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Results: 1 to 20 of 140

1.

A sub-two minutes method for monoclonal antibody-aggregate quantification using parallel interlaced size exclusion high performance liquid chromatography.

Diederich P, Hansen SK, Oelmeier SA, Stolzenberger B, Hubbuch J.

J Chromatogr A. 2011 Dec 16;1218(50):9010-8. doi: 10.1016/j.chroma.2011.09.086. Epub 2011 Oct 25.

PMID:
22078232
[PubMed - indexed for MEDLINE]
2.

Interlaced size exclusion liquid chromatography of monoclonal antibodies.

Farnan D, Moreno GT, Stults J, Becker A, Tremintin G, van Gils M.

J Chromatogr A. 2009 Dec 18;1216(51):8904-9. doi: 10.1016/j.chroma.2009.10.045. Epub 2009 Oct 20.

PMID:
19909961
[PubMed - indexed for MEDLINE]
3.

A high-throughput UPLC method for the characterization of chemical modifications in monoclonal antibody molecules.

Stackhouse N, Miller AK, Gadgil HS.

J Pharm Sci. 2011 Dec;100(12):5115-25. doi: 10.1002/jps.22710. Epub 2011 Jul 24.

PMID:
21789770
[PubMed - indexed for MEDLINE]
4.

Analysis of reduced monoclonal antibodies using size exclusion chromatography coupled with mass spectrometry.

Liu H, Gaza-Bulseco G, Chumsae C.

J Am Soc Mass Spectrom. 2009 Dec;20(12):2258-64. doi: 10.1016/j.jasms.2009.08.015. Epub 2009 Aug 28.

PMID:
19786356
[PubMed - indexed for MEDLINE]
Free Article
5.

Fast, reproducible size-exclusion chromatography of biological macromolecules.

Ricker RD, Sandoval LA.

J Chromatogr A. 1996 Aug 30;743(1):43-50.

PMID:
8817873
[PubMed - indexed for MEDLINE]
6.
7.

On-line coupling of size exclusion chromatography with mixed-mode liquid chromatography for comprehensive profiling of biopharmaceutical drug product.

He Y, Friese OV, Schlittler MR, Wang Q, Yang X, Bass LA, Jones MT.

J Chromatogr A. 2012 Nov 2;1262:122-9. doi: 10.1016/j.chroma.2012.09.012. Epub 2012 Sep 10.

PMID:
22999205
[PubMed - indexed for MEDLINE]
8.

Direct determination of residual Pluronic F-68 in in-process samples from monoclonal antibody preparations by high performance liquid chromatography.

Chung HH, Zhou C, Khor HK, Qiu J.

J Chromatogr A. 2011 Apr 15;1218(15):2106-13. doi: 10.1016/j.chroma.2010.12.073. Epub 2010 Dec 23.

PMID:
21227430
[PubMed - indexed for MEDLINE]
9.

Quantification of immunoglobulin G and characterization of process related impurities using coupled protein A and size exclusion high performance liquid chromatography.

Horak J, Ronacher A, Lindner W.

J Chromatogr A. 2010 Jul 30;1217(31):5092-102. doi: 10.1016/j.chroma.2010.06.007. Epub 2010 Jun 9.

PMID:
20580008
[PubMed - indexed for MEDLINE]
10.

Rapid quantification of protein-polyethylene glycol conjugates by multivariate evaluation of chromatographic data.

Hansen SK, Maiser B, Hubbuch J.

J Chromatogr A. 2012 Sep 28;1257:41-7. doi: 10.1016/j.chroma.2012.07.089. Epub 2012 Aug 3.

PMID:
22920306
[PubMed - indexed for MEDLINE]
11.

Process and product monitoring of recombinant DNA-derived biopharmaceuticals with high-performance capillary electrophoresis.

Sunday BR, Sydor W, Guariglia LM, Obara J, Mengisen R.

