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Items: 1 to 20 of 85

1.

Novel adiponectin variants identified in type 2 diabetic patients reveal multimerization and secretion defects.

Jungtrakoon P, Plengvidhya N, Tangjittipokin W, Chimnaronk S, Salaemae W, Chongjaroen N, Chanprasert K, Sujjitjoon J, Srisawat C, Yenchitsomanus PT.

PLoS One. 2011;6(10):e26792. doi: 10.1371/journal.pone.0026792. Epub 2011 Oct 26.

2.

Intracellular trafficking and secretion of adiponectin is dependent on GGA-coated vesicles.

Xie L, Boyle D, Sanford D, Scherer PE, Pessin JE, Mora S.

J Biol Chem. 2006 Mar 17;281(11):7253-9. Epub 2005 Dec 29.

3.

Deep resequencing unveils genetic architecture of ADIPOQ and identifies a novel low-frequency variant strongly associated with adiponectin variation.

Warren LL, Li L, Nelson MR, Ehm MG, Shen J, Fraser DJ, Aponte JL, Nangle KL, Slater AJ, Woollard PM, Hall MD, Topp SD, Yuan X, Cardon LR, Chissoe SL, Mooser V, Morris AD, Palmer CN, Perry JR, Frayling TM, Whittaker JC, Waterworth DM.

Diabetes. 2012 May;61(5):1297-301. doi: 10.2337/db11-0985. Epub 2012 Mar 8.

4.

A novel ADIPOQ mutation (p.M40K) impairs assembly of high-molecular-weight adiponectin and is associated with early-onset obesity and metabolic syndrome.

Bueno AC, Sun K, Martins CS, Elias Junior J, Miranda W, Tao C, Foss-Freitas MC, Barbieri MA, Bettiol H, de Castro M, Scherer PE, Antonini SR.

J Clin Endocrinol Metab. 2014 Apr;99(4):E683-93. doi: 10.1210/jc.2013-3009. Epub 2014 Jan 16.

PMID:
24432991
5.

Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin.

Waki H, Yamauchi T, Kamon J, Ito Y, Uchida S, Kita S, Hara K, Hada Y, Vasseur F, Froguel P, Kimura S, Nagai R, Kadowaki T.

J Biol Chem. 2003 Oct 10;278(41):40352-63. Epub 2003 Jul 23.

6.

Novel mutation in the adiponectin (ADIPOQ) gene is associated with hypoadiponectinaemia in Japanese-Brazilians.

Vendramini MF, Kasamatsu TS, Crispim F, Ferreira SR, Matioli SR; Japanese-Brazilian Diabetes Study Group, Moisés RS.

Clin Endocrinol (Oxf). 2009 Jul;71(1):50-5. doi: 10.1111/j.1365-2265.2008.03439.x. Epub 2008 Sep 28.

PMID:
19178518
7.

Hypoadiponectinemia is associated with progression toward type 2 diabetes and genetic variation in the ADIPOQ gene promoter.

Schwarz PE, Towers GW, Fischer S, Govindarajalu S, Schulze J, Bornstein SR, Hanefeld M, Vasseur F.

Diabetes Care. 2006 Jul;29(7):1645-50.

PMID:
16801592
8.

Sialic acid modification of adiponectin is not required for multimerization or secretion but determines half-life in circulation.

Richards AA, Colgrave ML, Zhang J, Webster J, Simpson F, Preston E, Wilks D, Hoehn KL, Stephenson M, Macdonald GA, Prins JB, Cooney GJ, Xu A, Whitehead JP.

Mol Endocrinol. 2010 Jan;24(1):229-39. doi: 10.1210/me.2009-0133. Epub 2009 Oct 23.

PMID:
19855092
9.

Selective regulation of cellular and secreted multimeric adiponectin by antidiabetic therapies in humans.

Phillips SA, Kung J, Ciaraldi TP, Choe C, Christiansen L, Mudaliar S, Henry RR.

