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Results: 1 to 20 of 110

1.

Correct end use during end joining of multiple chromosomal double strand breaks is influenced by repair protein RAD50, DNA-dependent protein kinase DNA-PKcs, and transcription context.

Gunn A, Bennardo N, Cheng A, Stark JM.

J Biol Chem. 2011 Dec 9;286(49):42470-82. doi: 10.1074/jbc.M111.309252. Epub 2011 Oct 24.

PMID:
22027841
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

ATM limits incorrect end utilization during non-homologous end joining of multiple chromosome breaks.

Bennardo N, Stark JM.

PLoS Genet. 2010 Nov 4;6(11):e1001194. doi: 10.1371/journal.pgen.1001194.

PMID:
21079684
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

I-SceI-based assays to examine distinct repair outcomes of mammalian chromosomal double strand breaks.

Gunn A, Stark JM.

Methods Mol Biol. 2012;920:379-91. doi: 10.1007/978-1-61779-998-3_27.

PMID:
22941618
[PubMed - indexed for MEDLINE]
4.

DNA-PKcs and ATM co-regulate DNA double-strand break repair.

Shrivastav M, Miller CA, De Haro LP, Durant ST, Chen BP, Chen DJ, Nickoloff JA.

DNA Repair (Amst). 2009 Aug 6;8(8):920-9. doi: 10.1016/j.dnarep.2009.05.006. Epub 2009 Jun 16.

PMID:
19535303
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks.

Yu Y, Mahaney BL, Yano K, Ye R, Fang S, Douglas P, Chen DJ, Lees-Miller SP.

DNA Repair (Amst). 2008 Oct 1;7(10):1680-92. doi: 10.1016/j.dnarep.2008.06.015. Epub 2008 Aug 3.

PMID:
18644470
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks.

Zha S, Guo C, Boboila C, Oksenych V, Cheng HL, Zhang Y, Wesemann DR, Yuen G, Patel H, Goff PH, Dubois RL, Alt FW.

Nature. 2011 Jan 13;469(7329):250-4. doi: 10.1038/nature09604. Epub 2010 Dec 15.

PMID:
21160472
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Ataxia telangiectasia mutated (ATM) is dispensable for endonuclease I-SceI-induced homologous recombination in mouse embryonic stem cells.

Rass E, Chandramouly G, Zha S, Alt FW, Xie A.

J Biol Chem. 2013 Mar 8;288(10):7086-95. doi: 10.1074/jbc.M112.445825. Epub 2013 Jan 26.

PMID:
23355489
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Rad50 zinc hook is important for the Mre11 complex to bind chromosomal DNA double-stranded breaks and initiate various DNA damage responses.

He J, Shi LZ, Truong LN, Lu CS, Razavian N, Li Y, Negrete A, Shiloach J, Berns MW, Wu X.

J Biol Chem. 2012 Sep 14;287(38):31747-56. doi: 10.1074/jbc.M112.384750. Epub 2012 Jul 25.

PMID:
22833675
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination.

Lee BS, Gapud EJ, Zhang S, Dorsett Y, Bredemeyer A, George R, Callen E, Daniel JA, Osipovich O, Oltz EM, Bassing CH, Nussenzweig A, Lees-Miller S, Hammel M, Chen BP, Sleckman BP.

Mol Cell Biol. 2013 Sep;33(18):3568-79. doi: 10.1128/MCB.00308-13. Epub 2013 Jul 8.

PMID:
23836881
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation.

Gapud EJ, Dorsett Y, Yin B, Callen E, Bredemeyer A, Mahowald GK, Omi KQ, Walker LM, Bednarski JJ, McKinnon PJ, Bassing CH, Nussenzweig A, Sleckman BP.

Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):2022-7. doi: 10.1073/pnas.1013295108. Epub 2011 Jan 18.

PMID:
21245316
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

DNA-dependent protein kinase regulates DNA end resection in concert with Mre11-Rad50-Nbs1 (MRN) and ataxia telangiectasia-mutated (ATM).

Zhou Y, Paull TT.

J Biol Chem. 2013 Dec 27;288(52):37112-25. doi: 10.1074/jbc.M113.514398. Epub 2013 Nov 12.

PMID:
24220101
[PubMed - indexed for MEDLINE]
12.

Dynamics of the PI3K-like protein kinase members ATM and DNA-PKcs at DNA double strand breaks.

Davis AJ, So S, Chen DJ.

Cell Cycle. 2010 Jul 1;9(13):2529-36.

PMID:
20543558
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Regulation of ATM in DNA double strand break repair accounts for the radiosensitivity in human cells exposed to high linear energy transfer ionizing radiation.

Xue L, Yu D, Furusawa Y, Okayasu R, Tong J, Cao J, Fan S.

Mutat Res. 2009 Nov 2;670(1-2):15-23. doi: 10.1016/j.mrfmmm.2009.06.016. Epub 2009 Jul 5.

PMID:
19583974
[PubMed - indexed for MEDLINE]
14.

Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX.

Douglas P, Zhong J, Ye R, Moorhead GB, Xu X, Lees-Miller SP.

Mol Cell Biol. 2010 Mar;30(6):1368-81. doi: 10.1128/MCB.00741-09. Epub 2010 Jan 11.

PMID:
20065038
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Repair of chromosomal RAG-mediated DNA breaks by mutant RAG proteins lacking phosphatidylinositol 3-like kinase consensus phosphorylation sites.

Gapud EJ, Lee BS, Mahowald GK, Bassing CH, Sleckman BP.

J Immunol. 2011 Aug 15;187(4):1826-34. doi: 10.4049/jimmunol.1101388. Epub 2011 Jul 8.

PMID:
21742970
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks.

Helmink BA, Bredemeyer AL, Lee BS, Huang CY, Sharma GG, Walker LM, Bednarski JJ, Lee WL, Pandita TK, Bassing CH, Sleckman BP.

J Exp Med. 2009 Mar 16;206(3):669-79. doi: 10.1084/jem.20081326. Epub 2009 Feb 16.

PMID:
19221393
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes.

Helmink BA, Tubbs AT, Dorsett Y, Bednarski JJ, Walker LM, Feng Z, Sharma GG, McKinnon PJ, Zhang J, Bassing CH, Sleckman BP.

Nature. 2011 Jan 13;469(7329):245-9. doi: 10.1038/nature09585. Epub 2010 Dec 15. Erratum in: Nature. 2011 Apr 14;472(7342):247.

PMID:
21160476
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Artemis and nonhomologous end joining-independent influence of DNA-dependent protein kinase catalytic subunit on chromosome stability.

Stracker TH, Williams BR, Deriano L, Theunissen JW, Adelman CA, Roth DB, Petrini JH.

Mol Cell Biol. 2009 Jan;29(2):503-14. doi: 10.1128/MCB.01354-08. Epub 2008 Nov 17.

PMID:
19015239
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair.

Sharma GG, So S, Gupta A, Kumar R, Cayrou C, Avvakumov N, Bhadra U, Pandita RK, Porteus MH, Chen DJ, Cote J, Pandita TK.

Mol Cell Biol. 2010 Jul;30(14):3582-95. doi: 10.1128/MCB.01476-09. Epub 2010 May 17.

PMID:
20479123
[PubMed - indexed for MEDLINE]
Free PMC Article

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