J Capill Electrophor Microchip Technol. 2003 Sep-Dec;8(5-6):87-99.

PMID:
15369173
[PubMed - indexed for MEDLINE]
12.

A label-free methodology for selective protein quantification by means of absorption measurements.

Hansen SK, Skibsted E, Staby A, Hubbuch J.

Biotechnol Bioeng. 2011 Nov;108(11):2661-9. doi: 10.1002/bit.23229. Epub 2011 Jul 13.

PMID:
21755495
[PubMed - indexed for MEDLINE]
13.

Quantitation of aggregate levels in a recombinant humanized monoclonal antibody formulation by size-exclusion chromatography, asymmetrical flow field flow fractionation, and sedimentation velocity.

Gabrielson JP, Brader ML, Pekar AH, Mathis KB, Winter G, Carpenter JF, Randolph TW.

J Pharm Sci. 2007 Feb;96(2):268-79.

PMID:
17080424
[PubMed - indexed for MEDLINE]
14.

Subvisible particle counting provides a sensitive method of detecting and quantifying aggregation of monoclonal antibody caused by freeze-thawing: insights into the roles of particles in the protein aggregation pathway.

Barnard JG, Singh S, Randolph TW, Carpenter JF.

J Pharm Sci. 2011 Feb;100(2):492-503. doi: 10.1002/jps.22305. Epub 2010 Aug 27.

PMID:
20803602
[PubMed - indexed for MEDLINE]
15.

Non-size-based membrane chromatographic separation and analysis of monoclonal antibody aggregates.

Wang L, Hale G, Ghosh R.

Anal Chem. 2006 Oct 1;78(19):6863-7.

PMID:
17007507
[PubMed - indexed for MEDLINE]
16.

High throughput liquid chromatography with sub-2 microm particles at high pressure and high temperature.

Nguyen DT, Guillarme D, Heinisch S, Barrioulet MP, Rocca JL, Rudaz S, Veuthey JL.

J Chromatogr A. 2007 Oct 5;1167(1):76-84. Epub 2007 Aug 17.

PMID:
17765255
[PubMed - indexed for MEDLINE]
17.

Microheterogeneous monoclonal antibody subspecies with differential hepatitis C virus core antigen binding properties identified by SEC-HPLC.

Muerhoff AS, Rupprecht K, Ruan Q, Zeck B, Ramsay C, Zhao C, Desai SM.

J Immunol Methods. 2009 Jun 30;345(1-2):60-9. doi: 10.1016/j.jim.2009.04.004. Epub 2009 Apr 16.

PMID:
19375428
[PubMed - indexed for MEDLINE]
18.

Facile method of quantification for oxidized tryptophan degradants of monoclonal antibody by mixed mode ultra performance liquid chromatography.

Wong C, Strachan-Mills C, Burman S.

J Chromatogr A. 2012 Dec 28;1270:153-61. doi: 10.1016/j.chroma.2012.10.064. Epub 2012 Nov 5.

PMID:
23182937
[PubMed - indexed for MEDLINE]
19.

Evaluation of a dual-wavelength size exclusion HPLC method with improved sensitivity to detect protein aggregates and its use to better characterize degradation pathways of an IgG1 monoclonal antibody.

Bond MD, Panek ME, Zhang Z, Wang D, Mehndiratta P, Zhao H, Gunton K, Ni A, Nedved ML, Burman S, Volkin DB.

J Pharm Sci. 2010 Jun;99(6):2582-97. doi: 10.1002/jps.22034.

PMID:
20039394
[PubMed - indexed for MEDLINE]
20.

Characterization and analysis of thermal denaturation of antibodies by size exclusion high-performance liquid chromatography with quadruple detection.

Hartmann WK, Saptharishi N, Yang XY, Mitra G, Soman G.

Anal Biochem. 2004 Feb 15;325(2):227-39.

PMID:
14751257
[PubMed - indexed for MEDLINE]

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