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Items: 1 to 20 of 356

1.

Endoplasmic reticulum-tethered transcription factor cAMP responsive element-binding protein, hepatocyte specific, regulates hepatic lipogenesis, fatty acid oxidation, and lipolysis upon metabolic stress in mice.

Zhang C, Wang G, Zheng Z, Maddipati KR, Zhang X, Dyson G, Williams P, Duncan SA, Kaufman RJ, Zhang K.

Hepatology. 2012 Apr;55(4):1070-82. doi: 10.1002/hep.24783. Epub 2012 Feb 9.

2.

Liver-enriched transcription factor CREBH interacts with peroxisome proliferator-activated receptor α to regulate metabolic hormone FGF21.

Kim H, Mendez R, Zheng Z, Chang L, Cai J, Zhang R, Zhang K.

Endocrinology. 2014 Mar;155(3):769-82. doi: 10.1210/en.2013-1490. Epub 2014 Jan 1.

3.

cAMP response element binding protein H mediates fenofibrate-induced suppression of hepatic lipogenesis.

Min AK, Jeong JY, Go Y, Choi YK, Kim YD, Lee IK, Park KG.

Diabetologia. 2013 Feb;56(2):412-22. doi: 10.1007/s00125-012-2771-2. Epub 2012 Nov 13.

PMID:
23150180
4.

Absence of adipose triglyceride lipase protects from hepatic endoplasmic reticulum stress in mice.

Fuchs CD, Claudel T, Kumari P, Haemmerle G, Pollheimer MJ, Stojakovic T, Scharnagl H, Halilbasic E, Gumhold J, Silbert D, Koefeler H, Trauner M.

Hepatology. 2012 Jul;56(1):270-80. doi: 10.1002/hep.25601. Epub 2012 May 29.

PMID:
22271167
5.

Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H.

Luebke-Wheeler J, Zhang K, Battle M, Si-Tayeb K, Garrison W, Chhinder S, Li J, Kaufman RJ, Duncan SA.

Hepatology. 2008 Oct;48(4):1242-50. doi: 10.1002/hep.22439.

6.

Cannabinoid receptor type 1 (CB1R) signaling regulates hepatic gluconeogenesis via induction of endoplasmic reticulum-bound transcription factor cAMP-responsive element-binding protein H (CREBH) in primary hepatocytes.

Chanda D, Kim DK, Li T, Kim YH, Koo SH, Lee CH, Chiang JY, Choi HS.

J Biol Chem. 2011 Aug 12;286(32):27971-9. doi: 10.1074/jbc.M111.224352. Epub 2011 Jun 21.

7.

Accumulation of endoplasmic reticulum stress and lipogenesis in the liver through generational effects of high fat diets.

Li J, Huang J, Li JS, Chen H, Huang K, Zheng L.

J Hepatol. 2012 Apr;56(4):900-7. doi: 10.1016/j.jhep.2011.10.018. Epub 2011 Dec 13.

PMID:
22173165
8.

Orphan nuclear receptor Errγ induces C-reactive protein gene expression through induction of ER-bound Bzip transmembrane transcription factor CREBH.

Misra J, Chanda D, Kim DK, Cho SR, Koo SH, Lee CH, Back SH, Choi HS.

PLoS One. 2014 Jan 22;9(1):e86342. doi: 10.1371/journal.pone.0086342. eCollection 2014. Erratum in: PLoS One. 2015;10(5):e0125536.

9.

Activation of peroxisome proliferator-activated receptor alpha by dietary fish oil attenuates steatosis, but does not prevent experimental steatohepatitis because of hepatic lipoperoxide accumulation.

Larter CZ, Yeh MM, Cheng J, Williams J, Brown S, dela Pena A, Bell-Anderson KS, Farrell GC.

J Gastroenterol Hepatol. 2008 Feb;23(2):267-75. Epub 2007 Sep 12.

PMID:
17868330
10.

Hepatic steatosis, inflammation, and ER stress in mice maintained long term on a very low-carbohydrate ketogenic diet.

