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Results: 1 to 20 of 229

1.

Musashi expression in β-cells coordinates insulin expression, apoptosis and proliferation in response to endoplasmic reticulum stress in diabetes.

Szabat M, Kalynyak TB, Lim GE, Chu KY, Yang YH, Asadi A, Gage BK, Ao Z, Warnock GL, Piret JM, Kieffer TJ, Johnson JD.

Cell Death Dis. 2011 Nov 24;2:e232. doi: 10.1038/cddis.2011.119.

PMID:
22113197
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Pdx1 and Ngn3 overexpression enhances pancreatic differentiation of mouse ES cell-derived endoderm population.

Kubo A, Stull R, Takeuchi M, Bonham K, Gouon-Evans V, Sho M, Iwano M, Saito Y, Keller G, Snodgrass R.

PLoS One. 2011;6(9):e24058. doi: 10.1371/journal.pone.0024058. Epub 2011 Sep 13.

PMID:
21931641
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The adult stem cell marker Musashi-1 modulates endometrial carcinoma cell cycle progression and apoptosis via Notch-1 and p21WAF1/CIP1.

Götte M, Greve B, Kelsch R, Müller-Uthoff H, Weiss K, Kharabi Masouleh B, Sibrowski W, Kiesel L, Buchweitz O.

Int J Cancer. 2011 Oct 15;129(8):2042-9. doi: 10.1002/ijc.25856. Epub 2011 Mar 4.

PMID:
21165952
[PubMed - indexed for MEDLINE]
4.

Redifferentiation of expanded human pancreatic β-cell-derived cells by inhibition of the NOTCH pathway.

Bar Y, Russ HA, Sintov E, Anker-Kitai L, Knoller S, Efrat S.

J Biol Chem. 2012 May 18;287(21):17269-80. doi: 10.1074/jbc.M111.319152. Epub 2012 Mar 28.

PMID:
22457355
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes.

Laybutt DR, Preston AM, Akerfeldt MC, Kench JG, Busch AK, Biankin AV, Biden TJ.

Diabetologia. 2007 Apr;50(4):752-63. Epub 2007 Feb 1.

PMID:
17268797
[PubMed - indexed for MEDLINE]
6.

Higher expression patterns of the intestinal stem cell markers Musashi-1 and hairy and enhancer of split 1 and their correspondence with proliferation patterns in the mouse jejunum.

Yu T, Chen QK, Gong Y, Xia ZS, Royal CR, Huang KH.

Med Sci Monit. 2010 Feb;16(2):BR68-74.

PMID:
20110912
[PubMed - indexed for MEDLINE]
7.

HES-1 is involved in adaptation of adult human beta-cells to proliferation in vitro.

Bar Y, Russ HA, Knoller S, Ouziel-Yahalom L, Efrat S.

Diabetes. 2008 Sep;57(9):2413-20. doi: 10.2337/db07-1323. Epub 2008 Jul 3.

PMID:
18599525
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Anks4b, a novel target of HNF4α protein, interacts with GRP78 protein and regulates endoplasmic reticulum stress-induced apoptosis in pancreatic β-cells.

Sato Y, Hatta M, Karim MF, Sawa T, Wei FY, Sato S, Magnuson MA, Gonzalez FJ, Tomizawa K, Akaike T, Yoshizawa T, Yamagata K.

J Biol Chem. 2012 Jun 29;287(27):23236-45. doi: 10.1074/jbc.M112.368779. Epub 2012 May 15.

PMID:
22589549
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB.

Cunha DA, Ladrière L, Ortis F, Igoillo-Esteve M, Gurzov EN, Lupi R, Marchetti P, Eizirik DL, Cnop M.

Diabetes. 2009 Dec;58(12):2851-62. doi: 10.2337/db09-0685. Epub 2009 Aug 31.

PMID:
19720788
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress.

Sachdeva MM, Claiborn KC, Khoo C, Yang J, Groff DN, Mirmira RG, Stoffers DA.

Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19090-5. doi: 10.1073/pnas.0904849106. Epub 2009 Oct 23.

PMID:
19855005
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes.

