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Items: 1 to 20 of 105


Hck tyrosine kinase regulates TLR4-induced TNF and IL-6 production via AP-1.

Smolinska MJ, Page TH, Urbaniak AM, Mutch BE, Horwood NJ.

J Immunol. 2011 Dec 1;187(11):6043-51. doi: 10.4049/jimmunol.1100967. Epub 2011 Oct 21.


Bruton's tyrosine kinase is required for TLR2 and TLR4-induced TNF, but not IL-6, production.

Horwood NJ, Page TH, McDaid JP, Palmer CD, Campbell J, Mahon T, Brennan FM, Webster D, Foxwell BM.

J Immunol. 2006 Mar 15;176(6):3635-41.


AP-1 activated by toll-like receptors regulates expression of IL-23 p19.

Liu W, Ouyang X, Yang J, Liu J, Li Q, Gu Y, Fukata M, Lin T, He JC, Abreu M, Unkeless JC, Mayer L, Xiong H.

J Biol Chem. 2009 Sep 4;284(36):24006-16. doi: 10.1074/jbc.M109.025528. Epub 2009 Jul 10.


TGF-β1 re-programs TLR4 signaling in L. donovani infection: enhancement of SHP-1 and ubiquitin-editing enzyme A20.

Das S, Pandey K, Kumar A, Sardar AH, Purkait B, Kumar M, Kumar S, Ravidas VN, Roy S, Singh D, Das P.

Immunol Cell Biol. 2012 Jul;90(6):640-54. doi: 10.1038/icb.2011.80. Epub 2011 Oct 4.


TLR ligand decreases mesenteric ischemia and reperfusion injury-induced gut damage through TNF-alpha signaling.

Chen LW, Chang WJ, Chen PH, Liu WC, Hsu CM.

Shock. 2008 Nov;30(5):563-70. doi: 10.1097/SHK.0b013e31816a3458.


Scaffolding adaptor protein Gab1 is required for TLR3/4- and RIG-I-mediated production of proinflammatory cytokines and type I IFN in macrophages.

Zheng Y, An H, Yao M, Hou J, Yu Y, Feng G, Cao X.

J Immunol. 2010 Jun 1;184(11):6447-56. doi: 10.4049/jimmunol.0901750. Epub 2010 Apr 30.


Bmx tyrosine kinase regulates TLR4-induced IL-6 production in human macrophages independently of p38 MAPK and NFkapp}B activity.

Palmer CD, Mutch BE, Workman S, McDaid JP, Horwood NJ, Foxwell BM.

Blood. 2008 Feb 15;111(4):1781-8. Epub 2007 Nov 19.


Signaling pathways for tumor necrosis factor-alpha and interleukin-6 expression in human macrophages exposed to titanium-alloy particulate debris in vitro.

Nakashima Y, Sun DH, Trindade MC, Maloney WJ, Goodman SB, Schurman DJ, Smith RL.

J Bone Joint Surg Am. 1999 May;81(5):603-15.


Sensitivity of TLR4- and -7-induced NF kappa B1 p105-TPL2-ERK pathway to TNF-receptor-associated-factor-6 revealed by RNAi in mouse macrophages.

Loniewski KJ, Patial S, Parameswaran N.

Mol Immunol. 2007 Jul;44(15):3715-23. Epub 2007 May 15.


Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3.

Huang Q, Yang J, Lin Y, Walker C, Cheng J, Liu ZG, Su B.

Nat Immunol. 2004 Jan;5(1):98-103. Epub 2003 Dec 7.


IL-17 stimulates MMP-1 expression in primary human cardiac fibroblasts via p38 MAPK- and ERK1/2-dependent C/EBP-beta , NF-kappaB, and AP-1 activation.

Cortez DM, Feldman MD, Mummidi S, Valente AJ, Steffensen B, Vincenti M, Barnes JL, Chandrasekar B.

Am J Physiol Heart Circ Physiol. 2007 Dec;293(6):H3356-65. Epub 2007 Oct 5.


Expression of TRAF6 and pro-inflammatory cytokines through activation of TLR2, TLR4, NOD1, and NOD2 in human periodontal ligament fibroblasts.

Tang L, Zhou XD, Wang Q, Zhang L, Wang Y, Li XY, Huang DM.

Arch Oral Biol. 2011 Oct;56(10):1064-72. doi: 10.1016/j.archoralbio.2011.02.020. Epub 2011 Mar 31.


The Src family kinase Hck regulates mast cell activation by suppressing an inhibitory Src family kinase Lyn.

Hong H, Kitaura J, Xiao W, Horejsi V, Ra C, Lowell CA, Kawakami Y, Kawakami T.

Blood. 2007 Oct 1;110(7):2511-9. Epub 2007 May 18. Erratum in: Blood. 2008 Mar 15;111(6):3299.

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