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Results: 1 to 20 of 126

1.

Structure-guided engineering of human thymidine kinase 2 as a positron emission tomography reporter gene for enhanced phosphorylation of non-natural thymidine analog reporter probe.

Campbell DO, Yaghoubi SS, Su Y, Lee JT, Auerbach MS, Herschman H, Satyamurthy N, Czernin J, Lavie A, Radu CG.

J Biol Chem. 2012 Jan 2;287(1):446-54. doi: 10.1074/jbc.M111.314666. Epub 2011 Nov 9.

PMID:
22074768
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Molecular-genetic PET imaging using an HSV1-tk mutant reporter gene with enhanced specificity to acycloguanosine nucleoside analogs.

Najjar AM, Nishii R, Maxwell DS, Volgin A, Mukhopadhyay U, Bornmann WG, Tong W, Alauddin M, Gelovani JG.

J Nucl Med. 2009 Mar;50(3):409-16. doi: 10.2967/jnumed.108.058735. Epub 2009 Feb 17.

PMID:
19223410
[PubMed - indexed for MEDLINE]
Free Article
3.

Evaluation of F-18-labeled 5-iodocytidine (18F-FIAC) as a new potential positron emission tomography probe for herpes simplex virus type 1 thymidine kinase imaging.

Chan PC, Wu CY, Chang WY, Chang WT, Alauddin M, Liu RS, Lin WJ, Chen FD, Chen CL, Wang HE.

Nucl Med Biol. 2011 Oct;38(7):987-95. doi: 10.1016/j.nucmedbio.2011.04.003. Epub 2011 Jun 22.

PMID:
21982570
[PubMed - indexed for MEDLINE]
4.

18F-FEAU as a radiotracer for herpes simplex virus thymidine kinase gene expression: in-vitro comparison with other PET tracers.

Buursma AR, Rutgers V, Hospers GA, Mulder NH, Vaalburg W, de Vries EF.

Nucl Med Commun. 2006 Jan;27(1):25-30.

PMID:
16340720
[PubMed - indexed for MEDLINE]
5.

Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in a human breast cancer model.

Alauddin MM, Shahinian A, Gordon EM, Conti PS.

Mol Imaging. 2004 Apr;3(2):76-84.

PMID:
15296672
[PubMed - indexed for MEDLINE]
6.

PET of cardiac transgene expression: comparison of 2 approaches based on herpesviral thymidine kinase reporter gene.

Miyagawa M, Anton M, Haubner R, Simoes MV, St├Ądele C, Erhardt W, Reder S, Lehner T, Wagner B, Noll S, Noll B, Grote M, Gambhir SS, Gansbacher B, Schwaiger M, Bengel FM.

J Nucl Med. 2004 Nov;45(11):1917-23.

PMID:
15534063
[PubMed - indexed for MEDLINE]
Free Article
7.

A new acycloguanosine-specific supermutant of herpes simplex virus type 1 thymidine kinase suitable for PET imaging and suicide gene therapy for potential use in patients treated with pyrimidine-based cytotoxic drugs.

Likar Y, Dobrenkov K, Olszewska M, Vider E, Shenker L, Cai S, Pillarsetty N, Hricak H, Ponomarev V.

J Nucl Med. 2008 May;49(5):713-20. doi: 10.2967/jnumed.107.046425. Epub 2008 Apr 15.

PMID:
18413388
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Comparison of [18F]FHPG and [124/125I]FIAU for imaging herpes simplex virus type 1 thymidine kinase gene expression.

Brust P, Haubner R, Friedrich A, Scheunemann M, Anton M, Koufaki ON, Hauses M, Noll S, Noll B, Haberkorn U, Schackert G, Schackert HK, Avril N, Johannsen B.

Eur J Nucl Med. 2001 Jun;28(6):721-9.

PMID:
11440032
[PubMed - indexed for MEDLINE]
9.
10.

Construction and validation of improved triple fusion reporter gene vectors for molecular imaging of living subjects.

Ray P, Tsien R, Gambhir SS.

Cancer Res. 2007 Apr 1;67(7):3085-93.

PMID:
17409415
[PubMed - indexed for MEDLINE]
Free Article
11.

A tracer kinetic model for 18F-FHBG for quantitating herpes simplex virus type 1 thymidine kinase reporter gene expression in living animals using PET.

Green LA, Nguyen K, Berenji B, Iyer M, Bauer E, Barrio JR, Namavari M, Satyamurthy N, Gambhir SS.

