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Results: 1 to 20 of 327

1.

Accumulation of p62 in degenerated spinal cord under chronic mechanical compression: functional analysis of p62 and autophagy in hypoxic neuronal cells.

Tanabe F, Yone K, Kawabata N, Sakakima H, Matsuda F, Ishidou Y, Maeda S, Abematsu M, Komiya S, Setoguchi T.

Autophagy. 2011 Dec;7(12):1462-71.

PMID:
22082874
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Tumor necrosis factor-alpha and its receptors contribute to apoptosis of oligodendrocytes in the spinal cord of spinal hyperostotic mouse (twy/twy) sustaining chronic mechanical compression.

Inukai T, Uchida K, Nakajima H, Yayama T, Kobayashi S, Mwaka ES, Guerrero AR, Baba H.

Spine (Phila Pa 1976). 2009 Dec 15;34(26):2848-57. doi: 10.1097/BRS.0b013e3181b0d078.

PMID:
19949368
[PubMed - indexed for MEDLINE]
3.

Induction of autophagy and autophagic cell death in damaged neural tissue after acute spinal cord injury in mice.

Kanno H, Ozawa H, Sekiguchi A, Yamaya S, Itoi E.

Spine (Phila Pa 1976). 2011 Oct 15;36(22):E1427-34. doi: 10.1097/BRS.0b013e3182028c3a.

PMID:
21304420
[PubMed - indexed for MEDLINE]
4.

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death.

Bjørkøy G, Lamark T, Brech A, Outzen H, Perander M, Overvatn A, Stenmark H, Johansen T.

J Cell Biol. 2005 Nov 21;171(4):603-14. Epub 2005 Nov 14.

PMID:
16286508
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Regulation of neuronal autophagy in axon: implication of autophagy in axonal function and dysfunction/degeneration.

Yue Z.

Autophagy. 2007 Mar-Apr;3(2):139-41. Epub 2007 Mar 14.

PMID:
17204855
[PubMed - indexed for MEDLINE]
Free Article
6.

Expression of apoptosis signal-regulating kinase 1 in mouse spinal cord under chronic mechanical compression: possible involvement of the stress-activated mitogen-activated protein kinase pathways in spinal cord cell apoptosis.

Takenouchi T, Setoguchi T, Yone K, Komiya S.

Spine (Phila Pa 1976). 2008 Aug 15;33(18):1943-50. doi: 10.1097/BRS.0b013e3181822ed7.

PMID:
18708926
[PubMed - indexed for MEDLINE]
7.

The retrograde delivery of adenovirus vector carrying the gene for brain-derived neurotrophic factor protects neurons and oligodendrocytes from apoptosis in the chronically compressed spinal cord of twy/twy mice.

Uchida K, Nakajima H, Hirai T, Yayama T, Chen K, Guerrero AR, Johnson WE, Baba H.

Spine (Phila Pa 1976). 2012 Dec 15;37(26):2125-35. doi: 10.1097/BRS.0b013e3182600ef7.

PMID:
22648027
[PubMed - indexed for MEDLINE]
8.

Binding preference of p62 towards LC3-ll during dopaminergic neurotoxin-induced impairment of autophagic flux.

Lim J, Kim HW, Youdim MB, Rhyu IJ, Choe KM, Oh YJ.

Autophagy. 2011 Jan;7(1):51-60. Epub 2011 Jan 1.

PMID:
21045561
[PubMed - indexed for MEDLINE]
Free Article
9.

Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: association with sequestosome 1/p62.

Myeku N, Figueiredo-Pereira ME.

J Biol Chem. 2011 Jun 24;286(25):22426-40. doi: 10.1074/jbc.M110.149252. Epub 2011 May 2.

PMID:
21536669
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Thioredoxin-interacting protein mediates dysfunction of tubular autophagy in diabetic kidneys through inhibiting autophagic flux.

Huang C, Lin MZ, Cheng D, Braet F, Pollock CA, Chen XM.

Lab Invest. 2014 Mar;94(3):309-20. doi: 10.1038/labinvest.2014.2. Epub 2014 Feb 3.

PMID:
24492284
[PubMed - indexed for MEDLINE]
Free Article
11.

Mechanism of destructive pathologic changes in the spinal cord under chronic mechanical compression.