Huang CJ, Lin CY, Haataja L, Gurlo T, Butler AE, Rizza RA, Butler PC.

Diabetes. 2007 Aug;56(8):2016-27. Epub 2007 May 2.

PMID:
17475933
[PubMed - indexed for MEDLINE]
Free Article
12.

Numb modulates intestinal epithelial cells toward goblet cell phenotype by inhibiting the Notch signaling pathway.

Yang Y, Zhu R, Bai J, Zhang X, Tian Y, Li X, Peng Z, He Y, Chen L, Ji Q, Chen W, Fang D, Wang R.

Exp Cell Res. 2011 Jul 1;317(11):1640-8. doi: 10.1016/j.yexcr.2011.04.008. Epub 2011 Apr 30.

PMID:
21557937
[PubMed - indexed for MEDLINE]
13.

Notch-HES1 signaling axis controls hemato-endothelial fate decisions of human embryonic and induced pluripotent stem cells.

Lee JB, Werbowetski-Ogilvie TE, Lee JH, McIntyre BA, Schnerch A, Hong SH, Park IH, Daley GQ, Bernstein ID, Bhatia M.

Blood. 2013 Aug 15;122(7):1162-73. doi: 10.1182/blood-2012-12-471649. Epub 2013 Jun 3.

PMID:
23733337
[PubMed - indexed for MEDLINE]
Free Article
14.

Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis.

Riggs AC, Bernal-Mizrachi E, Ohsugi M, Wasson J, Fatrai S, Welling C, Murray J, Schmidt RE, Herrera PL, Permutt MA.

Diabetologia. 2005 Nov;48(11):2313-21. Epub 2005 Oct 8.

PMID:
16215705
[PubMed - indexed for MEDLINE]
15.

Vildagliptin preserves the mass and function of pancreatic β cells via the developmental regulation and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes.

Hamamoto S, Kanda Y, Shimoda M, Tatsumi F, Kohara K, Tawaramoto K, Hashiramoto M, Kaku K.

Diabetes Obes Metab. 2013 Feb;15(2):153-63. doi: 10.1111/dom.12005. Epub 2012 Sep 25.

PMID:
22950702
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Impact of endoplasmic reticulum stress pathway on pancreatic beta-cells and diabetes mellitus.

Araki E, Oyadomari S, Mori M.

Exp Biol Med (Maywood). 2003 Nov;228(10):1213-7. Review.

PMID:
14610263
[PubMed - indexed for MEDLINE]
17.

Modulation of palmitate-induced endoplasmic reticulum stress and apoptosis in pancreatic β-cells by stearoyl-CoA desaturase and Elovl6.

Green CD, Olson LK.

Am J Physiol Endocrinol Metab. 2011 Apr;300(4):E640-9. doi: 10.1152/ajpendo.00544.2010. Epub 2011 Jan 25.

PMID:
21266672
[PubMed - indexed for MEDLINE]
Free Article
18.

Mitogen-inducible gene 6 triggers apoptosis and exacerbates ER stress-induced β-cell death.

Chen YC, Colvin ES, Maier BF, Mirmira RG, Fueger PT.

Mol Endocrinol. 2013 Jan;27(1):162-71. doi: 10.1210/me.2012-1174. Epub 2012 Nov 30.

PMID:
23204325
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Generation of functional insulin-producing cells from mouse embryonic stem cells through 804G cell-derived extracellular matrix and protein transduction of transcription factors.

Kaitsuka T, Noguchi H, Shiraki N, Kubo T, Wei FY, Hakim F, Kume S, Tomizawa K.

Stem Cells Transl Med. 2014 Jan;3(1):114-27. doi: 10.5966/sctm.2013-0075. Epub 2013 Nov 29.

PMID:
24292793
[PubMed - indexed for MEDLINE]
20.

The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.

Marchetti P, Bugliani M, Lupi R, Marselli L, Masini M, Boggi U, Filipponi F, Weir GC, Eizirik DL, Cnop M.

Diabetologia. 2007 Dec;50(12):2486-94. Epub 2007 Sep 30.

PMID:
17906960
[PubMed - indexed for MEDLINE]

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