J Nucl Med. 2004 Sep;45(9):1560-70.

PMID:
15347725
[PubMed - indexed for MEDLINE]
Free Article
12.

Preliminary validation of varicella zoster virus thymidine kinase as a novel reporter gene for PET.

Deroose CM, Chitneni SK, Gijsbers R, Vermaelen P, Ibrahimi A, Balzarini J, Baekelandt V, Verbruggen A, Nuyts J, Debyser Z, Bormans GM, Mortelmans L.

Nucl Med Biol. 2012 Nov;39(8):1266-74. doi: 10.1016/j.nucmedbio.2012.06.014. Epub 2012 Sep 14.

PMID:
22981986
[PubMed - indexed for MEDLINE]
13.

5-[18F]Fluoroalkyl pyrimidine nucleosides: probes for positron emission tomography imaging of herpes simplex virus type 1 thymidine kinase gene expression.

Chacko AM, Blankemeyer E, Lieberman BP, Qu W, Kung HF.

Nucl Med Biol. 2009 Jan;36(1):29-38. doi: 10.1016/j.nucmedbio.2008.10.009.

PMID:
19181266
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Evaluation of 2'-deoxy-2'-[18F]fluoro-5-methyl-1-beta-L: -arabinofuranosyluracil ([18F]-L: -FMAU) as a PET imaging agent for cellular proliferation: comparison with [18F]-D: -FMAU and [18F]FLT.

Nishii R, Volgin AY, Mawlawi O, Mukhopadhyay U, Pal A, Bornmann W, Gelovani JG, Alauddin MM.

Eur J Nucl Med Mol Imaging. 2008 May;35(5):990-8. Epub 2007 Dec 4.

PMID:
18057932
[PubMed - indexed for MEDLINE]
15.

Molecular PET imaging of HSV1-tk reporter gene expression using [18F]FEAU.

Soghomonyan S, Hajitou A, Rangel R, Trepel M, Pasqualini R, Arap W, Gelovani JG, Alauddin MM.

Nat Protoc. 2007;2(2):416-23.

PMID:
17406603
[PubMed - indexed for MEDLINE]
16.

Synthesis and evaluation of 2'-deoxy-2'-18F-fluoro-5-fluoro-1-beta-D-arabinofuranosyluracil as a potential PET imaging agent for suicide gene expression.

Alauddin MM, Shahinian A, Park R, Tohme M, Fissekis JD, Conti PS.

J Nucl Med. 2004 Dec;45(12):2063-9.

PMID:
15585483
[PubMed - indexed for MEDLINE]
Free Article
17.

Application of a rapid, simple, and accurate adenovirus-based method to compare PET reporter gene/PET reporter probe systems.

Gil JS, Machado HB, Campbell DO, McCracken M, Radu C, Witte ON, Herschman HR.

Mol Imaging Biol. 2013 Jun;15(3):273-81. doi: 10.1007/s11307-012-0596-5.

PMID:
23054556
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Repetitive noninvasive monitoring of HSV1-tk-expressing T cells intravenously infused into nonhuman primates using positron emission tomography and computed tomography with 18F-FEAU.

Dotti G, Tian M, Savoldo B, Najjar A, Cooper LJ, Jackson J, Smith A, Mawlawi O, Uthamanthil R, Borne A, Brammer D, Paolillo V, Alauddin M, Gonzalez C, Steiner D, Decker WK, Marini F, Kornblau S, Bollard CM, Shpall EJ, Gelovani JG.

Mol Imaging. 2009 Jul-Aug;8(4):230-7.

PMID:
19728977
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

A new pyrimidine-specific reporter gene: a mutated human deoxycytidine kinase suitable for PET during treatment with acycloguanosine-based cytotoxic drugs.

Likar Y, Zurita J, Dobrenkov K, Shenker L, Cai S, Neschadim A, Medin JA, Sadelain M, Hricak H, Ponomarev V.

J Nucl Med. 2010 Sep;51(9):1395-403. doi: 10.2967/jnumed.109.074344.

PMID:
20810757
[PubMed - indexed for MEDLINE]
Free Article
20.

Imaging progress of herpes simplex virus type 1 thymidine kinase suicide gene therapy in living subjects with positron emission tomography.

Yaghoubi SS, Barrio JR, Namavari M, Satyamurthy N, Phelps ME, Herschman HR, Gambhir SS.

Cancer Gene Ther. 2005 Mar;12(3):329-39.

PMID:
15592447
[PubMed - indexed for MEDLINE]

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