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Results: 1 to 20 of 76

1.

RNA targets of wild-type and mutant FET family proteins.

Hoell JI, Larsson E, Runge S, Nusbaum JD, Duggimpudi S, Farazi TA, Hafner M, Borkhardt A, Sander C, Tuschl T.

Nat Struct Mol Biol. 2011 Nov 13;18(12):1428-31. doi: 10.1038/nsmb.2163.

PMID:
22081015
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A conserved N-terminal motif is required for complex formation between FUS, EWSR1, TAF15 and their oncogenic fusion proteins.

Thomsen C, Grundevik P, Elias P, Ståhlberg A, Aman P.

FASEB J. 2013 Dec;27(12):4965-74. doi: 10.1096/fj.13-234435. Epub 2013 Aug 23.

PMID:
23975937
[PubMed - indexed for MEDLINE]
3.

Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis.

Couthouis J, Hart MP, Erion R, King OD, Diaz Z, Nakaya T, Ibrahim F, Kim HJ, Mojsilovic-Petrovic J, Panossian S, Kim CE, Frackelton EC, Solski JA, Williams KL, Clay-Falcone D, Elman L, McCluskey L, Greene R, Hakonarson H, Kalb RG, Lee VM, Trojanowski JQ, Nicholson GA, Blair IP, Bonini NM, Van Deerlin VM, Mourelatos Z, Shorter J, Gitler AD.

Hum Mol Genet. 2012 Jul 1;21(13):2899-911. doi: 10.1093/hmg/dds116. Epub 2012 Mar 27.

PMID:
22454397
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations.

Neumann M, Bentmann E, Dormann D, Jawaid A, DeJesus-Hernandez M, Ansorge O, Roeber S, Kretzschmar HA, Munoz DG, Kusaka H, Yokota O, Ang LC, Bilbao J, Rademakers R, Haass C, Mackenzie IR.

Brain. 2011 Sep;134(Pt 9):2595-609. doi: 10.1093/brain/awr201. Epub 2011 Aug 19.

PMID:
21856723
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations.

Neumann M, Valori CF, Ansorge O, Kretzschmar HA, Munoz DG, Kusaka H, Yokota O, Ishihara K, Ang LC, Bilbao JM, Mackenzie IR.

Acta Neuropathol. 2012 Nov;124(5):705-16. doi: 10.1007/s00401-012-1020-6. Epub 2012 Jul 28.

PMID:
22842875
[PubMed - indexed for MEDLINE]
6.

Characterization and expression analysis in the developing embryonic brain of the porcine FET family: FUS, EWS, and TAF15.

Blechingberg J, Holm IE, Nielsen AL.

Gene. 2012 Feb 1;493(1):27-35. doi: 10.1016/j.gene.2011.11.038. Epub 2011 Nov 28.

PMID:
22143032
[PubMed - indexed for MEDLINE]
7.

FET proteins in frontotemporal dementia and amyotrophic lateral sclerosis.

Mackenzie IR, Neumann M.

Brain Res. 2012 Jun 26;1462:40-3. doi: 10.1016/j.brainres.2011.12.010. Epub 2011 Dec 13. Review.

PMID:
22261247
[PubMed - indexed for MEDLINE]
8.

mRNA and protein levels of FUS, EWSR1, and TAF15 are upregulated in liposarcoma.

Spitzer JI, Ugras S, Runge S, Decarolis P, Antonescu C, Tuschl T, Singer S.

Genes Chromosomes Cancer. 2011 May;50(5):338-47. doi: 10.1002/gcc.20858. Epub 2011 Feb 22.

PMID:
21344536
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Gene expression responses to FUS, EWS, and TAF15 reduction and stress granule sequestration analyses identifies FET-protein non-redundant functions.

Blechingberg J, Luo Y, Bolund L, Damgaard CK, Nielsen AL.

PLoS One. 2012;7(9):e46251. doi: 10.1371/journal.pone.0046251. Epub 2012 Sep 25.

PMID:
23049996
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

TDP-43 and FUS RNA-binding proteins bind distinct sets of cytoplasmic messenger RNAs and differently regulate their post-transcriptional fate in motoneuron-like cells.

Colombrita C, Onesto E, Megiorni F, Pizzuti A, Baralle FE, Buratti E, Silani V, Ratti A.

J Biol Chem. 2012 May 4;287(19):15635-47. doi: 10.1074/jbc.M111.333450. Epub 2012 Mar 16.

PMID:
22427648
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Mutational analysis reveals the FUS homolog TAF15 as a candidate gene for familial amyotrophic lateral sclerosis.

