. Epub 2013 Aug 1.

PMID:
23911403
[PubMed - indexed for MEDLINE]
13.

Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome.

Duncan JA, Gao X, Huang MT, O'Connor BP, Thomas CE, Willingham SB, Bergstralh DT, Jarvis GA, Sparling PF, Ting JP.

J Immunol. 2009 May 15;182(10):6460-9. doi: 10.4049/jimmunol.0802696.

PMID:
19414800
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

A Yersinia effector with enhanced inhibitory activity on the NF-κB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages.

Zheng Y, Lilo S, Brodsky IE, Zhang Y, Medzhitov R, Marcu KB, Bliska JB.

PLoS Pathog. 2011 Apr;7(4):e1002026. doi: 10.1371/journal.ppat.1002026. Epub 2011 Apr 21.

PMID:
21533069
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Histones trigger sterile inflammation by activating the NLRP3 inflammasome.

Allam R, Darisipudi MN, Tschopp J, Anders HJ.

Eur J Immunol. 2013 Dec;43(12):3336-42. doi: 10.1002/eji.201243224. Epub 2013 Sep 6.

PMID:
23964013
[PubMed - indexed for MEDLINE]
16.

A role for uric acid and the Nalp3 inflammasome in antiphospholipid antibody-induced IL-1β production by human first trimester trophoblast.

Mulla MJ, Salmon JE, Chamley LW, Brosens JJ, Boeras CM, Kavathas PB, Abrahams VM.

PLoS One. 2013 Jun 6;8(6):e65237. doi: 10.1371/journal.pone.0065237. Print 2013.

PMID:
23762324
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

NLRP3 inflammasome knockout mice are protected against ischemic but not cisplatin-induced acute kidney injury.

Kim HJ, Lee DW, Ravichandran K, O Keys D, Akcay A, Nguyen Q, He Z, Jani A, Ljubanovic D, Edelstein CL.

J Pharmacol Exp Ther. 2013 Sep;346(3):465-72. doi: 10.1124/jpet.113.205732. Epub 2013 Jul 5.

PMID:
23833276
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The inflammasome sensor, NLRP3, regulates CNS inflammation and demyelination via caspase-1 and interleukin-18.

Jha S, Srivastava SY, Brickey WJ, Iocca H, Toews A, Morrison JP, Chen VS, Gris D, Matsushima GK, Ting JP.

J Neurosci. 2010 Nov 24;30(47):15811-20. doi: 10.1523/JNEUROSCI.4088-10.2010.

PMID:
21106820
[PubMed - indexed for MEDLINE]
Free Article
19.

MicroRNA-133a-1 regulates inflammasome activation through uncoupling protein-2.

Bandyopadhyay S, Lane T, Venugopal R, Parthasarathy PT, Cho Y, Galam L, Lockey R, Kolliputi N.

Biochem Biophys Res Commun. 2013 Sep 27;439(3):407-12. doi: 10.1016/j.bbrc.2013.08.056. Epub 2013 Aug 27.

PMID:
23988448
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii.

Gorfu G, Cirelli KM, Melo MB, Mayer-Barber K, Crown D, Koller BH, Masters S, Sher A, Leppla SH, Moayeri M, Saeij JP, Grigg ME.

MBio. 2014 Feb 18;5(1). pii: e01117-13. doi: 10.1128/mBio.01117-13.

PMID:
24549849
[PubMed - indexed for MEDLINE]
Free PMC Article

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