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Results: 1 to 20 of 70

1.

The major central endocannabinoid directly acts at GABA(A) receptors.

Sigel E, Baur R, Rácz I, Marazzi J, Smart TG, Zimmer A, Gertsch J.

Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):18150-5. doi: 10.1073/pnas.1113444108. Epub 2011 Oct 24.

PMID:
22025726
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The inhibitory action of exo- and endocannabinoids on [³H]GABA release are mediated by both CB₁and CB₂receptors in the mouse hippocampus.

Andó RD, Bíró J, Csölle C, Ledent C, Sperlágh B.

Neurochem Int. 2012 Jan;60(2):145-52. doi: 10.1016/j.neuint.2011.11.012. Epub 2011 Nov 22.

PMID:
22133429
[PubMed - indexed for MEDLINE]
3.

Multiple roles for the first transmembrane domain of GABAA receptor subunits in neurosteroid modulation and spontaneous channel activity.

Baker C, Sturt BL, Bamber BA.

Neurosci Lett. 2010 Apr 12;473(3):242-7. doi: 10.1016/j.neulet.2010.02.058. Epub 2010 Mar 1.

PMID:
20193738
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Partial agonism by 3alpha,21-dihydroxy-5beta-pregnan-20-one at the gamma-aminobutyric acidA receptor neurosteroid site.

Xue BG, Whittemore ER, Park CH, Woodward RM, Lan NC, Gee KW.

J Pharmacol Exp Ther. 1997 Jun;281(3):1095-101.

PMID:
9190841
[PubMed - indexed for MEDLINE]
Free Article
5.

Endocannabinoids are expressed in bone marrow stromal niches and play a role in interactions of hematopoietic stem and progenitor cells with the bone marrow microenvironment.

Jiang S, Zagozdzon R, Jorda MA, Parmar K, Fu Y, Williams JS, Wood JA, Makriyannis A, Banu N, Avraham S, Groopman JE, Avraham HK.

J Biol Chem. 2010 Nov 12;285(46):35471-8. doi: 10.1074/jbc.M110.144758. Epub 2010 Sep 7. Retraction in: J Biol Chem. 2011 Jul 8;286(27):24534.

PMID:
20826813
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Endogenous gamma-aminobutyric acid (GABA)(A) receptor active neurosteroids and the sedative/hypnotic action of gamma-hydroxybutyric acid (GHB): a study in GHB-S (sensitive) and GHB-R (resistant) rat lines.

Barbaccia ML, Carai MA, Colombo G, Lobina C, Purdy RH, Gessa GL.

Neuropharmacology. 2005 Jul;49(1):48-58. Epub 2005 Mar 31.

PMID:
15992580
[PubMed - indexed for MEDLINE]
7.

Decreased GABAA and GABAB receptor functional activity in cannabinoid CB1 receptor knockout mice.

Urigüen L, García-Gutiérrez MS, Manzanares J.

J Psychopharmacol. 2011 Jan;25(1):105-10. doi: 10.1177/0269881109358204. Epub 2010 Feb 8.

PMID:
20142297
[PubMed - indexed for MEDLINE]
8.

Structure of alpha6 beta3 delta GABA(A) receptors and their lack of ethanol sensitivity.

Baur R, Kaur KH, Sigel E.

J Neurochem. 2009 Dec;111(5):1172-81. doi: 10.1111/j.1471-4159.2009.06387.x. Epub 2009 Sep 18.

PMID:
19765192
[PubMed - indexed for MEDLINE]
9.

Neurosteroid modulation of recombinant rat alpha5beta2gamma2L and alpha1beta2gamma2L GABA(A) receptors in Xenopus oocyte.

Rahman M, Lindblad C, Johansson IM, Bäckström T, Wang MD.

Eur J Pharmacol. 2006 Oct 10;547(1-3):37-44. Epub 2006 Jul 27.

PMID:
16934248
[PubMed - indexed for MEDLINE]
10.

Abnormal mGlu 5 receptor/endocannabinoid coupling in mice lacking FMRP and BC1 RNA.