Garbow JR, Doherty JM, Schugar RC, Travers S, Weber ML, Wentz AE, Ezenwajiaku N, Cotter DG, Brunt EM, Crawford PA.

Am J Physiol Gastrointest Liver Physiol. 2011 Jun;300(6):G956-67. doi: 10.1152/ajpgi.00539.2010. Epub 2011 Mar 31.

11.

Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids.

Jaeger D, Schoiswohl G, Hofer P, Schreiber R, Schweiger M, Eichmann TO, Pollak NM, Poecher N, Grabner GF, Zierler KA, Eder S, Kolb D, Radner FP, Preiss-Landl K, Lass A, Zechner R, Kershaw EE, Haemmerle G.

J Hepatol. 2015 Aug;63(2):437-45. doi: 10.1016/j.jhep.2015.02.035. Epub 2015 Feb 27.

12.

Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response.

Zhang K, Shen X, Wu J, Sakaki K, Saunders T, Rutkowski DT, Back SH, Kaufman RJ.

Cell. 2006 Feb 10;124(3):587-99.

13.

Pharmacologic ER stress induces non-alcoholic steatohepatitis in an animal model.

Lee JS, Zheng Z, Mendez R, Ha SW, Xie Y, Zhang K.

Toxicol Lett. 2012 May 20;211(1):29-38. doi: 10.1016/j.toxlet.2012.02.017. Epub 2012 Mar 5.

14.

Identification and characterization of cyclic AMP response element-binding protein H response element in the human apolipoprotein A5 gene promoter.

Song KH, Park AY, Kim JE, Ma JY.

Biomed Res Int. 2013;2013:892491. doi: 10.1155/2013/892491. Epub 2013 Jul 17.

15.

Activation of cannabinoid receptor type 1 (Cb1r) disrupts hepatic insulin receptor signaling via cyclic AMP-response element-binding protein H (Crebh)-mediated induction of Lipin1 gene.

Chanda D, Kim YH, Kim DK, Lee MW, Lee SY, Park TS, Koo SH, Lee CH, Choi HS.

J Biol Chem. 2012 Nov 2;287(45):38041-9. doi: 10.1074/jbc.M112.377978. Epub 2012 Sep 18.

16.

CREBH Couples Circadian Clock with Hepatic Lipid Metabolism.

Zheng Z, Kim H, Qiu Y, Chen X, Mendez R, Dandekar A, Zhang X, Zhang C, Liu AC, Yin L, Lin JD, Walker PD, Kapatos G, Zhang K.

Diabetes. 2016 Aug 9. pii: db160298. [Epub ahead of print]

PMID:
27507854
17.

Transcriptional activation of Fsp27 by the liver-enriched transcription factor CREBH promotes lipid droplet growth and hepatic steatosis.

Xu X, Park JG, So JS, Lee AH.

Hepatology. 2015 Mar;61(3):857-69. doi: 10.1002/hep.27371. Epub 2015 Jan 28.

18.

Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance.

Ren LP, Chan SM, Zeng XY, Laybutt DR, Iseli TJ, Sun RQ, Kraegen EW, Cooney GJ, Turner N, Ye JM.

PLoS One. 2012;7(2):e30816. doi: 10.1371/journal.pone.0030816. Epub 2012 Feb 15.

19.

CCAAT/enhancing binding protein beta deletion in mice attenuates inflammation, endoplasmic reticulum stress, and lipid accumulation in diet-induced nonalcoholic steatohepatitis.

Rahman SM, Schroeder-Gloeckler JM, Janssen RC, Jiang H, Qadri I, Maclean KN, Friedman JE.

Hepatology. 2007 May;45(5):1108-17.

PMID:
17464987
20.

Altered expression of transcription factors and genes regulating lipogenesis in liver and adipose tissue of mice with high fat diet-induced obesity and nonalcoholic fatty liver disease.

Morgan K, Uyuni A, Nandgiri G, Mao L, Castaneda L, Kathirvel E, French SW, Morgan TR.

Eur J Gastroenterol Hepatol. 2008 Sep;20(9):843-54. doi: 10.1097/MEG.0b013e3282f9b203.

PMID:
18794597
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