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Items: 1 to 20 of 116

1.

Harnessing of the nucleosome-remodeling-deacetylase complex controls lymphocyte development and prevents leukemogenesis.

Zhang J, Jackson AF, Naito T, Dose M, Seavitt J, Liu F, Heller EJ, Kashiwagi M, Yoshida T, Gounari F, Petrie HT, Georgopoulos K.

Nat Immunol. 2011 Nov 13;13(1):86-94. doi: 10.1038/ni.2150.

2.

The IKAROS interaction with a complex including chromatin remodeling and transcription elongation activities is required for hematopoiesis.

Bottardi S, Mavoungou L, Pak H, Daou S, Bourgoin V, Lakehal YA, Affar el B, Milot E.

PLoS Genet. 2014 Dec 4;10(12):e1004827. doi: 10.1371/journal.pgen.1004827. eCollection 2014 Dec.

3.

Ikaros fingers on lymphocyte differentiation.

Yoshida T, Georgopoulos K.

Int J Hematol. 2014 Sep;100(3):220-9. doi: 10.1007/s12185-014-1644-5. Epub 2014 Aug 2. Review.

4.

Mi-2/NuRD chromatin remodeling complexes regulate B and T-lymphocyte development and function.

Dege C, Hagman J.

Immunol Rev. 2014 Sep;261(1):126-40. doi: 10.1111/imr.12209. Review.

5.

An ikaros-containing chromatin-remodeling complex in adult-type erythroid cells.

O'Neill DW, Schoetz SS, Lopez RA, Castle M, Rabinowitz L, Shor E, Krawchuk D, Goll MG, Renz M, Seelig HP, Han S, Seong RH, Park SD, Agalioti T, Munshi N, Thanos D, Erdjument-Bromage H, Tempst P, Bank A.

Mol Cell Biol. 2000 Oct;20(20):7572-82.

6.

Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros.

Schjerven H, McLaughlin J, Arenzana TL, Frietze S, Cheng D, Wadsworth SE, Lawson GW, Bensinger SJ, Farnham PJ, Witte ON, Smale ST.

Nat Immunol. 2013 Oct;14(10):1073-83. doi: 10.1038/ni.2707. Epub 2013 Sep 8.

7.

GATA-1 utilizes Ikaros and polycomb repressive complex 2 to suppress Hes1 and to promote erythropoiesis.

Ross J, Mavoungou L, Bresnick EH, Milot E.

Mol Cell Biol. 2012 Sep;32(18):3624-38. doi: 10.1128/MCB.00163-12. Epub 2012 Jul 9.

8.

Unconventional potentiation of gene expression by Ikaros.

Koipally J, Heller EJ, Seavitt JR, Georgopoulos K.

J Biol Chem. 2002 Apr 12;277(15):13007-15. Epub 2002 Jan 17.

9.

The chromatin remodeling complex NuRD establishes the poised state of rRNA genes characterized by bivalent histone modifications and altered nucleosome positions.

Xie W, Ling T, Zhou Y, Feng W, Zhu Q, Stunnenberg HG, Grummt I, Tao W.

Proc Natl Acad Sci U S A. 2012 May 22;109(21):8161-6. doi: 10.1073/pnas.1201262109. Epub 2012 May 8.

10.

Ikaros promotes rearrangement of TCR α genes in an Ikaros null thymoma cell line.

Collins B, Clambey ET, Scott-Browne J, White J, Marrack P, Hagman J, Kappler JW.

Eur J Immunol. 2013 Feb;43(2):521-32. doi: 10.1002/eji.201242757. Epub 2012 Dec 27.

11.

Predominant interaction of both Ikaros and Helios with the NuRD complex in immature thymocytes.

Sridharan R, Smale ST.

J Biol Chem. 2007 Oct 12;282(41):30227-38. Epub 2007 Aug 6.

12.

Antagonistic interactions between Ikaros and the chromatin remodeler Mi-2beta determine silencer activity and Cd4 gene expression.

Naito T, Gómez-Del Arco P, Williams CJ, Georgopoulos K.

Immunity. 2007 Nov;27(5):723-34. Epub 2007 Nov 1.

13.

MBD3, a component of the NuRD complex, facilitates chromatin alteration and deposition of epigenetic marks.

Morey L, Brenner C, Fazi F, Villa R, Gutierrez A, Buschbeck M, Nervi C, Minucci S, Fuks F, Di Croce L.

Mol Cell Biol. 2008 Oct;28(19):5912-23. doi: 10.1128/MCB.00467-08. Epub 2008 Jul 21.

14.

The Mi-2/NuRD complex: a critical epigenetic regulator of hematopoietic development, differentiation and cancer.

Ramírez J, Hagman J.

Epigenetics. 2009 Nov 16;4(8):532-6. Epub 2009 Nov 16. Review.

PMID:
19923891
15.

Opposing effects of SWI/SNF and Mi-2/NuRD chromatin remodeling complexes on epigenetic reprogramming by EBF and Pax5.

Gao H, Lukin K, Ramírez J, Fields S, Lopez D, Hagman J.

Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11258-63. doi: 10.1073/pnas.0809485106. Epub 2009 Jun 19.

16.

Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes.

Kim J, Sif S, Jones B, Jackson A, Koipally J, Heller E, Winandy S, Viel A, Sawyer A, Ikeda T, Kingston R, Georgopoulos K.

Immunity. 1999 Mar;10(3):345-55.

17.

Mi-2/NuRD complex making inroads into DNA-damage response pathway.

Li DQ, Kumar R.

Cell Cycle. 2010 Jun 1;9(11):2071-9. Epub 2010 Jun 1. Review.

18.

The chromatin remodeler Mi-2beta is required for CD4 expression and T cell development.

Williams CJ, Naito T, Arco PG, Seavitt JR, Cashman SM, De Souza B, Qi X, Keables P, Von Andrian UH, Georgopoulos K.

Immunity. 2004 Jun;20(6):719-33.

19.

Physical and functional interactions between the histone H3K4 demethylase KDM5A and the nucleosome remodeling and deacetylase (NuRD) complex.

Nishibuchi G, Shibata Y, Hayakawa T, Hayakawa N, Ohtani Y, Sinmyozu K, Tagami H, Nakayama J.

J Biol Chem. 2014 Oct 17;289(42):28956-70. doi: 10.1074/jbc.M114.573725. Epub 2014 Sep 4.

20.

The nucleosome remodeling and deacetylase chromatin remodeling (NuRD) complex is required for peripheral nerve myelination.

Hung H, Kohnken R, Svaren J.

J Neurosci. 2012 Feb 1;32(5):1517-27. doi: 10.1523/JNEUROSCI.2895-11.2012.

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