Am J Physiol Endocrinol Metab. 2009 Sep;297(3):E767-73. doi: 10.1152/ajpendo.00378.2009. Epub 2009 Jul 21.

10.

Adiponectin, type 2 diabetes and the metabolic syndrome: lessons from human genetic studies.

Vasseur F, Meyre D, Froguel P.

Expert Rev Mol Med. 2006 Nov 20;8(27):1-12. Review.

PMID:
17112391
12.

Specific amino-acid residues in the N-terminus and TM3 implicated in channel function and oligomerization compatibility of connexin43.

Lagree V, Brunschwig K, Lopez P, Gilula NB, Richard G, Falk MM.

J Cell Sci. 2003 Aug 1;116(Pt 15):3189-201.

13.

Arc is a flexible modular protein capable of reversible self-oligomerization.

Myrum C, Baumann A, Bustad HJ, Flydal MI, Mariaule V, Alvira S, Cuéllar J, Haavik J, Soulé J, Valpuesta JM, Márquez JA, Martinez A, Bramham CR.

Biochem J. 2015 May 15;468(1):145-58. doi: 10.1042/BJ20141446.

14.

Association and interaction analyses of genetic variants in ADIPOQ, ENPP1, GHSR, PPARgamma and TCF7L2 genes for diabetic nephropathy in a Taiwanese population with type 2 diabetes.

Wu LS, Hsieh CH, Pei D, Hung YJ, Kuo SW, Lin E.

Nephrol Dial Transplant. 2009 Nov;24(11):3360-6. doi: 10.1093/ndt/gfp271. Epub 2009 Jun 8.

15.

Common adiponectin gene variants show different effects on risk of cardiovascular disease and type 2 diabetes in European subjects.

Gable DR, Matin J, Whittall R, Cakmak H, Li KW, Cooper J, Miller GJ, Humphries SE; HIFMECH investigators.

Ann Hum Genet. 2007 Jul;71(Pt 4):453-66. Epub 2007 Jan 11.

16.

Single-nucleotide polymorphisms and haplotypes in the adiponectin gene contribute to the genetic risk for type 2 diabetes in Tunisian Arabs.

Mtiraoui N, Ezzidi I, Turki A, Chaieb A, Mahjoub T, Almawi WY.

Diabetes Res Clin Pract. 2012 Aug;97(2):290-7. doi: 10.1016/j.diabres.2012.02.015. Epub 2012 Apr 11.

PMID:
22497971
17.

Association of ADIPOQ variants, total and high molecular weight adiponectin levels with coronary artery disease in diabetic and non-diabetic Brazilian subjects.

Oliveira CS, Saddi-Rosa P, Crispim F, Canani LH, Gerchman F, Giuffrida FM, Vieira JG, Velho G, Reis AF.

J Diabetes Complications. 2012 Mar-Apr;26(2):94-8. doi: 10.1016/j.jdiacomp.2012.02.008. Epub 2012 Mar 27.

PMID:
22459242
18.

Adiponectin--it's all about the modifications.

Simpson F, Whitehead JP.

Int J Biochem Cell Biol. 2010 Jun;42(6):785-8. doi: 10.1016/j.biocel.2009.12.021. Epub 2010 Jan 4. Review.

PMID:
20044026
19.

Haplotypes in the promoter region of the ADIPOQ gene are associated with increased diabetes risk in a German Caucasian population.

Schwarz PE, Govindarajalu S, Towers W, Schwanebeck U, Fischer S, Vasseur F, Bornstein SR, Schulze J.

Horm Metab Res. 2006 Jul;38(7):447-51.

PMID:
16933180
20.

Association of adiponectin mutation with type 2 diabetes: a candidate gene for the insulin resistance syndrome.

Kondo H, Shimomura I, Matsukawa Y, Kumada M, Takahashi M, Matsuda M, Ouchi N, Kihara S, Kawamoto T, Sumitsuji S, Funahashi T, Matsuzawa Y.

Diabetes. 2002 Jul;51(7):2325-8.

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