Maccarrone M, Rossi S, Bari M, De Chiara V, Rapino C, Musella A, Bernardi G, Bagni C, Centonze D.

Neuropsychopharmacology. 2010 Jun;35(7):1500-9. doi: 10.1038/npp.2010.19. Epub 2010 Mar 10.

PMID:
20393458
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Diversity of structure and function of alpha1alpha6beta3delta GABAA receptors: comparison with alpha1beta3delta and alpha6beta3delta receptors.

Baur R, Kaur KH, Sigel E.

J Biol Chem. 2010 Jun 4;285(23):17398-405. doi: 10.1074/jbc.M110.108670. Epub 2010 Apr 9.

PMID:
20382738
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Activation of type 5 metabotropic glutamate receptors and diacylglycerol lipase-α initiates 2-arachidonoylglycerol formation and endocannabinoid-mediated analgesia.

Gregg LC, Jung KM, Spradley JM, Nyilas R, Suplita RL 2nd, Zimmer A, Watanabe M, Mackie K, Katona I, Piomelli D, Hohmann AG.

J Neurosci. 2012 Jul 11;32(28):9457-68. doi: 10.1523/JNEUROSCI.0013-12.2012.

PMID:
22787031
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Pharmacological activation of kainate receptors drives endocannabinoid mobilization.

Lourenço J, Matias I, Marsicano G, Mulle C.

J Neurosci. 2011 Mar 2;31(9):3243-8. doi: 10.1523/JNEUROSCI.3512-10.2011.

PMID:
21368036
[PubMed - indexed for MEDLINE]
Free Article
14.

2-arachidonyl glycerol activates platelets via conversion to arachidonic acid and not by direct activation of cannabinoid receptors.

Keown OP, Winterburn TJ, Wainwright CL, Macrury SM, Neilson I, Barrett F, Leslie SJ, Megson IL.

Br J Clin Pharmacol. 2010 Aug;70(2):180-8. doi: 10.1111/j.1365-2125.2010.03697.x.

PMID:
20653671
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Molecular analysis of the site for 2-arachidonylglycerol (2-AG) on the β₂ subunit of GABA(A) receptors.

Baur R, Kielar M, Richter L, Ernst M, Ecker GF, Sigel E.

J Neurochem. 2013 Jul;126(1):29-36. doi: 10.1111/jnc.12270. Epub 2013 May 3.

PMID:
23600744
[PubMed - indexed for MEDLINE]
16.

The effect of a transmembrane amino acid on etomidate sensitivity of an invertebrate GABA receptor.

McGurk KA, Pistis M, Belelli D, Hope AG, Lambert JJ.

Br J Pharmacol. 1998 May;124(1):13-20.

PMID:
9630337
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Neurosteroidogenesis: relevance to neurosteroid actions in brain and modulation by psychotropic drugs.

Barbaccia ML.

Crit Rev Neurobiol. 2004;16(1-2):67-74. Review.

PMID:
15581401
[PubMed - indexed for MEDLINE]
18.

Differential effects of two major neurosteroids on cerebellar and cortical GABA(A) receptor binding and function.

Maksay G, Fodor L.

Eur J Pharmacol. 2011 Jan 10;650(1):94-101. doi: 10.1016/j.ejphar.2010.10.003. Epub 2010 Oct 14.

PMID:
20951124
[PubMed - indexed for MEDLINE]
19.

3Alpha-hydroxy-5alpha-pregnan-20-one levels and GABA(A) receptor-mediated 36Cl(-) flux across development in rat cerebral cortex.

Grobin AC, Morrow AL.

Brain Res Dev Brain Res. 2001 Nov 26;131(1-2):31-9.

PMID:
11718833
[PubMed - indexed for MEDLINE]
20.

The antinociceptive triterpene β-amyrin inhibits 2-arachidonoylglycerol (2-AG) hydrolysis without directly targeting cannabinoid receptors.

Chicca A, Marazzi J, Gertsch J.

Br J Pharmacol. 2012 Dec;167(8):1596-608. doi: 10.1111/j.1476-5381.2012.02059.x.

PMID:
22646533
[PubMed - indexed for MEDLINE]
Free PMC Article

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