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Related Citations for PubMed (Select 22064482)


Hypergrowth mTORC1 signals translationally activate the ARF tumor suppressor checkpoint.

Miceli AP, Saporita AJ, Weber JD.

Mol Cell Biol. 2012 Jan;32(2):348-64. doi: 10.1128/MCB.06030-11. Epub 2011 Nov 7.


The ARF tumor-suppressor controls Drosha translation to prevent Ras-driven transformation.

Kuchenreuther MJ, Weber JD.

Oncogene. 2014 Jan 16;33(3):300-7. doi: 10.1038/onc.2012.601. Epub 2013 Jan 14.


P19ARF and RasV¹² offer opposing regulation of DHX33 translation to dictate tumor cell fate.

Zhang Y, Saporita AJ, Weber JD.

Mol Cell Biol. 2013 Apr;33(8):1594-607. doi: 10.1128/MCB.01220-12. Epub 2013 Feb 11.


Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation.

Lin AW, Lowe SW.

Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):5025-30. Epub 2001 Apr 17.


Mutually exclusive inactivation of DMP1 and ARF/p53 in lung cancer.

Mallakin A, Sugiyama T, Taneja P, Matise LA, Frazier DP, Choudhary M, Hawkins GA, D'Agostino RB Jr, Willingham MC, Inoue K.

Cancer Cell. 2007 Oct;12(4):381-94.


Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor.

Sreeramaneni R, Chaudhry A, McMahon M, Sherr CJ, Inoue K.

Mol Cell Biol. 2005 Jan;25(1):220-32.


Deregulated beta-catenin induces a p53- and ARF-dependent growth arrest and cooperates with Ras in transformation.

Damalas A, Kahan S, Shtutman M, Ben-Ze'ev A, Oren M.

EMBO J. 2001 Sep 3;20(17):4912-22.


Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence.

Zou X, Ray D, Aziyu A, Christov K, Boiko AD, Gudkov AV, Kiyokawa H.

Genes Dev. 2002 Nov 15;16(22):2923-34.


p19(ARF) is dispensable for oncogenic stress-induced p53-mediated apoptosis and tumor suppression in vivo.

Tolbert D, Lu X, Yin C, Tantama M, Van Dyke T.

Mol Cell Biol. 2002 Jan;22(1):370-7.


Disruption of the ARF transcriptional activator DMP1 facilitates cell immortalization, Ras transformation, and tumorigenesis.

Inoue K, Wen R, Rehg JE, Adachi M, Cleveland JL, Roussel MF, Sherr CJ.

Genes Dev. 2000 Jul 15;14(14):1797-809.


The LIM-only protein FHL2 mediates ras-induced transformation through cyclin D1 and p53 pathways.

Labalette C, Nouët Y, Levillayer F, Armengol C, Renard CA, Soubigou G, Xia T, Buendia MA, Wei Y.

PLoS One. 2008;3(11):e3761. doi: 10.1371/journal.pone.0003761. Epub 2008 Nov 19.


p53-Dependent and -independent functions of the Arf tumor suppressor.

Sherr CJ, Bertwistle D, DEN Besten W, Kuo ML, Sugimoto M, Tago K, Williams RT, Zindy F, Roussel MF.

Cold Spring Harb Symp Quant Biol. 2005;70:129-37. Review.


Induction of ARF tumor suppressor gene expression and cell cycle arrest by transcription factor DMP1.

Inoue K, Roussel MF, Sherr CJ.

Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3993-8.


E2F transcriptional repressor complexes are critical downstream targets of p19(ARF)/p53-induced proliferative arrest.

Rowland BD, Denissov SG, Douma S, Stunnenberg HG, Bernards R, Peeper DS.

Cancer Cell. 2002 Jul;2(1):55-65.


Dmp1 and tumor suppression.

Inoue K, Mallakin A, Frazier DP.

Oncogene. 2007 Jun 28;26(30):4329-35. Epub 2007 Jan 22. Review.


Tissue-specific p19Arf regulation dictates the response to oncogenic K-ras.

Young NP, Jacks T.

Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10184-9. doi: 10.1073/pnas.1004796107. Epub 2010 May 17.


Oncogenic ras and p53 cooperate to induce cellular senescence.

Ferbeyre G, de Stanchina E, Lin AW, Querido E, McCurrach ME, Hannon GJ, Lowe SW.

Mol Cell Biol. 2002 May;22(10):3497-508.


Disruption of the Cockayne syndrome B gene impairs spontaneous tumorigenesis in cancer-predisposed Ink4a/ARF knockout mice.

Lu Y, Lian H, Sharma P, Schreiber-Agus N, Russell RG, Chin L, van der Horst GT, Bregman DB.

Mol Cell Biol. 2001 Mar;21(5):1810-8.

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