Yamaura I, Yone K, Nakahara S, Nagamine T, Baba H, Uchida K, Komiya S.

Spine (Phila Pa 1976). 2002 Jan 1;27(1):21-6.

PMID:
11805631
[PubMed - indexed for MEDLINE]
12.

Enhanced p62 expression triggers concomitant autophagy and apoptosis in a rat chronic spinal cord compression model.

Chen Z, Fu Q, Shen B, Huang X, Wang K, He P, Li F, Zhang F, Shen H.

Mol Med Rep. 2014 Jun;9(6):2091-6. doi: 10.3892/mmr.2014.2124. Epub 2014 Apr 8.

PMID:
24715058
[PubMed - indexed for MEDLINE]
13.

Rapamycin treatment augments motor neuron degeneration in SOD1(G93A) mouse model of amyotrophic lateral sclerosis.

Zhang X, Li L, Chen S, Yang D, Wang Y, Zhang X, Wang Z, Le W.

Autophagy. 2011 Apr;7(4):412-25. Epub 2011 Apr 1.

PMID:
21193837
[PubMed - indexed for MEDLINE]
Free Article
14.

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.

Komatsu M, Waguri S, Koike M, Sou YS, Ueno T, Hara T, Mizushima N, Iwata J, Ezaki J, Murata S, Hamazaki J, Nishito Y, Iemura S, Natsume T, Yanagawa T, Uwayama J, Warabi E, Yoshida H, Ishii T, Kobayashi A, Yamamoto M, Yue Z, Uchiyama Y, Kominami E, Tanaka K.

Cell. 2007 Dec 14;131(6):1149-63.

PMID:
18083104
[PubMed - indexed for MEDLINE]
Free Article
15.

p62/sequestosome 1 as a regulator of proteasome inhibitor-induced autophagy in human retinal pigment epithelial cells.

Viiri J, Hyttinen JM, Ryhänen T, Rilla K, Paimela T, Kuusisto E, Siitonen A, Urtti A, Salminen A, Kaarniranta K.

Mol Vis. 2010 Jul 27;16:1399-414.

PMID:
20680098
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway.

Zheng YT, Shahnazari S, Brech A, Lamark T, Johansen T, Brumell JH.

J Immunol. 2009 Nov 1;183(9):5909-16. doi: 10.4049/jimmunol.0900441. Epub 2009 Oct 7.

PMID:
19812211
[PubMed - indexed for MEDLINE]
Free Article
17.

Spinal cord injury induces upregulation of Beclin 1 and promotes autophagic cell death.

Kanno H, Ozawa H, Sekiguchi A, Itoi E.

Neurobiol Dis. 2009 Feb;33(2):143-8. doi: 10.1016/j.nbd.2008.09.009. Epub 2008 Sep 30.

PMID:
18948195
[PubMed - indexed for MEDLINE]
18.

Axonal protection by Nmnat3 overexpression with involvement of autophagy in optic nerve degeneration.

Kitaoka Y, Munemasa Y, Kojima K, Hirano A, Ueno S, Takagi H.

Cell Death Dis. 2013 Oct 17;4:e860. doi: 10.1038/cddis.2013.391.

PMID:
24136224
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Nrf2-mediated induction of p62 controls Toll-like receptor-4-driven aggresome-like induced structure formation and autophagic degradation.

Fujita K, Maeda D, Xiao Q, Srinivasula SM.

Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1427-32. doi: 10.1073/pnas.1014156108. Epub 2011 Jan 10.

PMID:
21220332
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Depletion of the ubiquitin-binding adaptor molecule SQSTM1/p62 from macrophages harboring cftr ΔF508 mutation improves the delivery of Burkholderia cenocepacia to the autophagic machinery.

Abdulrahman BA, Khweek AA, Akhter A, Caution K, Tazi M, Hassan H, Zhang Y, Rowland PD, Malhotra S, Aeffner F, Davis IC, Valvano MA, Amer AO.

J Biol Chem. 2013 Jan 18;288(3):2049-58. doi: 10.1074/jbc.M112.411728. Epub 2012 Nov 12.

PMID:
23148214
[PubMed - indexed for MEDLINE]
Free PMC Article
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