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Items: 1 to 20 of 121

1.

Comparison of Comet assay dose-response for ethyl methanesulfonate using freshly prepared versus cryopreserved tissues.

Recio L, Kissling GE, Hobbs CA, Witt KL.

Environ Mol Mutagen. 2012 Mar;53(2):101-13. doi: 10.1002/em.20694. Epub 2011 Nov 8.

PMID:
22069077
2.

Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies.

Rothfuss A, O'Donovan M, De Boeck M, Brault D, Czich A, Custer L, Hamada S, Plappert-Helbig U, Hayashi M, Howe J, Kraynak AR, van der Leede BJ, Nakajima M, Priestley C, Thybaud V, Saigo K, Sawant S, Shi J, Storer R, Struwe M, Vock E, Galloway S.

Mutat Res. 2010 Sep 30;702(1):40-69. doi: 10.1016/j.mrgentox.2010.07.006. Epub 2010 Jul 23.

PMID:
20656055
3.
4.
5.

Vehicle and positive control values from the in vivo rodent comet assay and biomonitoring studies using human lymphocytes: historical database and influence of technical aspects.

Pant K, Springer S, Bruce S, Lawlor T, Hewitt N, Aardema MJ.

Environ Mol Mutagen. 2014 Oct;55(8):633-42. doi: 10.1002/em.21881. Epub 2014 Jun 23.

PMID:
24957907
6.

Evaluation of the Pig-a, micronucleus, and comet assay endpoints in a 28-day study with ethyl methanesulfonate.

Gunther WC, Coffing SL, Dickinson DA, Engel ME, Fiedler RD, O'Lone SD, Sanok KE, Thiffeault CJ, Shutsky TJ, Schuler MJ, Dobo KL.

Environ Mol Mutagen. 2014 Jul;55(6):492-9. doi: 10.1002/em.21863. Epub 2014 Mar 6.

PMID:
24599777
7.

Assessment of genotoxicity induced by 7,12-dimethylbenz(a)anthracene or diethylnitrosamine in the Pig-a, micronucleus and Comet assays integrated into 28-day repeat dose studies.

Shi J, Krsmanovic L, Bruce S, Kelly T, Paranjpe M, Szabo K, Arevalo M, Atta-Safoh S, Debelie F, LaForce MK, Sly J, Springer S.

Environ Mol Mutagen. 2011 Dec;52(9):711-20. doi: 10.1002/em.20678. Epub 2011 Oct 4.

PMID:
21976072
9.

Validation of Drosophila melanogaster as an in vivo model for genotoxicity assessment using modified alkaline Comet assay.

Siddique HR, Chowdhuri DK, Saxena DK, Dhawan A.

Mutagenesis. 2005 Jul;20(4):285-90. Epub 2005 May 17.

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11.

Influence of experimental conditions on data variability in the liver comet assay.

Guérard M, Marchand C, Plappert-Helbig U.

Environ Mol Mutagen. 2014 Mar;55(2):114-21. doi: 10.1002/em.21835. Epub 2013 Dec 18.

PMID:
24346955
12.

Ethyl methanesulfonate toxicity in Viracept--a comprehensive human risk assessment based on threshold data for genotoxicity.

Müller L, Gocke E, Lavé T, Pfister T.

Toxicol Lett. 2009 Nov 12;190(3):317-29. doi: 10.1016/j.toxlet.2009.04.003. Epub 2009 Apr 10.

PMID:
19443141
13.

Alkaline comet assay in liver and stomach, and micronucleus assay in bone marrow, from rats treated with 2-acetylaminofluorene, azidothymidine, cisplatin, or isobutyraldehyde.

Kraynak AR, Barnum JE, Cunningham CL, Ng A, Ykoruk BA, Bennet B, Stoffregen D, Merschman M, Freeland E, Galloway SM.

Mutat Res Genet Toxicol Environ Mutagen. 2015 Jul;786-788:77-86. doi: 10.1016/j.mrgentox.2015.03.005. Epub 2015 Mar 5.

PMID:
26212296
14.

In vivo Comet assay on isolated kidney cells to distinguish genotoxic carcinogens from epigenetic carcinogens or cytotoxic compounds.

Nesslany F, Zennouche N, Simar-Meintières S, Talahari I, Nkili-Mboui EN, Marzin D.

Mutat Res. 2007 Jun 15;630(1-2):28-41. Epub 2007 Apr 19.

PMID:
17507283
15.

The comet assay with multiple mouse organs: comparison of comet assay results and carcinogenicity with 208 chemicals selected from the IARC monographs and U.S. NTP Carcinogenicity Database.

Sasaki YF, Sekihashi K, Izumiyama F, Nishidate E, Saga A, Ishida K, Tsuda S.

Crit Rev Toxicol. 2000 Nov;30(6):629-799. Review.

PMID:
11145306
17.

Improvement of in vivo genotoxicity assessment: combination of acute tests and integration into standard toxicity testing.

Rothfuss A, Honma M, Czich A, Aardema MJ, Burlinson B, Galloway S, Hamada S, Kirkland D, Heflich RH, Howe J, Nakajima M, O'Donovan M, Plappert-Helbig U, Priestley C, Recio L, Schuler M, Uno Y, Martus HJ.

Mutat Res. 2011 Aug 16;723(2):108-20. doi: 10.1016/j.mrgentox.2010.12.005. Epub 2010 Dec 21.

PMID:
21182982
18.

Evaluation of a multi-endpoint assay in rats, combining the bone-marrow micronucleus test, the Comet assay and the flow-cytometric peripheral blood micronucleus test.

Bowen DE, Whitwell JH, Lillford L, Henderson D, Kidd D, Mc Garry S, Pearce G, Beevers C, Kirkland DJ; Work conducted at Covance Laboratories Ltd., Harrogate.

Mutat Res. 2011 May 18;722(1):7-19. doi: 10.1016/j.mrgentox.2011.02.009. Epub 2011 Feb 25.

PMID:
21356328
20.

Evaluation of multi-organ DNA damage by comet assay from 28 days repeated dose oral toxicity test in mice: a practical approach for test integration in regulatory toxicity testing.

Kushwaha S, Tripathi DN, Vikram A, Ramarao P, Jena GB.

Regul Toxicol Pharmacol. 2010 Oct;58(1):145-54. doi: 10.1016/j.yrtph.2010.05.004. Epub 2010 May 19.

PMID:
20488216
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