Ticozzi N, Vance C, Leclerc AL, Keagle P, Glass JD, McKenna-Yasek D, Sapp PC, Silani V, Bosco DA, Shaw CE, Brown RH Jr, Landers JE.

Am J Med Genet B Neuropsychiatr Genet. 2011 Apr;156B(3):285-90. doi: 10.1002/ajmg.b.31158. Epub 2011 Jan 13.

PMID:
21438137
[PubMed - indexed for MEDLINE]
12.

Domains involved in TAF15 subcellular localisation: dependence on cell type and ongoing transcription.

Marko M, Vlassis A, Guialis A, Leichter M.

Gene. 2012 Sep 15;506(2):331-8. doi: 10.1016/j.gene.2012.06.088. Epub 2012 Jul 3.

PMID:
22771914
[PubMed - indexed for MEDLINE]
13.

TDP-43 and FUS/TLS: sending a complex message about messenger RNA in amyotrophic lateral sclerosis?

Strong MJ, Volkening K.

FEBS J. 2011 Oct;278(19):3569-77. doi: 10.1111/j.1742-4658.2011.08277.x. Epub 2011 Sep 6. Review.

PMID:
21810174
[PubMed - indexed for MEDLINE]
14.

Amyotrophic lateral sclerosis-associated proteins TDP-43 and FUS/TLS function in a common biochemical complex to co-regulate HDAC6 mRNA.

Kim SH, Shanware NP, Bowler MJ, Tibbetts RS.

J Biol Chem. 2010 Oct 29;285(44):34097-105. doi: 10.1074/jbc.M110.154831. Epub 2010 Aug 18.

PMID:
20720006
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations.

Tradewell ML, Yu Z, Tibshirani M, Boulanger MC, Durham HD, Richard S.

Hum Mol Genet. 2012 Jan 1;21(1):136-49. doi: 10.1093/hmg/ddr448. Epub 2011 Sep 28.

PMID:
21965298
[PubMed - indexed for MEDLINE]
Free Article
16.

Genome wide array analysis indicates that an amyotrophic lateral sclerosis mutation of FUS causes an early increase of CAMK2N2 in vitro.

Convertini P, Zhang J, de la Grange P, Hayward LJ, Zhu H, Stamm S.

Biochim Biophys Acta. 2013 Aug;1832(8):1129-35. doi: 10.1016/j.bbadis.2013.03.015. Epub 2013 Mar 29.

PMID:
23545117
[PubMed - indexed for MEDLINE]
17.

The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response.

Andersson MK, Ståhlberg A, Arvidsson Y, Olofsson A, Semb H, Stenman G, Nilsson O, Aman P.

BMC Cell Biol. 2008 Jul 11;9:37. doi: 10.1186/1471-2121-9-37.

PMID:
18620564
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A yeast functional screen predicts new candidate ALS disease genes.

Couthouis J, Hart MP, Shorter J, DeJesus-Hernandez M, Erion R, Oristano R, Liu AX, Ramos D, Jethava N, Hosangadi D, Epstein J, Chiang A, Diaz Z, Nakaya T, Ibrahim F, Kim HJ, Solski JA, Williams KL, Mojsilovic-Petrovic J, Ingre C, Boylan K, Graff-Radford NR, Dickson DW, Clay-Falcone D, Elman L, McCluskey L, Greene R, Kalb RG, Lee VM, Trojanowski JQ, Ludolph A, Robberecht W, Andersen PM, Nicholson GA, Blair IP, King OD, Bonini NM, Van Deerlin V, Rademakers R, Mourelatos Z, Gitler AD.

Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):20881-90. doi: 10.1073/pnas.1109434108. Epub 2011 Nov 7.

PMID:
22065782
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Fused in sarcoma/translocated in liposarcoma: a multifunctional DNA/RNA binding protein.

Yang S, Warraich ST, Nicholson GA, Blair IP.

Int J Biochem Cell Biol. 2010 Sep;42(9):1408-11. doi: 10.1016/j.biocel.2010.06.003. Epub 2010 Jun 10.

PMID:
20541619
[PubMed - indexed for MEDLINE]
20.

FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis.

Deng HX, Zhai H, Bigio EH, Yan J, Fecto F, Ajroud K, Mishra M, Ajroud-Driss S, Heller S, Sufit R, Siddique N, Mugnaini E, Siddique T.

Ann Neurol. 2010 Jun;67(6):739-48. doi: 10.1002/ana.22051.

PMID:
20517935
[PubMed - indexed for MEDLINE]

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